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Job DescriptionO01798
Confidence100.00%DateFri May 3 21:22:31 BST 2013
Rank176Aligned Residues237
% Identity32%Templatec3k54A_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase btk; PDBTitle: structures of human bruton's tyrosine kinase in active and inactive2 conformations suggests a mechanism of activation for tec family3 kinases.
Resolution1.94 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   208.210.........220.........230.........240.........250.........260.........270.........280.......
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Query Sequence  HGWQLNNEQVTLNKKLGEGQFGEVHKGSLKTSVFAAPVTVAVKTLHQNHLSANEKILFLREANVMLTLSHPNVIKFYGVC
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Template Sequence  GSWEIDPKDLTFLKELGTGQFGVVKYGKWRGQ. . . . . YDVAIKMIKE. . . . . . . . . . FIEEAKVMMNLSHEKLVQLYGVC
Template Known Secondary structure  GGGB

GGGSTTSS
TTT.....


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TT


TTB

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   393......400.........410.........420.... .....430.... .....440.........450.......
 
   288.290.........300.........310.........320.........330.........340.........350.........360.......
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Query Sequence  TMKEPIMIVMEFCDGKSLEDALLSKEEKVSAEDKILYLFHAACGIDYLHGKQVIHRDIAARNCLLNSKKILKISDFGLSV
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Template Sequence  TKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGFP.
Template Known Secondary structure 
SSSS


TT
GGG


TT


S

SGGG
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   465....470.........480.........490.........500.........510.........520.........530.........540...
 
   368.370.........380.........390.........400.........410.........420.........430.........440.......
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Query Sequence  KGVAIKERKGGCLPVKYMAPETLKKGLYSTASDIYSYGALMYEVYTDGKTPFETCGLRGNELRKAIIGKRISLAVEVELP
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Template Sequence  . . . . . . . . . . . . . . VRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPY. . ERFTNSETAEHIAQG. LRLYRPHLAS
Template Known Secondary structure  ..............GGG





TTS

TT..TTS
TT.





TTS
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   561........570.........580.........590........ .600.........610... ......620...
 
   448.450.........460.........470.......
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Query Sequence  VFIANIFEQSRQYETEDRISSKQIIQIFKE
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Template Sequence  EKVYTIMYSCWHEKADERPTFKILLSNILD
Template Known Secondary structure  TT
SSGGGS

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   624.....630.........640.........650...
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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