Email l.a.kelley@imperial.ac.uk Description Q18204 Date Sat Apr 13 12:59:27 BST 2013 Unique Job ID 8d9382dba279366a

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c1griA_ 100.0 17 PDB header:signal transduction adaptor Chain: A: PDB Molecule:growth factor bound protein 2; PDBTitle: grb2 2 c2lqnA_ 100.0 20 PDB header:signaling protein Chain: A: PDB Molecule:crk-like protein; PDBTitle: solution structure of crkl 3 c2l3sA_ 100.0 16 PDB header:structural protein Chain: A: PDB Molecule:autoinhibited crk protein; PDBTitle: structure of the autoinhibited crk 4 c2eyzA_ 100.0 14 PDB header:signaling protein Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog PDBTitle: ct10-regulated kinase isoform ii 5 c1ng2A_ 100.0 13 PDB header:oxidoreductase activator Chain: A: PDB Molecule:neutrophil cytosolic factor 1; PDBTitle: structure of autoinhibited p47phox 6 c1ov3A_ 100.0 13 PDB header:oxidoreductase activator Chain: A: PDB Molecule:neutrophil cytosol factor 1; PDBTitle: structure of the p22phox-p47phox complex 7 c1mv3A_ 99.9 11 PDB header:endocytosis/exocytosis Chain: A: PDB Molecule:myc box dependent interacting protein 1; PDBTitle: nmr structure of the tumor suppressor bin1: alternative2 splicing in melanoma and interaction with c-myc 8 d1udla_ 99.8 22 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 9 c2rqrA_ 99.8 12 PDB header:protein binding Chain: A: PDB Molecule:engulfment and cell motility protein 1, linker, dedicator PDBTitle: the solution structure of human dock2 sh3 domain - elmo1 peptide2 chimera complex 10 c2oi3A_ 99.8 18 PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: nmr structure analysis of the hematopoetic cell kinase sh32 domain complexed with an artificial high affinity ligand3 (pd1) 11 d1ng2a2 99.8 11 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 12 c2yt6A_ 99.8 20 PDB header:cell cycle Chain: A: PDB Molecule:adult male urinary bladder cdna, riken full- PDBTitle: solution structure of the sh3_1 domain of yamaguchi sarcoma2 viral (v-yes) oncogene homolog 1 13 c2yupA_ 99.8 19 PDB header:cell adhesion Chain: A: PDB Molecule:vinexin; PDBTitle: solution structure of the second sh3 domain of human vinexin 14 c2kymA_ 99.8 19 PDB header:signaling protein Chain: A: PDB Molecule:bud emergence protein 1; PDBTitle: solution structure of the bem1p sh3-ci domain from l.elongisporus in2 complex with ste20p peptide 15 c3nmzD_ 99.8 16 PDB header:cell adhesion/cell cycle Chain: D: PDB Molecule:rho guanine nucleotide exchange factor 4; PDBTitle: crytal structure of apc complexed with asef 16 c1x43A_ 99.8 15 PDB header:endocytosis/exocytosis Chain: A: PDB Molecule:sh3 domain grb2-like protein b1; PDBTitle: solution structure of the sh3 domain of endophilin b12 (sh3g1b1) 17 c2cudA_ 99.8 15 PDB header:signaling protein Chain: A: PDB Molecule:src-like-adapter; PDBTitle: solution structure of the sh3 domain of the human src-like2 adopter protein (slap) 18 c1x6gA_ 99.8 9 PDB header:signaling protein Chain: A: PDB Molecule:megakaryocyte-associated tyrosine-protein kinase; PDBTitle: solution structures of the sh3 domain of human2 megakaryocyte-associated tyrosine-protein kinase. 19 c2fpeB_ 99.8 16 PDB header:signaling protein Chain: B: PDB Molecule:c-jun-amino-terminal kinase interacting protein PDBTitle: conserved dimerization of the ib1 src-homology 3 domain 20 c2d8hA_ 99.8 16 PDB header:unknown function Chain: A: PDB Molecule:sh3yl1 protein; PDBTitle: solution structure of the sh3 domain of hypothetical2 protein sh3yl1 21 d1wiea_ not modelled 99.8 15 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 22 c2lcsA_ not modelled 99.8 17 PDB header:transferase, signaling protein Chain: A: PDB Molecule:nap1-binding protein 2; PDBTitle: yeast nbp2p sh3 domain in complex with a peptide from ste20p 23 d1k9aa1 not modelled 99.8 16 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 24 c2dybA_ not modelled 99.8 14 PDB header:oxidoreductase Chain: A: PDB Molecule:neutrophil cytosol factor 4; PDBTitle: the crystal structure of human p40(phox) 25 c2ct4A_ not modelled 99.8 16 PDB header:signaling protein Chain: A: PDB Molecule:cdc42-interacting protein 4; PDBTitle: solution strutcure of the sh3 domain of the cdc42-2 interacting protein 4 26 c1x6bA_ not modelled 99.8 13 PDB header:signaling protein Chain: A: PDB Molecule:rho guanine exchange factor (gef) 16; PDBTitle: solution structures of the sh3 domain of human rho guanine2 exchange factor (gef) 16 27 c1wx6A_ not modelled 99.8 20 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:cytoplasmic protein nck2; PDBTitle: solution structure of the sh3 domain of the human2 cytoplasmic protein nck2 28 c1x2qA_ not modelled 99.8 16 PDB header:signaling protein Chain: A: PDB Molecule:signal transducing adapter molecule 2; PDBTitle: solution structure of the sh3 domain of the signal2 transducing adaptor molecule 2 29 d1ue9a_ not modelled 99.8 18 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 30 c2enmA_ not modelled 99.8 21 PDB header:endocytosis Chain: A: PDB Molecule:sorting nexin-9; PDBTitle: solution structure of the sh3 domain from mouse sorting2 nexin-9 31 d1spka_ not modelled 99.8 15 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 32 c2dlpA_ not modelled 99.7 16 PDB header:structural protein Chain: A: PDB Molecule:kiaa1783 protein; PDBTitle: solution structure of the sh3 domain of human kiaa17832 protein 33 c2dx1A_ not modelled 99.7 16 PDB header:signaling protein Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 4; PDBTitle: crystal structure of rhogef protein asef 34 c2ct3A_ not modelled 99.7 16 PDB header:signaling protein Chain: A: PDB Molecule:vinexin; PDBTitle: solution structure of the sh3 domain of the vinexin protein 35 c2jteA_ not modelled 99.7 21 PDB header:signaling protein Chain: A: PDB Molecule:cd2-associated protein; PDBTitle: third sh3 domain of cd2ap 36 c2e5kA_ not modelled 99.7 16 PDB header:protein binding Chain: A: PDB Molecule:suppressor of t-cell receptor signaling 1; PDBTitle: solution structure of sh3 domain in suppressor of t-cell2 receptor signaling 1 37 c2dl5A_ not modelled 99.7 17 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:kiaa0769 protein; PDBTitle: solution structure of the first sh3 domain of human2 kiaa0769 protein 38 c2j06B_ not modelled 99.7 16 PDB header:signal transduction Chain: B: PDB Molecule:ras gtpase-activating protein 1; PDBTitle: crystal structure of the rasgap sh3 domain at 1.8 angstrom2 resolution 39 d1uffa_ not modelled 99.7 17 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 40 c1yn8E_ not modelled 99.7 17 PDB header:unknown function Chain: E: PDB Molecule:nap1-binding protein 2; PDBTitle: sh3 domain of yeast nbp2 41 c3rnjA_ not modelled 99.7 13 PDB header:protein binding Chain: A: PDB Molecule:brain-specific angiogenesis inhibitor 1-associated protein PDBTitle: crystal structure of the sh3 domain from irsp53 (baiap2) 42 c1zukA_ not modelled 99.7 17 PDB header:contractile protein Chain: A: PDB Molecule:myosin tail region-interacting protein mti1; PDBTitle: yeast bbc1 sh3 domain complexed with a peptide from las17 43 c2ed0A_ not modelled 99.7 16 PDB header:signaling protein Chain: A: PDB Molecule:abl interactor 2; PDBTitle: solution structure of the sh3 domain of abl interactor 22 (abelson interactor 2) 44 c4afzC_ not modelled 99.7 18 PDB header:hydrolase/de novo protein Chain: C: PDB Molecule:fynomer; PDBTitle: human chymase - fynomer complex 45 d1phta_ not modelled 99.7 14 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 46 c2kt1A_ not modelled 99.7 22 PDB header:protein binding Chain: A: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit PDBTitle: solution nmr structure of the sh3 domain from the p85beta2 subunit of phosphatidylinositol 3-kinase from h.sapiens,3 northeast structural genomics consortium target hr5531e 47 c2eczA_ not modelled 99.7 17 PDB header:signaling protein Chain: A: PDB Molecule:sorbin and sh3 domain-containing protein 1; PDBTitle: solution structure of the sh3 domain of sorbin and sh32 domain-containing protein 1 48 c2jxbA_ not modelled 99.7 13 PDB header:signaling protein complex Chain: A: PDB Molecule:t-cell surface glycoprotein cd3 epsilon chain, PDBTitle: structure of cd3epsilon-nck2 first sh3 domain complex 49 d1jo8a_ not modelled 99.7 20 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 50 c2yunA_ not modelled 99.7 14 PDB header:protein transport Chain: A: PDB Molecule:nostrin; PDBTitle: solution structure of the sh3 domain of human nostrin 51 c2cubA_ not modelled 99.7 15 PDB header:signaling protein Chain: A: PDB Molecule:cytoplasmic protein nck1; PDBTitle: solution structure of the sh3 domain of the human2 cytoplasmic protein nck1 52 c2m0yA_ not modelled 99.7 11 PDB header:apoptosis Chain: A: PDB Molecule:dedicator of cytokinesis protein 1; PDBTitle: solution structure of the sh3 domain of dock180 53 c2cucA_ not modelled 99.7 22 PDB header:signaling protein Chain: A: PDB Molecule:sh3 domain containing ring finger 2; PDBTitle: solution structure of the sh3 domain of the mouse2 hypothetical protein sh3rf2 54 d1arka_ not modelled 99.7 10 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 55 c2ysqA_ not modelled 99.7 21 PDB header:signaling protein Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 9; PDBTitle: solution structure of the sh3 domain from rho guanine2 nucleotide exchange factor 9 56 c2lj0A_ not modelled 99.7 13 PDB header:signaling protein Chain: A: PDB Molecule:sorbin and sh3 domain-containing protein 1; PDBTitle: the third sh3 domain of r85fl 57 c2ed1A_ not modelled 99.7 19 PDB header:signaling protein Chain: A: PDB Molecule:130 kda phosphatidylinositol 4,5-biphosphate- PDBTitle: solution structure of the sh3 domain of 130 kda2 phosphatidylinositol 4,5-biphosphate-dependent arf1 gtpase-3 activating protein 58 c3jv3A_ not modelled 99.7 20 PDB header:protein binding Chain: A: PDB Molecule:intersectin-1; PDBTitle: structure of sh3e-dh unit of murine intersectin-1l 59 c2yuoA_ not modelled 99.7 13 PDB header:signaling protein Chain: A: PDB Molecule:run and tbc1 domain containing 3; PDBTitle: solution structure of the sh3 domain of mouse run and tbc12 domain containing 3 60 d1ov3a2 not modelled 99.7 12 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 61 c2csqA_ not modelled 99.7 16 PDB header:endocytosis/exocytosis Chain: A: PDB Molecule:rim binding protein 2; PDBTitle: solution structure of the second sh3 domain of human rim-2 binding protein 2 62 c2i0nA_ not modelled 99.7 11 PDB header:structural protein Chain: A: PDB Molecule:class vii unconventional myosin; PDBTitle: structure of dictyostelium discoideum myosin vii sh3 domain2 with adjacent proline rich region 63 c1zuyB_ not modelled 99.7 20 PDB header:contractile protein Chain: B: PDB Molecule:myosin-5 isoform; PDBTitle: high-resolution structure of yeast myo5 sh3 domain 64 c2ekhA_ not modelled 99.7 9 PDB header:signaling protein Chain: A: PDB Molecule:sh3 and px domain-containing protein 2a; PDBTitle: solution structures of the sh3 domain of human kiaa0418 65 c2dmoA_ not modelled 99.7 18 PDB header:signaling protein Chain: A: PDB Molecule:neutrophil cytosol factor 2; PDBTitle: refined solution structure of the 1st sh3 domain from human2 neutrophil cytosol factor 2 (ncf-2) 66 c2djqA_ not modelled 99.7 17 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:sh3 domain containing ring finger 2; PDBTitle: the solution structure of the first sh3 domain of mouse sh32 domain containing ring finger 2 67 d1fmka1 not modelled 99.7 20 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 68 c2epdA_ not modelled 99.7 21 PDB header:protein binding Chain: A: PDB Molecule:rho gtpase-activating protein 4; PDBTitle: solution structure of sh3 domain in rho-gtpase-activating2 protein 4 69 c2rqvA_ not modelled 99.7 19 PDB header:signaling protein Chain: A: PDB Molecule:bud emergence protein 1; PDBTitle: solution structure of sh3ci domain of bem1p 70 c1x69A_ not modelled 99.7 14 PDB header:signaling protein Chain: A: PDB Molecule:cortactin isoform a; PDBTitle: solution structures of the sh3 domain of human src2 substrate cortactin 71 c2dbmA_ not modelled 99.7 17 PDB header:transferase, signaling protein Chain: A: PDB Molecule:sh3-containing grb2-like protein 2; PDBTitle: solution structures of the sh3 domain of human sh3-2 containing grb2-like protein 2 72 d1cska_ not modelled 99.7 18 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 73 c2azsA_ not modelled 99.7 19 PDB header:signaling protein Chain: A: PDB Molecule:sh2-sh3 adapter protein drk; PDBTitle: nmr structure of the n-terminal sh3 domain of drk2 (calculated without noe restraints) 74 c3qwyA_ not modelled 99.7 14 PDB header:signaling protein Chain: A: PDB Molecule:cell death abnormality protein 2; PDBTitle: ced-2 75 c2dl4A_ not modelled 99.7 22 PDB header:signaling protein Chain: A: PDB Molecule:protein stac; PDBTitle: solution structure of the first sh3 domain of stac protein 76 c2df6A_ not modelled 99.7 16 PDB header:signaling protein Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 7; PDBTitle: crystal structure of the sh3 domain of betapix in complex2 with a high affinity peptide from pak2 77 c1z9zA_ not modelled 99.7 21 PDB header:structural protein Chain: A: PDB Molecule:cytoskeleton assembly control protein sla1; PDBTitle: crystal structure of yeast sla1 sh3 domain 3 78 c2egeA_ not modelled 99.7 11 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein kiaa1666; PDBTitle: solution structure of the third sh3 domain from human2 kiaa1666 protein 79 c2eyxA_ not modelled 99.7 19 PDB header:signaling protein Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog PDBTitle: c-terminal sh3 domain of ct10-regulated kinase 80 c2ebpA_ not modelled 99.7 15 PDB header:cell adhesion Chain: A: PDB Molecule:sam and sh3 domain-containing protein 1; PDBTitle: solution structure of the sh3 domain from human sam and sh32 domain containing protein 1 81 c3qwxX_ not modelled 99.7 19 PDB header:signaling protein Chain: X: PDB Molecule:cell death abnormality protein 2; PDBTitle: ced-2 1-174 82 c2lx7A_ not modelled 99.7 26 PDB header:protein binding Chain: A: PDB Molecule:growth arrest-specific protein 7; PDBTitle: solution nmr structure of sh3 domain of growth arrest-specific protein2 7 (gas7) (fragment 1-60) from homo sapiens, northeast structural3 genomics consortium (nesg) target hr8574a 83 c2eqiA_ not modelled 99.7 13 PDB header:immune system, hydrolase Chain: A: PDB Molecule:phospholipase c, gamma 2; PDBTitle: solution structure of the sh3 domain from phospholipase c,2 gamma 2 84 c2nwmA_ not modelled 99.7 20 PDB header:cell adhesion Chain: A: PDB Molecule:vinexin; PDBTitle: solution structure of the first sh3 domain of human vinexin2 and its interaction with the peptides from vinculin 85 c4glmD_ not modelled 99.7 22 PDB header:signaling protein Chain: D: PDB Molecule:dynamin-binding protein; PDBTitle: crystal structure of the sh3 domain of dnmbp protein [homo sapiens] 86 c2dl8A_ not modelled 99.7 18 PDB header:signaling protein Chain: A: PDB Molecule:slit-robo rho gtpase-activating protein 2; PDBTitle: solution structure of the sh3 domain of human slit-robo rho2 gtpase-activating protein 2 87 c4esrB_ not modelled 99.7 19 PDB header:protein binding Chain: B: PDB Molecule:jouberin; PDBTitle: molecular and structural characterization of the sh3 domain of ahi-12 in regulation of cellular resistance of bcr-abl+ chronic myeloid3 leukemia cells to tyrosine kinase inhibitors 88 d1k4us_ not modelled 99.7 20 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 89 d1uj0a_ not modelled 99.7 18 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 90 c2l0aA_ not modelled 99.7 18 PDB header:signaling protein Chain: A: PDB Molecule:signal transducing adapter molecule 1; PDBTitle: solution nmr structure of signal transducing adapter molecule 1 stam-12 from homo sapiens, northeast structural genomics consortium target3 hr4479e 91 d2iima1 not modelled 99.7 20 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 92 c2dl3A_ not modelled 99.7 11 PDB header:cell adhesion, signaling protein Chain: A: PDB Molecule:sorbin and sh3 domain-containing protein 1; PDBTitle: solution structure of the first sh3 domain of human sorbin2 and sh3 domain-containing protein 1 93 c2xmfA_ not modelled 99.7 15 PDB header:motor protein Chain: A: PDB Molecule:myosin 1e sh3; PDBTitle: myosin 1e sh3 94 d1jqqa_ not modelled 99.7 18 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 95 c2d1xD_ not modelled 99.7 16 PDB header:cell invasion Chain: D: PDB Molecule:cortactin isoform a; PDBTitle: the crystal structure of the cortactin-sh3 domain and amap1-2 peptide complex 96 c2pqhA_ not modelled 99.7 22 PDB header:structural protein Chain: A: PDB Molecule:spectrin alpha chain, brain; PDBTitle: structure of sh3 chimera with a type ii ligand linked to the chain c-2 terminal 97 c1s1nA_ not modelled 99.7 23 PDB header:cell adhesion Chain: A: PDB Molecule:nephrocystin 1; PDBTitle: sh3 domain of human nephrocystin 98 c2bz8B_ not modelled 99.7 20 PDB header:sh3 domain Chain: B: PDB Molecule:sh3-domain kinase binding protein 1; PDBTitle: n-terminal sh3 domain of cin85 bound to cbl-b peptide 99 d1gria2 not modelled 99.7 15 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 100 d1qcfa1 not modelled 99.7 19 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 101 c2eyyA_ not modelled 99.7 20 PDB header:signaling protein Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog PDBTitle: ct10-regulated kinase isoform i 102 d1wlpb2 not modelled 99.7 11 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 103 c2dm1A_ not modelled 99.7 17 PDB header:signaling protein Chain: A: PDB Molecule:protein vav-2; PDBTitle: solution structure of the second sh3 domain of human2 protein vav-2 104 c2creA_ not modelled 99.7 9 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hef-like protein; PDBTitle: solution structure of rsgi ruh-036, an sh3 domain from2 human cdna 105 d1ugva_ not modelled 99.7 10 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 106 c3cqtA_ not modelled 99.7 20 PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fyn; PDBTitle: n53i v55l mutant of fyn sh3 domain 107 d1utia_ not modelled 99.7 18 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 108 d1zuua1 not modelled 99.7 16 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 109 d1pwta_ not modelled 99.7 22 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 110 d1y57a1 not modelled 99.7 22 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 111 c2dilA_ not modelled 99.7 14 PDB header:cell adhesion Chain: A: PDB Molecule:proline-serine-threonine phosphatase-interacting PDBTitle: solution structure of the sh3 domain of the human proline-2 serine-threonine phosphatase-interacting protein 1 112 c1w70A_ not modelled 99.7 25 PDB header:sh3 domain Chain: A: PDB Molecule:neutrophil cytosol factor 4; PDBTitle: sh3 domain of p40phox complexed with c-terminal polyproline2 region of p47phox 113 c1wi7A_ not modelled 99.7 16 PDB header:protein binding Chain: A: PDB Molecule:sh3-domain kinase binding protein 1; PDBTitle: solution structure of the sh3 domain of sh3-domain kinase2 binding protein 1 114 c2egaA_ not modelled 99.7 17 PDB header:signaling protein Chain: A: PDB Molecule:sh3 and px domain-containing protein 2a; PDBTitle: solution structure of the first sh3 domain from human2 kiaa0418 protein 115 d1uhca_ not modelled 99.7 17 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 116 c1x27F_ not modelled 99.7 22 PDB header:signaling protein Chain: F: PDB Molecule:proto-oncogene tyrosine-protein kinase lck; PDBTitle: crystal structure of lck sh2-sh3 with sh2 binding site of2 p130cas 117 d1uuea_ not modelled 99.7 24 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 118 d1u5sa1 not modelled 99.7 22 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 119 c2k6dA_ not modelled 99.7 20 PDB header:sh3 domain/ubiquitin Chain: A: PDB Molecule:sh3 domain-containing kinase-binding protein 1; PDBTitle: cin85 sh3-c domain in complex with ubiquitin 120 c2dnuA_ not modelled 99.7 17 PDB header:structural genomics, structural protein Chain: A: PDB Molecule:sh3 multiple domains 1; PDBTitle: solution structure of rsgi ruh-061, a sh3 domain from human