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Job DescriptionO01798
Confidence100.00%DateFri May 3 21:22:31 BST 2013
Rank2Aligned Residues386
% Identity31%Templatec1oplA_
PDB info PDB header:transferaseChain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase; PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase
Resolution3.42 Å
Model Dimensions (Å)X:69.348 Y:71.477 Z:58.214

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
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   97..100.........110.........120......... 130.........140.........150.........160.........170....
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Query Sequence  VPSDEVGRVENNIDNFPFYHGFMGRNECEAMLS. . NHGDFLIRMTEIGKRVAYVISIKWKYQNIHVLVKRTKTKKLYWTK
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Template Sequence  VPSNYITP. VNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESE. SSPGQRSISLRYEGRVYHYRINTASDGKLYVSS
Template Known Secondary structure  GGG.SSSGGGSTT

GGG

TT
S.SSTT
TT

TTS
SST
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   130....... ..140.........150.........160.........170.... .....180.........190.........200.......
 
   175....180.........190.........200..... ....210.........220.........230.........240...
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Query Sequence  KYAFKSICELIAYHKRNHKPIYEGMTLICGL. . . . . . . . . . . ARHGWQLNNEQVTLNKKLGEGQFGEVHKGSLKTSVFAA
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Template Sequence  ESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKY. . . .
Template Known Secondary structure  TS
BSSTT

TTSSS






S



SSS
SSSS

B

GGGSGGGTTSSGGG....
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   208.210.........220.........230.........240.........250.........260.........270.........280...
 
   244.....250.........260.........270.........280.........290.........300.........310.... .....320..
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Query Sequence  PVTVAVKTLHQNHLSANEKILFLREANVMLTLSHPNVIKFYGVCTMKEPIMIVMEFCDGKSLEDALLSKEE. KVSAEDKI
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Template Sequence  SLTVAVKTLKEDTMEVEE. . . FLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLL
Template Known Secondary structure  T

SSSS
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   284.....290.........300. ........310.........320.........330.........340.........350.........360
 
   323......330.........340.........350.........360....... ..370.........380.........390.........400
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Query Sequence  LYLFHAACGIDYLHGKQVIHRDIAARNCLLNSKKILKISDFGLSV. . KGVAIKERKGGCLPVKYMAPETLKKGLYSTASD
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Template Sequence  YMATQISSAMEYLEKKNFIHRNLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSD
Template Known Secondary structure  TT
S

SGGG
GGG


TT


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   361........370.........380.........390.........400.........410.........420.........430.........440
 
   401........410.........420.........430.........440.........450.........460.........470.........480
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Query Sequence  IYSYGALMYEVYTDGKTPFETCGLRGNELRKAIIGKRISLAVEVELPVFIANIFEQSRQYETEDRISSKQIIQIFKEEVG
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Template Sequence  VWAFGVLLWEIATYGMSPY. . PGIDLSQVYELLEKD. YRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETM. .
Template Known Secondary structure  TTS

SS..TT

TTTTT.





TT

T
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   441........450......... 460.........470.... .....480.........490.........500.........510.....
 
   481........490......
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Query Sequence  FHEIETSGILHKLVNS
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Template Sequence  FQESSISDEVEKELGK
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SSS

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   516...520.........530.
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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