|   |   |
234 | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
N | T | F | I | E | A | D | L | F | V | D | R | F | E | I | I | R | R | P | I | N | P | R | E | S | M | E | K | T | G | I | S | E | E | F | D | R | L | S | Q | E | A | L | P | A | E | Q | Y | L | S | K | R | E | G | R | R | P | V | N | A | E | K | N | R | Y | K | N | I | V | P | F | D | H | T | R | V | I | L | T | D |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |   |
|
|
|
|   |
|
|
|
|
|
|   |
|
|
|   |
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|
|   |   |
| . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |   |   |
|   |
|   |
|   |   |
|
|   |
|   |   |
| Template Sequence |   |
S | R | V | L | T | R | S | Q | L | R | D | V | V | A | S | S | H | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | Q | S | E | F | M | E | I | . |
. |
. |
. |
. |
. |
P | M | N | F | V | D | P | K | E | I | D | I | P | R | H | G | T | K | N | R | Y | K | T | I | L | P | N | P | L | S | R | V | C | L | R | P |
| Template Known Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  | T | T | T |  | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  | S | . | . | . | . | . | . |
|
|
|
|
|
| T | T | T |
|
|
| T | T | G | G | G | G |
| S | S | T | T |
|
|
|
| G | G | G | B |
|
|
|
|
|
| Template Predicted Secondary structure |   |
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
267 | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 290 | . | . | |
|
|
|
|
|
. | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . |
|   |
|   |   |
314 | . | . | . | . | |
. | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | |
. | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . |
| Predicted Secondary structure |   |
|
|
|
|
| . |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
R | P | N | T | P | . |
G | S | D | Y | I | N | A | S | Y | V | R | F | E | N | S | Q | R | T | K | N | V | T | F | A | . |
C | E | K | S | F | I | A | T | Q | G | C | L | E | T | T | I | S | D | F | W | S | M | V | W | Q | E | N | S | R | V | I | V | M | P | T | M | E | N | E | R | K | E | K | C | A | R | Y | W | P |
| Query Conservation |   |
  |   |   |   |   | . |   |
|
|
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   | . |   |   |
|   |
|
|
|
|
|
|
|
|   |   |
|
|   |
|
|
|
|
|
|
|
|
|
|
|   |
|
|
|
|
|
|   |   |   |
|   |   |   |
|
|   |   |
|
|
|
| Alig confidence |   |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |
|
|
|
|
|
|   |
|   | . | . | . | . | . | . | . | . | . | . |
|   |   |   |   |   |   |   |
|
|   |
|
|   |
|
|   |   |
|   |   |
|
|
|   |
|
|   |
|   |   |
|   |   |
|
|
|
|   |   |   |   |
|   |   |   |
|
|   |   |
|
|
|
| Template Sequence |   |
K | N | I | T | D | S | L | S | T | Y | I | N | A | N | Y | I | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | Y | S | G | K | E | K | A | F | I | A | T | Q | G | P | M | I | N | T | V | N | D | F | W | Q | M | V | W | Q | E | D | S | P | V | I | V | M | I | T | K | L | K | E | K | N | E | K | C | V | L | Y | W | P |
| Template Known Secondary structure |   |
T | T |
|
|
| S | G | G | G |
|
| S |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . |
| G | G | G |
| T | T | S |  |  |  |  |
|
|
|
| G | G | G |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |
| S |
| S | B | S | S | S | B |
|
|
|
|
| S |
|
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
329 | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . |
|   |
|   |   |
392 | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . |
| Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
A | E | V | N | K | P | E | V | H | G | D | I | S | L | T | C | T | I | E | R | K | V | Q | R | A | V | S | D | E | V | K | A | E | L | E | Q | E | K | T | N | R | I | A | K | G | L | V | P | E | A | E | L | N | G | D | G | I | S | Y | I | L | R | T | L | V | M | K | K | G | K | D | T | R | E | I | R | Q | L | Q | Y |
| Query Conservation |   |
  |
|   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |
|   |   |   |   |   |   |
|   |
|   |
|   |   |
|
| Alig confidence |   |
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  | . | . | . |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |
|
| Template Sequence |   |
E | . |
. |
. |
K | R | G | I | Y | G | K | V | E | V | L | V | T | G | V | T | E | C | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
N | Y | T | I | R | N | L | V | L | K | Q | G | S | H | T | Q | H | V | K | H | Y | W | Y |
| Template Known Secondary structure |   |
S | . | . | . | S |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |
| S | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | S |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
| . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
399 | |
|
|
400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . |
|   |
|   |   |
472 | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . |
| Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
L | T | W | P | D | H | G | C | P | L | H | P | Y | A | V | L | N | F | L | E | D | V | D | R | E | Y | D | Y | F | N | A | Q | P | I | A | A | S | L | P | Q | G | P | I | V | V | H | C | S | A | G | I | G | R | T | G | T | V | L | V | L | D | A | L | L | N | Q | V | K | K | V | G | L | L | C | P | M | D | V | Y | K |
| Query Conservation |   |
|   |
|
|
|   |
|
|
|   |   |   |   |   |
|
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |
|
|   |
|
|   |   |   |   |   |   |   |   |
|
|
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
| Template Conservation |   |
  |   |
|
|
|   |   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |   |   | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|
|
|
|
|
|
|   |
|   |
|
|
|
|   |
|   |
|   |
|   |   |   |   |   |
|   |   |   |   | . | . | . |   |
|
|
|   |   |
| Template Sequence |   |
T | S | W | P | D | H | K | T | P | D | S | A | Q | P | L | L | Q | L | M | L | D | V | E | E | D | R | L | . |
. |
. |
. |
. |
. |
. |
. |
A | S | E | G | R | G | P | V | V | V | H | C | S | A | G | I | G | R | T | G | C | F | I | A | T | S | I | G | C | Q | Q | L | K | E | E | G | . |
. |
. |
V | V | D | A | L | S |
| Template Known Secondary structure |   |
|
| S |
| T | T | S | S |
| S |
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | T |
| T | T | S |
|
|  |  |  |  | S | S | S | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | . | . | . |  |  |
|  |  |  |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . |
|
|
|  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
442 | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
. | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | |
|
|
. | . | . | . | . | 510 |
|   |
|   |   |
552 | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
M | V | K | Y | V | R | T | Y | R | S | G | L | V | Q | T | E | Q | Q | Y | Q | F | L | Y | K | A | L | A | F | Y | L | K | N | N | N | P | Y | P | V |
| Query Conservation |   |
  |
|
|   |
|
|   |
|
|   |   |
|
|
|
|   |
|
|
|   |
|
|
|   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|   |   |
|
|   |
|
|   |   |   |
|
|
|   |   |
|
|   |
|   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
I | V | C | Q | L | R | V | D | R | G | G | M | V | Q | T | S | E | Q | Y | E | F | V | H | H | A | L | C | L | F | E | S | R | L | S | P | E | T | V |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  | S | T | T | S | S |
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S |
|
|
|
|
|
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
511 | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . |
|   |