|   |   |
224 | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . |
| Predicted Secondary structure |   |
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
R | V | L | Y | L | E | E | P | L | F | N | T | F | I | E | A | D | L | F | V | D | R | F | E | I | I | R | R | P | I | N | P | R | E | S | M | E | K | T | G | I | S | E | E | F | D | R | L | S | Q | E | A | L | P | A | E | Q | Y | L | S | K | R | E | G | R | R | P | V | N | A | E | K | N | R | Y | K | N | I | V | P |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |   |
|
|
|
|   |
|
|
|
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |   |
|
|   |
|
| Template Sequence |   |
A | V | L | P | V | V | K | V | L | P | S | G | K | Y | T | G | A | N | L | K | S | V | I | R | V | L | R | G | L | . |
. |
. |
. |
. |
. |
L | D | Q | G | I | P | S | K | E | L | E | N | L | Q | E | L | K | P | L | D | Q | . |
. |
. |
. |
C | L | I | G | Q | T | K | E | N | R | R | K | N | R | Y | K | N | I | L | P |
| Template Known Secondary structure |   |
 | T | S |
| S | S |
|
|
| S | S | S | T | T | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . |  |  | T | T |  |  |  |  |  |  |  |  |  | T | T |
|
|
| S | S |
| . | . | . | . |
|
| G | G | G | S |  |  |  |  | T | T |
| S | S | T | T |
|
|
|
| Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . |
|
|  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
2179 | 2180 | . | . | . | . | . | . | . | . | . | 2190 | . | . | . | . | . | . | . | . | . | 2200 | . | . | . | . | . | . | . | |
|
|
|
|
|
. | . | 2210 | . | . | . | . | . | . | . | . | . | 2220 | . | . | . | . | . | . | . | . | |
|
|
|
. | 2230 | . | . | . | . | . | . | . | . | . | 2240 | . | . | . | . | . | . | . | . |
|   |
|   |   |
304 | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | |
. |
| Predicted Secondary structure |   |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
| . |
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
| Query Sequence |   |
F | D | H | T | R | V | I | L | T | D | R | P | N | T | P | G | S | D | Y | I | N | A | S | Y | V | R | F | E | N | S | Q | R | T | K | N | V | T | F | A | C | E | K | S | F | I | A | T | Q | G | C | L | E | T | T | I | S | D | F | W | S | M | V | W | Q | E | N | S | R | V | I | V | M | P | T | M | E | N | E | . |
R |
| Query Conservation |   |
|
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|
|
|
|
|
|
|
|   |   |
|
|   |
|
|
|
|
|
|
|
|
|
|
|   |
|
|
|
|
|
|   |   |   |
| . |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
| Template Conservation |   |
  |
|   |   |
|
|   |
|   | . | . | . | . | . |   |   |   |
|
|
|
|
|
|   |
|   |   |   | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
|
|   |
|
|   |
|
|   |   |
|   |   |
|
|
|   |
|
|   |
|   |   |   |   |   |
|
|
|
|
|   |   |   |
|   |   |
| Template Sequence |   |
Y | D | A | T | R | V | P | L | G | . |
. |
. |
. |
. |
D | E | G | G | Y | I | N | A | S | F | I | K | I | P | . |
. |
. |
. |
. |
. |
. |
. |
V | G | K | E | E | F | V | Y | I | A | C | Q | G | P | L | P | T | T | V | G | D | F | W | Q | M | I | W | E | Q | K | S | T | V | I | A | M | M | T | Q | E | V | E | G | E |
| Template Known Secondary structure |   |
| S | T | T | B |
|
| B | T | . | . | . | . | . | T | T | T | B |
|
| S |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . |  | T | T |  |  |  |  |  |  |  |  |
|
|
|
| G | G | G |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |
| S |
| S |  |  | T | T |
| Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|  |  |  |
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
2249 | 2250 | . | . | . | . | . | . | . | |
|
|
|
|
. | . | 2260 | . | . | . | . | . | . | . | . | . | 2270 | . | |
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 2280 | . | . | . | . | . | . | . | . | . | 2290 | . | . | . | . | . | . | . | . | . | 2300 | . | . | . | . | . | . | . | . | . | 2310 | . | . | . | . | . |
|   |
|   |   |
383 | . | . | . | . | . | . | 390 | . | . | . | . | . | |
. | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | |
|
. |
| Predicted Secondary structure |   |
|  |  |
|
|
|
|
|
|
|
|
|
| . |
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  | . | . |
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
| Query Sequence |   |
K | E | K | C | A | R | Y | W | P | A | E | V | N | . |
K | P | E | V | H | G | D | I | S | L | T | C | T | I | E | R | K | V | Q | R | A | V | S | D | E | V | K | A | E | L | E | Q | E | K | T | N | R | I | A | K | G | L | V | P | E | A | E | L | N | G | D | G | I | S | Y | I | L | R | T | L | V | M | K | . |
. |
K |
| Query Conservation |   |
  |   |
|
|   |   |
|
|
|   |
|   |   | . |   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |
|   | . | . |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . | . |
|
| Template Conservation |   |
  |   |
|
|   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |
|   |
|   |
|   |   |   |   |
| Template Sequence |   |
K | I | K | C | Q | R | Y | W | P | N | I | L | G | K | T | T | M | V | S | N | R | L | R | L | A | L | V | R | M | Q | Q | L | K | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | F | V | V | R | A | M | T | L | E | D | I | Q |
| Template Known Secondary structure |   |
 |  |
|
|
|
|
| S |
| S | S | T | T |
|
|  |  | S | S | S | S |  |  |  |  |  |  |  |  |  |  |
| S | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | S |  |  |  |  |  |  |  |  |  |  | T | T |
| Template Predicted Secondary structure |   |
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
2316 | . | . | . | 2320 | . | . | . | . | . | . | . | . | . | 2330 | . | . | . | . | . | . | . | . | . | 2340 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | 2350 | . | . | . | . | . | . | . | . | . | 2360 | . |
|   |
|   |   |
460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
G | K | D | T | R | E | I | R | Q | L | Q | Y | L | T | W | P | D | H | G | C | P | L | H | P | Y | A | V | L | N | F | L | E | D | V | D | R | E | Y | D | Y | F | N | A | Q | P | I | A | A | S | L | P | Q | G | P | I | V | V | H | C | S | A | G | I | G | R | T | G | T | V | L | V | L | D | A | L | L | N | Q | V | K |
| Query Conservation |   |
  |   |   |   |
|   |
|   |
|   |   |
|
|   |
|
|
|   |
|
|
|   |   |   |   |   |
|
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |
|
|   |
|
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |
|   |
|   |
|   |   |   |   |   |
|
|
|   |
|   |
|   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|
|
|
|
|
|
|   |
|   |
|
|
|
|   |
|
|
|
|
|   |   |   |   |   |
|   |
| Template Sequence |   |
T | R | E | V | R | H | I | S | H | L | N | F | T | A | W | P | D | H | D | T | P | S | Q | P | D | D | L | L | T | F | I | S | Y | M | R | H | I | H | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | G | P | I | I | T | H | C | S | A | G | I | G | R | S | G | T | L | I | C | I | D | V | V | L | G | L | I | S |
| Template Known Secondary structure |   |
T | T |  |  |  |  |  |  |  |  |  |  |
| S |
|
| T | T | S |
|
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . | S | S |
|  |  |  |  |
| S | S | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
2362 | . | . | . | . | . | . | . | 2370 | . | . | . | . | . | . | . | . | . | 2380 | . | . | . | . | . | . | . | . | . | 2390 | . | . | . | . | . | . | . | . | . | 2400 | |
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 2410 | . | . | . | . | . | . | . | . | . | 2420 | . | . | . | . | . | . | . | . | . |
|   |
|   |   |
540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . |
| Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
K | V | G | L | L | C | P | M | D | V | Y | K | M | V | K | Y | V | R | T | Y | R | S | G | L | V | Q | T | E | Q | Q | Y | Q | F | L | Y | K | A | L | A | F | Y | L | K | N |
| Query Conservation |   |
  |   |   |   |   |   |   |
|
|
|   |   |   |
|
|   |
|
|   |
|
|   |   |
|
|
|
|   |
|
|
|   |
|
|
|   |
|
|   |   |
|
|   |   |
| Alig confidence |   |
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   | . | . | . |   |
|
|
|   |   |   |
|   |   |
|
|   |
|
|   |   |   |
|
|
|   |   |
|
|   |
|
|
|   |   |
|
|   |   |
|   |   |
| Template Sequence |   |
Q | D | L | . |
. |
. |
D | F | D | I | S | D | L | V | R | C | M | R | L | Q | R | H | G | M | V | Q | T | E | D | Q | Y | I | F | C | Y | Q | V | I | L | Y | V | L | T | R |
| Template Known Secondary structure |   |
T | T |
| . | . | . |
|
|
|  |  |  |  |  |  |  |  |  | T | T | S | T | T |
| S |
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |
|
| . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
2430 | . | . | |
|
|
. | . | . | . | . | . | . | 2440 | . | . | . | . | . | . | . | . | . | 2450 | . | . | . | . | . | . | . | . | . | 2460 | . | . | . | . | . | . | . | . | . | 2470 |
|   |