Job Description O01798 Confidence 100.00% Date Fri May 3 21:22:31 BST 2013 Rank 4 Aligned Residues 367 % Identity 30% Template c2h8hA_ PDB info PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: src kinase in complex with a quinazoline inhibitor Resolution 2.20 Å Model Dimensions (Å) X:63.324 Y:71.296 Z:59.069

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		97	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130					.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.						.	.	.	160	.	.	.	.	.	.	.
Predicted Secondary structure																																				.	.	.	.																											.	.	.	.	.
Query SS confidence																																				.	.	.	.																											.	.	.	.	.
Query Sequence		V	P	S	D	E	V	G	R	V	E	N	N	I	D	N	F	P	F	Y	H	G	F	M	G	R	N	E	C	E	A	M	L	S	N	.	.	.	.	H	G	D	F	L	I	R	M	T	E	I	G	K	R	V	A	Y	V	I	S	I	K	W	K	Y	Q	.	.	.	.	.	N	I	H	V	L	V	K	R	T	K	T
Query Conservation																																				.	.	.	.																											.	.	.	.	.
Alig confidence										.																										.	.	.	.											.																.	.	.	.	.
Template Conservation										.																																								.
Template Sequence		I	P	S	N	Y	V	A	P	.	S	D	S	I	Q	A	E	E	W	Y	F	G	K	I	T	R	R	E	S	E	R	L	L	L	N	A	E	N	P	R	G	T	F	L	V	R	E	S	E	.	T	T	K	G	A	Y	C	L	S	V	S	D	F	D	N	A	K	G	L	N	V	K	H	Y	K	I	R	K	L	D	S
Template Known Secondary structure				G	G	G				.	T	T	S	G	G	G	S	T	T	B			S											T		T	T			T	T								S	.	S	S	T	T											T	T	T										B		.
Template Predicted Secondary structure										.																																								.
Template SS confidence
		132	.	.	.	.	.	.	.		140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.		.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.
		168	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.									.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																																							.	.	.	.	.	.	.	.
Query SS confidence																																							.	.	.	.	.	.	.	.
Query Sequence		K	K	L	Y	W	T	K	K	Y	A	F	K	S	I	C	E	L	I	A	Y	H	K	R	N	H	K	P	I	Y	E	G	M	T	L	I	C	G	.	.	.	.	.	.	.	.	L	A	R	H	G	W	Q	L	N	N	E	Q	V	T	L	N	K	K	L	G	E	G	Q	F	G	E	V	H	K	G	S	L	K	T	S
Query Conservation																																							.	.	.	.	.	.	.	.
Alig confidence																																							.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		G	G	F	Y	I	T	S	R	T	Q	F	N	S	L	Q	Q	L	V	A	Y	Y	S	K	H	A	D	G	L	C	H	R	L	T	T	V	C	P	T	S	K	P	Q	T	Q	G	L	A	K	D	A	W	E	I	P	R	E	S	L	R	L	E	V	K	L	G	Q	G	C	F	G	E	V	W	M	G	T	W	N	G	T
Template Known Secondary structure		S						T	T				S	S													T	T	S	S	S														S	S	S	S	T	T		S	B			G	G	G											S	S									T	T	T
Template Predicted Secondary structure
Template SS confidence
		210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.
		240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.		310	.	.	.	.	.	.	.	.
Predicted Secondary structure																																																																								.
Query SS confidence																																																																								.
Query Sequence		V	F	A	A	P	V	T	V	A	V	K	T	L	H	Q	N	H	L	S	A	N	E	K	I	L	F	L	R	E	A	N	V	M	L	T	L	S	H	P	N	V	I	K	F	Y	G	V	C	T	M	K	E	P	I	M	I	V	M	E	F	C	D	G	K	S	L	E	D	A	L	.	L	S	K	E	E	K	V	S	A
Query Conservation																																																																								.
Alig confidence		.	.	.	.	.																		.	.	.																									.																					.
Template Conservation		.	.	.	.	.																		.	.	.																									.
Template Sequence		.	.	.	.	.	T	R	V	A	I	K	T	L	K	P	G	T	M	S	P	E	A	.	.	.	F	L	Q	E	A	Q	V	M	K	K	L	R	H	E	K	L	V	Q	L	Y	A	V	V	S	.	E	E	P	I	Y	I	V	T	E	Y	M	S	K	G	S	L	L	D	F	L	K	G	E	T	G	K	Y	L	R	L
Template Known Secondary structure		.	.	.	.	.										T	T	S	S					.	.	.														T	T	B									.	S	S	S									T	T								S					T	T
Template Predicted Secondary structure		.	.	.	.	.																		.	.	.																									.
Template SS confidence
							290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.				.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330		.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
		319	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.			.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.
Predicted Secondary structure																																																			.	.
Query SS confidence																																																			.	.
Query Sequence		E	D	K	I	L	Y	L	F	H	A	A	C	G	I	D	Y	L	H	G	K	Q	V	I	H	R	D	I	A	A	R	N	C	L	L	N	S	K	K	I	L	K	I	S	D	F	G	L	S	V	.	.	K	G	V	A	I	K	E	R	K	G	G	C	L	P	V	K	Y	M	A	P	E	T	L	K	K	G	L	Y	S
Query Conservation																																																			.	.
Alig confidence																																																			.	.
Template Conservation
Template Sequence		P	Q	L	V	D	M	A	A	Q	I	A	S	G	M	A	Y	V	E	R	M	N	Y	V	H	R	D	L	R	A	A	N	I	L	V	G	E	N	L	V	C	K	V	A	D	F	G	L	A	R	L	I	E	D	N	E	Y	T	A	R	Q	G	A	K	F	P	I	K	W	T	A	P	E	A	A	L	Y	G	R	F	T
Template Known Secondary structure																					T	T				S			S	G	G	G					G	G	G							T	T	S	T	T	T								T	T		S	T	T	S		G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		361	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440
		397	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		T	A	S	D	I	Y	S	Y	G	A	L	M	Y	E	V	Y	T	D	G	K	T	P	F	E	T	C	G	L	R	G	N	E	L	R	K	A	I	I	G	K	R	I	S	L	A	V	E	V	E	L	P	V	F	I	A	N	I	F	E	Q	S	R	Q	Y	E	T	E	D	R	I	S	S	K	Q	I	I	Q	I	F	K
Query Conservation
Alig confidence																									.	.																.
Template Conservation																									.	.																.
Template Sequence		I	K	S	D	V	W	S	F	G	I	L	L	T	E	L	T	T	K	G	R	V	P	Y	.	.	P	G	M	V	N	R	E	V	L	D	Q	V	E	R	G	.	Y	R	M	P	C	P	P	E	C	P	E	S	L	H	D	L	M	C	Q	C	W	R	K	E	P	E	E	R	P	T	F	E	Y	L	Q	A	F	L	E
Template Known Secondary structure																	T	T	T	T			S	S	.	.	T	T												T	T	.							T	T													T		S	S	G	G	G	S
Template Predicted Secondary structure																									.	.																.
Template SS confidence
		441	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.			.	.	.	.	.	.	470	.	.	.	.	.	.	.	.		.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.
		477
Predicted Secondary structure
Query SS confidence
Query Sequence		E
Query Conservation
Alig confidence
Template Conservation
Template Sequence		D
Template Known Secondary structure		T
Template Predicted Secondary structure
Template SS confidence
		518

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D