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Job DescriptionO01798
Confidence100.00%DateFri May 3 21:22:31 BST 2013
Rank107Aligned Residues260
% Identity22%Templatec2r7bA_
PDB info PDB header:signaling protein, transferaseChain: A: PDB Molecule:phosphoinositide-dependent protein kinase 1; PDBTitle: crystal structure of the phosphoinositide-dependent kinase-2 1 (pdk-1)catalytic domain bound to a dibenzonaphthyridine3 inhibitor
Resolution2.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
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Query Sequence  EQVTLNKKLGEGQFGEVHKGSLKTSVFAAPVTVAVKTLHQNHLSANE. KILFLREANVMLTLSHPNVIKFYGVCTMKEPI
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Template Sequence  EDFKFGKILGEGSFSTVVLARELAT. . . . SREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKL
Template Known Secondary structure  GG
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TTT....

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   80.........90.........100.... .....110.........120.........130.........140.........150.....
 
   294.....300.........310.........320.........330.........340.........350.........360.........370...
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Query Sequence  MIVMEFCDGKSLEDALLSKEEKVSAEDKILYLFHAACGIDYLHGKQVIHRDIAARNCLLNSKKILKISDFGLSVKGVAIK
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Template Sequence  YFGLSYAKNGELLKYIRKIGS. FDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVL. . . .
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   156...160.........170...... ...180.........190.........200.........210.........220.........230
 
   374.....380.........390.........400.........410.........420.........430.........440.........450...
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Query Sequence  ERKGGCLPVKYMAPETLKKGLYSTASDIYSYGALMYEVYTDGKTPFETCGLRGNELRKAIIGKRISLAVEVELPVFIANI
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Template Sequence  . . . . FVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVA. GLPPF. . RAGNEYLIFQKIIKLE. . YDFPEKFFPKARDL
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GGG

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   242.......250.........260.........270....... ..280.. .......290........ .300.........310..
 
   454.....460.........470.... .....480.........490..
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Query Sequence  FEQSRQYETEDRISSKQIIQI. . FKEEVGFHEIETSGILHK
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Template Sequence  VEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQ
Template Known Secondary structure  TTS
SSTTSSTTSGGGTTSGGGTT

GGGGGGS
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   313......320.........330.........340.........350...
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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