Job Description G5EC24 Confidence 100.00% Date Fri May 3 21:06:01 BST 2013 Rank 27 Aligned Residues 275 % Identity 38% Template c2vexA_ PDB info PDB header:hydrolase Chain: A: PDB Molecule:tyrosine-protein phosphatase non-receptor type 1; PDBTitle: crystal strucutre of protein tyrosine phosphatase 1b in2 complex with an isothiazolidinone-containing inhibitor Resolution 2.20 Å

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		242	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.
Predicted Secondary structure
Query SS confidence
Query Sequence		F	V	D	R	F	E	I	I	R	R	P	I	N	P	R	E	S	M	E	K	T	G	I	S	E	E	F	D	R	L	S	Q	E	A	L	P	A	E	Q	Y	L	S	K	R	E	G	R	R	P	V	N	A	E	K	N	R	Y	K	N	I	V	P	F	D	H	T	R	V	I	L	T	D	R	P	N	T	P	G	S	D
Query Conservation
Alig confidence												.	.	.	.	.	.	.	.	.																				.	.	.	.																																		.	.	.	.
Template Conservation												.	.	.	.	.	.	.	.	.																				.	.	.	.																																		.	.	.	.
Template Sequence		M	E	K	E	F	E	Q	I	D	K	.	.	.	.	.	.	.	.	.	S	G	S	W	A	A	I	Y	Q	D	I	R	H	E	A	S	D	F	P	.	.	.	.	C	R	V	A	K	L	P	K	N	K	N	R	N	R	Y	R	D	V	S	P	F	D	H	S	R	I	K	L	H	Q	E	D	N	.	.	.	.	D
Template Known Secondary structure												.	.	.	.	.	.	.	.	.		T													S					.	.	.	.		T	T	T	T	S	G	G	G	G	G	G		S	S	T	T					G	G	G					S		S	S		.	.	.	.
Template Predicted Secondary structure												.	.	.	.	.	.	.	.	.																				.	.	.	.																																		.	.	.	.
Template SS confidence
		3	.	.	.	.	.	.	10	.	.										.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.					.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.					.
		322	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.		.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400
Predicted Secondary structure																																																														.
Query SS confidence																																																														.
Query Sequence		Y	I	N	A	S	Y	V	R	F	E	N	S	Q	R	T	K	N	V	T	F	A	C	E	K	S	F	I	A	T	Q	G	C	L	E	T	T	I	S	D	F	W	S	M	V	W	Q	E	N	S	R	V	I	V	M	P	T	M	E	N	E	.	R	K	E	K	C	A	R	Y	W	P	A	E	V	N	K	P	E	V	H
Query Conservation																																																														.
Alig confidence										.	.	.	.	.	.	.	.	.	.																																											.
Template Conservation										.	.	.	.	.	.	.	.	.	.
Template Sequence		Y	I	N	A	S	L	I	K	.	.	.	.	.	.	.	.	.	.	M	E	E	A	Q	R	S	Y	I	L	T	Q	G	P	L	P	N	T	C	G	H	F	W	E	M	V	W	E	Q	K	S	R	G	V	V	M	L	N	R	V	M	E	K	G	S	L	K	C	A	Q	Y	W	P	Q	K	E	E	K	E	M	I	F
Template Known Secondary structure										.	.	.	.	.	.	.	.	.	.		T	T	T	T											T	T	T											T	T								S		S			T	T				S				S		S	S	T	T	S
Template Predicted Secondary structure										.	.	.	.	.	.	.	.	.	.
Template SS confidence
		66	.	.	.	70	.	.	.											.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.
		401	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.			.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.
Predicted Secondary structure																																																												.	.
Query SS confidence																																																												.	.
Query Sequence		G	D	I	S	L	T	C	T	I	E	R	K	V	Q	R	A	V	S	D	E	V	K	A	E	L	E	Q	E	K	T	N	R	I	A	K	G	L	V	P	E	A	E	L	N	G	D	G	I	S	Y	I	L	R	T	L	V	M	K	.	.	K	G	K	D	T	R	E	I	R	Q	L	Q	Y	L	T	W	P	D	H	G
Query Conservation																																																												.	.
Alig confidence																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.											.	.
Template Conservation																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		E	D	T	N	L	K	L	T	L	I	S	E	D	I	K	S	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	Y	Y	T	V	R	Q	L	E	L	E	N	L	T	T	Q	E	T	R	E	I	L	H	F	H	Y	T	T	W	P	D	F	G
Template Known Secondary structure		G	G	G	T												S	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	S											T	T	T																T	T
Template Predicted Secondary structure																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		136	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.																																	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.
		479	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		C	P	L	H	P	Y	A	V	L	N	F	L	E	D	V	D	R	E	Y	D	Y	F	N	A	Q	P	I	A	A	S	L	P	Q	G	P	I	V	V	H	C	S	A	G	I	G	R	T	G	T	V	L	V	L	D	A	L	L	N	Q	V	K	K	V	G	L	L	C	P	M	D	V	Y	K	M	V	K	Y	V	R	T
Query Conservation
Alig confidence																			.	.	.	.	.	.	.	.
Template Conservation																			.	.	.	.	.	.	.	.
Template Sequence		V	P	E	S	P	A	S	F	L	N	F	L	F	K	V	R	E	.	.	.	.	.	.	.	.	S	G	S	L	S	P	E	H	G	P	V	V	V	H	C	S	A	G	I	G	R	S	G	T	F	C	L	A	D	T	C	L	L	L	M	D	K	R	K	D	P	S	S	V	D	I	K	K	V	L	L	E	M	R	K
Template Known Secondary structure				S															.	.	.	.	.	.	.	.	T	T	T	T		T	T	S								S	S	S	S	S																		S	S		G	G	G											T	T
Template Predicted Secondary structure																			.	.	.	.	.	.	.	.
Template SS confidence
		184	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200									.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.
		559	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	R	S	G	L	V	Q	T	E	Q	Q	Y	Q	F	L	Y	K	A	L	A	F	Y	L	K	N
Query Conservation
Alig confidence
Template Conservation
Template Sequence		F	R	M	G	L	I	Q	T	A	D	Q	L	R	F	S	Y	L	A	V	I	E	G	A	K	F
Template Known Secondary structure		T	S	T	T		S		S
Template Predicted Secondary structure
Template SS confidence
		256	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D