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Job DescriptionO01798
Confidence100.00%DateFri May 3 21:22:31 BST 2013
Rank265Aligned Residues249
% Identity28%Templatec3c1xA_
PDB info PDB header:transferaseChain: A: PDB Molecule:hepatocyte growth factor receptor; PDBTitle: crystal structure of the tyrosine kinase domain of the2 hepatocyte growth factor receptor c-met in complex with a3 pyrrolotriazine based inhibitor
Resolution2.17 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   208.210...... ...220.........230.........240.........250.........260.........270.........280.....
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Query Sequence  HGWQLNNEQ. . VTLNKKLGEGQFGEVHKGSLKTSVFAAPVTVAVKTLHQNHLSANEKILFLREANVMLTLSHPNVIKFYG
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Template Sequence  QHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDND. GKKIHCAVKSLNRIT. DIGEVSQFLTEGIIMKDFSHPNVLSLLG
Template Known Secondary structure  TTTB

STT

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   1067..1070.........1080.........1090.........1100. ........1110...... ...1120.........1130.........1140....
 
   286...290. ........300.........310.........320.........330.........340.........350.........360....
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Query Sequence  VCTMKE. PIMIVMEFCDGKSLEDALLSKEEKVSAEDKILYLFHAACGIDYLHGKQVIHRDIAARNCLLNSKKILKISDFG
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Template Sequence  ICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKFLASKKFVHRDLAARNCMLDEKFTVKVADFL
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   1145....1150.........1160.........1170.........1180.........1190.........1200.........1210.........1220....
 
   365....370.........380.........390.........400.........410.........420.........430.........440....
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Query Sequence  LSVKGVAIKERKGGCLPVKYMAPETLKKGLYSTASDIYSYGALMYEVYTDGKTPFETCGLRGNELRKAIIGKRISLAVEV
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Template Sequence  PVK. . . . . . . . . . . . . . . . WMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPY. . PDVNTFDITVYLLQG. RRLLQPE
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   1246.. .1250.........1260.........1270.........1280.... .....1290......... 1300......
 
   445....450.........460.........470.......
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Query Sequence  ELPVFIANIFEQSRQYETEDRISSKQIIQIFKE
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Template Sequence  YCPDPLYEVMLKCWHPKAEMRPSFSELVSRISA
Template Known Secondary structure  T

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SSGGGS

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   1307..1310.........1320.........1330.........
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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