Job Description O01798 Confidence 100.00% Date Fri May 3 21:22:31 BST 2013 Rank 205 Aligned Residues 247 % Identity 23% Template c3kvwA_ PDB info PDB header:transferase Chain: A: PDB Molecule:dual specificity tyrosine-phosphorylation-regulated kinase PDBTitle: crystal structure of dual-specificity tyrosine phosphorylation2 regulated kinase 2 (dyrk2) in complex with an indirubin ligand Resolution 2.28 Å

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		214	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.							.	.	280	.	.	.	.	.	.	.
Predicted Secondary structure																																																																		.	.	.	.	.	.
Query SS confidence																																																																		.	.	.	.	.	.
Query Sequence		N	E	Q	V	T	L	N	K	K	L	G	E	G	Q	F	G	E	V	H	K	G	S	L	K	T	S	V	F	A	A	P	V	T	V	A	V	K	T	L	H	Q	N	H	L	S	A	N	E	K	I	L	F	L	R	E	A	N	V	M	L	T	L	S	H	.	.	.	.	.	.	P	N	V	I	K	F	Y	G	V	C
Query Conservation																																																																		.	.	.	.	.	.
Alig confidence																												.	.	.	.																			.	.	.														.	.	.	.	.	.
Template Conservation																												.	.	.	.																			.	.	.
Template Sequence		A	Y	R	Y	E	V	L	K	V	I	G	K	G	S	F	G	Q	V	V	K	A	Y	D	H	K	V	.	.	.	.	H	Q	H	V	A	L	K	M	V	R	N	E	K	R	F	H	R	Q	.	.	.	A	A	E	E	I	R	I	L	E	H	L	R	K	Q	D	K	D	N	T	M	N	V	I	H	M	L	E	N	F
Template Known Secondary structure		T	T	T										S	S	S									T	T	T	.	.	.	.	T										S								.	.	.													T	T		T	T	S		S		B
Template Predicted Secondary structure																												.	.	.	.																			.	.	.
Template SS confidence
		146	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.					.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.				190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.
		288	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.			.	.	.	360	.	.	.	.	.
Predicted Secondary structure																																																																							.	.
Query SS confidence																																																																							.	.
Query Sequence		T	M	K	E	P	I	M	I	V	M	E	F	C	D	G	K	S	L	E	D	A	L	L	S	K	E	E	K	V	S	A	E	D	K	I	L	Y	L	F	H	A	A	C	G	I	D	Y	L	H	G	K	Q	V	I	H	R	D	I	A	A	R	N	C	L	L	N	S	K	K	.	.	I	L	K	I	S	D	F	G	L
Query Conservation																																																																							.	.
Alig confidence																																																																							.	.
Template Conservation
Template Sequence		T	F	R	N	H	I	C	M	T	F	E	L	L	S	M	N	L	Y	E	L	I	K	K	N	K	F	Q	G	F	S	L	P	L	V	R	K	F	A	H	S	I	L	Q	C	L	D	A	L	H	K	N	R	I	I	H	C	D	L	K	P	E	N	I	L	L	K	Q	Q	G	R	S	G	I	K	V	I	D	F	G	S
Template Known Secondary structure				T	T												B								T	T	T																										T				S			S	G	G	G				S	S	T	T	S									T	T
Template Predicted Secondary structure
Template SS confidence
		219	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.
		366	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.
Predicted Secondary structure																																																																														.	.	.	.
Query SS confidence																																																																														.	.	.	.
Query Sequence		S	V	K	G	V	A	I	K	E	R	K	G	G	C	L	P	V	K	Y	M	A	P	E	T	L	K	K	G	L	Y	S	T	A	S	D	I	Y	S	Y	G	A	L	M	Y	E	V	Y	T	D	G	K	T	P	F	E	T	C	G	L	R	G	N	E	L	R	K	A	I	I	G	K	R	I	S	L	A	.	.	.	.
Query Conservation																																																																														.	.	.	.
Alig confidence				.	.	.																																												.						.	.																					.	.	.	.
Template Conservation				.	.	.																																												.						.	.
Template Sequence		S	C	.	.	.	Y	E	H	Q	R	V	Y	T	I	Q	S	R	F	Y	R	A	P	E	V	I	L	G	A	R	Y	G	M	P	I	D	M	W	S	L	G	C	I	L	A	E	L	L	T	.	G	Y	P	L	L	.	.	P	G	E	D	E	G	D	Q	L	A	C	M	I	E	L	L	G	M	P	S	Q	K	L	L
Template Known Secondary structure				.	.	.		T	T									G	G	G								T	B				T																	.	S	S		S	S	.	.			S	S
Template Predicted Secondary structure				.	.	.																																												.						.	.
Template SS confidence
		299	300				.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.		.	.	.	.	.			.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.
																																																				442	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	V	E	V	E	L	P	V	F	I	A	N	I	F	E	Q	S	R	Q	Y	E	T	E	D	R	I	S	S	K	Q	I
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		D	A	S	K	R	A	K	N	F	V	S	K	G	Y	P	R	Y	C	T	V	T	T	L	S	D	V	V	L	N	G	G	R	S	R	R	G	K	L	R	G	P	P	E	S	R	E	W	G	N	A	L	K	G	C	D	D	P	L	F	L	D	F	L	K	Q	C	L	E	W	D	P	A	V	R	M	T	P	G	Q	A
Template Known Secondary structure			T	B	T	T					B					B	T	T	S																T	T						S	T	T		S						T	T	T														T		S	S	T	T	T	S
Template Predicted Secondary structure
Template SS confidence
		374	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.
		472	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	Q
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	R
Template Known Secondary structure			T
Template Predicted Secondary structure
Template SS confidence
		457	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D