|   |   |
212 | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | |
. | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | |
. | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
L | N | N | E | Q | V | T | L | N | K | K | L | G | E | G | Q | F | G | E | V | H | K | G | S | L | K | T | S | V | F | A | A | P | V | T | V | A | V | K | T | L | H | Q | N | H | L | . |
S | A | N | E | K | I | L | F | L | R | E | A | N | V | M | L | T | . |
L | S | H | P | N | V | I | K | F | Y | G | V | C | T | M |
| Query Conservation |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   | . |
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|   |
|   |   |
|   |   |   |   |   |
|
|   |
|   |
|
|   |
|
|   |
|   |   |   |   |
| . | . | . | . |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
L | G | L | Q | D | F | D | L | L | R | V | I | G | R | G | S | Y | A | K | V | L | L | V | R | L | K | K | T | . |
. |
. |
. |
D | R | I | Y | A | M | K | V | V | K | K | E | L | V | N | D | D | E | D | I | D | W | V | Q | T | E | K | H | V | F | E | Q | A | S | N | H | P | F | L | V | G | L | H | S | C | F | Q | T |
| Template Known Secondary structure |   |
|
| S | T | T |  |  |  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  | T | T | T | . | . | . | . |
|
|  |  |  |  |  |  |  |  | G | G | G |
|
| S | T | T | T |  |  |  |  |  |  |  |  |  |  |  | T | T | T | T | S | S | T | T | B |
|
|  |  |  |  |
| B |
|
| Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
| . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | |
|
|
|
. | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . |
|   |
|   |   |
290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
K | E | P | I | M | I | V | M | E | F | C | D | G | K | S | L | E | D | A | L | L | S | K | E | E | K | V | S | A | E | D | K | I | L | Y | L | F | H | A | A | C | G | I | D | Y | L | H | G | K | Q | V | I | H | R | D | I | A | A | R | N | C | L | L | N | S | K | K | I | L | K | I | S | D | F | G | L | S | V | K | G |
| Query Conservation |   |
  |   |   |   |   |
|
|   |
|   |   |   |   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |
|
|
|   |   |   |
|
|
|
|
|
|
|
|   |
|
|
|
|   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |
|   |   |   |
| Template Sequence |   |
E | S | R | L | F | F | V | I | E | Y | V | N | G | G | D | L | M | F | H | M | Q | . |
R | Q | R | K | L | P | E | E | H | A | R | F | Y | S | A | E | I | S | L | A | L | N | Y | L | H | E | R | G | I | I | Y | R | D | L | K | L | D | N | V | L | L | D | S | E | G | H | I | K | L | T | D | Y | G | M | C | K | E | G |
| Template Known Secondary structure |   |
S | S |  |  |  |  |  |  |  |
|
|
| S |
| B |  |  |  |  |  |  | . | T | T | S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| B |
|
|
|
|
| G | G | G |  |  |  |
| T | T | S |
|  |  |  |
|
|
| T | T |
| B |
|
|
| Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
316 | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | |
. | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . |
|   |
|   |   |
370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
V | A | I | K | E | R | K | G | G | C | L | P | V | K | Y | M | A | P | E | T | L | K | K | G | L | Y | S | T | A | S | D | I | Y | S | Y | G | A | L | M | Y | E | V | Y | T | D | G | K | T | P | F | E | T | C | G | L | R | G | N | E | L | R | K | A | I | I | G | K | R | I | S | L | A | V | E | V | E | L | P | V | F |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |
|   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|   |   |
|   |
|
|   |
|   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|   |
|
|
|
|   |
| . |
|   |   |
|
| . | . |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   | . | . |   |   |   |   |   |   |
|   |   |
| Template Sequence |   |
L | R | P | G | D | T | T | S | F | C | G | T | P | N | Y | I | A | P | E | I | L | R | G | E | D | Y | G | F | S | V | D | W | W | A | L | G | V | L | M | F | E | M | M | A | . |
G | R | S | P | F | . |
. |
D | Q | N | T | E | D | Y | L | F | Q | V | I | L | E | K | Q | I | . |
. |
R | I | P | R | S | M | S | V | K |
| Template Known Secondary structure |   |
|
| T | T |
|
| B |
|
|
| S |
| G | G | G |
|
|  |  |  |  | T | T |
|
| B |
| T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
| S |
| . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . |
|
|
| T | T | S |
|  |  |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
| . |
|
|
|
|
| . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
| . | . |
|
|
|
|
|
|
|  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
395 | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | |
. | 440 | . | . | . | |
|
. | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | |
|
. | . | . | . | . | . | . | . | . |
|   |
|   |   |
450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | |
|
. | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  | . | . |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
I | A | N | I | F | E | Q | S | R | Q | Y | E | T | E | D | R | I | S | S | K | Q | I | . |
. |
I | Q | I | F | K | E | E | V | G | F | H | E | I | E | T | S | G | I |
| Query Conservation |   |
|   |   |
|
|   |   |   |
|   |   |   |
|   |   |
|
|
|   |   |
|
| . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |
|
|
|   |   |
|
|   |   |
|
|   |   |
|
|
|
|   |   |   |   |   |   |   |
|
|
|   |
|
|   |   |   |   |   |   |   |   |   |
|
| Template Sequence |   |
A | A | S | V | L | K | S | F | L | N | K | D | P | K | E | R | L | G | C | L | P | Q | T | G | F | A | D | I | Q | G | H | P | F | F | R | N | V | D | W | D | M | M |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  | T |
| S | S | S | T | T | S | T | T | T | S | T | T | T |  |  |  |  |  |  |  | S | G | G | G | S | S |
|
|  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |
|
|
|
|  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . |
|   |