Job Description O01798 Confidence 100.00% Date Fri May 3 21:22:31 BST 2013 Rank 275 Aligned Residues 245 % Identity 19% Template c2pvmA_ PDB info PDB header:transferase Chain: A: PDB Molecule:casein kinase ii subunit alpha; PDBTitle: structure-based design of pyrazolo[1,5-a][1,3,5]triazine2 derivatives as potent inhibitors of protein kinase ck2 Resolution 2.00 Å

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		215	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.			.
Predicted Secondary structure																																																																															.	.
Query SS confidence																																																																															.	.
Query Sequence		E	Q	V	T	L	N	K	K	L	G	E	G	Q	F	G	E	V	H	K	G	S	L	K	T	S	V	F	A	A	P	V	T	V	A	V	K	T	L	H	Q	N	H	L	S	A	N	E	K	I	L	F	L	R	E	A	N	V	M	L	T	L	S	H	P	N	V	I	K	F	Y	G	V	C	T	M	K	E	.	.	P
Query Conservation																																																																															.	.
Alig confidence																											.	.	.	.														.	.	.	.	.																															.	.
Template Conservation																											.	.	.	.														.	.	.	.	.
Template Sequence		D	D	Y	E	V	V	R	K	V	G	R	G	K	Y	S	E	V	F	E	G	I	N	V	N	N	.	.	.	.	N	E	K	C	I	I	K	I	L	K	P	V	K	.	.	.	.	.	K	K	K	I	K	R	E	I	K	I	L	Q	N	L	G	G	P	N	I	V	K	L	L	D	I	V	R	D	Q	H	S	K	T
Template Known Secondary structure		G	G											S	S									T	T	T	.	.	.	.											S			.	.	.	.	.																	T	T	B										T	T	T
Template Predicted Secondary structure																											.	.	.	.														.	.	.	.	.
Template SS confidence
		37	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.					.	.	.	.	.	.	.	.	70	.	.	.	.						.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.
		293	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.		.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.
Predicted Secondary structure																																																															.
Query SS confidence																																																															.
Query Sequence		I	M	I	V	M	E	F	C	D	G	K	S	L	E	D	A	L	L	S	K	E	E	K	V	S	A	E	D	K	I	L	Y	L	F	H	A	A	C	G	I	D	Y	L	H	G	K	Q	V	I	H	R	D	I	A	A	R	N	C	L	L	N	.	S	K	K	I	L	K	I	S	D	F	G	L	S	V	K	G	V	A
Query Conservation																																																															.
Alig confidence																					.	.	.	.																																							.
Template Conservation																					.	.	.	.
Template Sequence		P	S	L	I	F	E	Y	V	N	N	T	D	F	K	V	L	Y	P	T	.	.	.	.	L	T	D	Y	D	I	R	Y	Y	I	Y	E	L	L	K	A	L	D	Y	C	H	S	Q	G	I	M	H	R	D	V	K	P	H	N	V	M	I	D	H	E	L	R	K	L	R	L	I	D	W	G	L	A	E	F	Y	H	P
Template Known Secondary structure																		G	G	G	.	.	.	.																							T	T							S	G	G	G					T	T	T	T								T	T						T
Template Predicted Secondary structure																					.	.	.	.
Template SS confidence
		109	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.					.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.
		372	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.		.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.
Predicted Secondary structure																							.																																											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																							.																																											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		I	K	E	R	K	G	G	C	L	P	V	K	Y	M	A	P	E	T	L	K	K	.	G	L	Y	S	T	A	S	D	I	Y	S	Y	G	A	L	M	Y	E	V	Y	T	D	G	K	T	P	F	E	T	C	G	L	R	G	N	E	L	R	K	A	I	I	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Conservation																							.																																											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																							.																						.																					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																													.
Template Sequence		G	K	E	Y	N	V	R	V	A	S	R	Y	F	K	G	P	E	L	L	V	D	L	Q	D	Y	D	Y	S	L	D	M	W	S	L	G	C	M	F	A	G	M	I	F	.	R	K	E	P	F	F	Y	G	H	D	N	H	D	Q	L	V	K	I	A	K	V	L	G	T	D	G	L	N	A	Y	L	N	K	Y	R	I
Template Known Secondary structure		T					S			S		G	G	G							T	T			S			T																	.	T		S	S	S	S			S	S																								T	T
Template Predicted Secondary structure																																													.
Template SS confidence
		185	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.		.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.
																				435	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	G	K	R	I	S	L	A	V	E	V	E	L	P	V	F	I	A	N	I	F	E	Q	S	R	Q	Y	E	T	E	D	R	I	S	S	K	Q	I	I	Q
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		E	L	D	P	Q	L	E	A	L	V	G	R	H	S	R	K	P	W	L	K	F	M	N	A	D	N	Q	H	L	V	S	P	E	A	I	D	F	L	D	K	L	L	R	Y	D	H	Q	E	R	L	T	A	L	E	A	M	T
Template Known Secondary structure																			G	G	G	G			T	T	T	G	G	G											T	T			S	S	T	T	T	S
Template Predicted Secondary structure
Template SS confidence
		264	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D