Job Description O01798 Confidence 100.00% Date Fri May 3 21:22:31 BST 2013 Rank 211 Aligned Residues 251 % Identity 21% Template c3mtfB_ PDB info PDB header:transferase Chain: B: PDB Molecule:activin receptor type-1; PDBTitle: crystal structure of the acvr1 kinase in complex with a 2-2 aminopyridine inhibitor Resolution 2.15 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		215	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.					.	.	.	290
Predicted Secondary structure																																																																										.	.	.	.
Query SS confidence																																																																										.	.	.	.
Query Sequence		E	Q	V	T	L	N	K	K	L	G	E	G	Q	F	G	E	V	H	K	G	S	L	K	T	S	V	F	A	A	P	V	T	V	A	V	K	T	L	H	Q	N	H	L	S	A	N	E	K	I	L	F	L	R	E	A	N	V	M	L	T	L	S	H	P	N	V	I	K	F	Y	G	V	.	.	.	.	C	T	M	K
Query Conservation																																																																										.	.	.	.
Alig confidence																											.	.	.	.	.	.																	.	.	.																							.	.	.	.
Template Conservation																											.	.	.	.	.	.																	.	.	.
Template Sequence		R	D	I	T	L	L	E	C	V	G	K	G	R	Y	G	E	V	W	R	G	S	W	Q	G	E	.	.	.	.	.	.	N	V	A	V	K	I	F	S	S	R	D	E	K	S	W	F	.	.	.	R	E	T	E	L	Y	N	T	V	M	L	R	H	E	N	I	L	G	F	I	A	S	D	M	T	S	R	H	S	S
Template Known Secondary structure		T	T											T	T									T	T		.	.	.	.	.	.									G	G	G						.	.	.									S					T	T	B												T	T
Template Predicted Secondary structure																											.	.	.	.	.	.																	.	.	.
Template SS confidence
		206	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230							.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.				.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.
		291	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340									.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.
Predicted Secondary structure																																																				.	.	.	.	.	.	.	.
Query SS confidence																																																				.	.	.	.	.	.	.	.
Query Sequence		E	P	I	M	I	V	M	E	F	C	D	G	K	S	L	E	D	A	L	L	S	K	E	E	K	V	S	A	E	D	K	I	L	Y	L	F	H	A	A	C	G	I	D	Y	L	H	G	K	Q	V	.	.	.	.	.	.	.	.	I	H	R	D	I	A	A	R	N	C	L	L	N	S	K	K	I	L	K	I	S	D
Query Conservation																																																				.	.	.	.	.	.	.	.
Alig confidence																					.	.																														.	.	.	.	.	.	.	.
Template Conservation																					.	.
Template Sequence		T	Q	L	W	L	I	T	H	Y	H	E	M	G	S	L	Y	D	Y	L	.	.	Q	L	T	T	L	D	T	V	S	C	L	R	I	V	L	S	I	A	S	G	L	A	H	L	H	I	E	I	F	G	T	Q	G	K	P	A	I	A	H	R	D	L	K	S	K	N	I	L	V	K	K	N	G	Q	C	C	I	A	D
Template Known Secondary structure												T	T		B						.	.					B																					S		B		S	T	T		B						S			S	G	G	G					T	T	S
Template Predicted Secondary structure																					.	.
Template SS confidence
		277	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.			.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.
		363	.	.	.	.	.						.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.							.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.
Predicted Secondary structure								.	.	.	.	.																											.	.	.	.	.	.																												.	.	.	.	.	.	.	.	.	.
Query SS confidence								.	.	.	.	.																											.	.	.	.	.	.																												.	.	.	.	.	.	.	.	.	.
Query Sequence		F	G	L	S	V	K	.	.	.	.	.	G	V	A	I	K	E	R	K	G	G	C	L	P	V	K	Y	M	A	P	E	T	L	K	K	G	L	.	.	.	.	.	.	Y	S	T	A	S	D	I	Y	S	Y	G	A	L	M	Y	E	V	Y	T	D	G	K	T	P	F	E	T	.	.	.	.	.	.	.	.	.	.
Query Conservation								.	.	.	.	.																											.	.	.	.	.	.																												.	.	.	.	.	.	.	.	.	.
Alig confidence								.	.	.	.	.																											.	.	.	.	.	.																				.								.	.	.	.	.	.	.	.	.	.
Template Conservation																																																																.
Template Sequence		L	G	L	A	V	M	H	S	Q	S	T	N	Q	L	D	V	G	N	N	P	R	V	G	T	K	R	Y	M	A	P	E	V	L	D	E	T	I	Q	V	D	C	F	D	S	Y	K	R	V	D	I	W	A	F	G	L	V	L	W	E	V	A	R	.	R	M	V	S	N	G	I	V	E	D	Y	K	P	P	F	Y	D
Template Known Secondary structure			T	T						T	T	T	T													G	G	G							T	T				T	T																						T	.	T	B		B	T	T	B							T	T	T	T
Template Predicted Secondary structure																																																																.
Template SS confidence
		355	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.		.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.
					422	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.						.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.
Predicted Secondary structure		.	.	.																									.	.	.	.	.
Query SS confidence		.	.	.																									.	.	.	.	.
Query Sequence		.	.	.	C	G	L	R	G	N	E	L	R	K	A	I	I	G	K	R	I	S	L	A	V	E	V	E	.	.	.	.	.	L	P	V	F	I	A	N	I	F	E	Q	S	R	Q	Y	E	T	E	D	R	I	S	S	K	Q	I	I	Q	I	F	K	E
Query Conservation		.	.	.																									.	.	.	.	.
Alig confidence		.	.	.																									.	.	.	.	.
Template Conservation
Template Sequence		V	V	P	N	D	P	S	F	E	D	M	R	K	V	V	C	V	D	Q	Q	R	P	N	I	P	N	R	W	F	S	D	P	T	L	T	S	L	A	K	L	M	K	E	C	W	Y	Q	N	P	S	A	R	L	T	A	L	R	I	K	K	T	L	T	K
Template Known Secondary structure		T	S		S	S											T	T	S								G	G	G	G	G	S																S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		434	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D