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Job DescriptionG5EC24
Confidence100.00%DateFri May 3 21:06:01 BST 2013
Rank3Aligned Residues478
% Identity44%Templatec2shpA_
PDB info PDB header:tyrosine phosphataseChain: A: PDB Molecule:shp-2; PDBTitle: tyrosine phosphatase shp-2
Resolution2.00 Å
Model Dimensions (Å)X:82.293 Y:62.894 Z:52.908

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   8.10.........20.........30.........40.........50.........60.........70.........80.......
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Query Sequence  QYNFYYRVNGEKAEELLKEYGEDGDFLLRYSESNPQNFSISVRVAEDKILHIKVTKYESDMLSIFEDERTTPNQFGSITE
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Template Sequence  RRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDLTLSVR. RNGAVTHIKIQNT. GDYYDLYGG. . . . . EKFATLAE
Template Known Secondary structure  STTB
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TT
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   4.....10.........20.........30.........40...... ...50......... 60........ .70......
 
   88.90.........100.........110.........120.........130.........140........ .150.........160......
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Query Sequence  LAEFYMEFPEKLREKNGLFLELKKPVYVPYHLEACAEEQRRTQLYRWWHGNLPASSANKLL. QTEKNGTYLLRASQHIPG
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Template Sequence  LVQYYMEHHGQLKEKNGDVIELKYPLN. . . . . . . . . . . CADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPG
Template Known Secondary structure  T
TT
SBSSSS
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TT
TTB

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   77..80.........90.........100... ......110.........120.........130.........140.....
 
   167..170.... .....180.........190.........200.........210.........220.........230.........240.
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Query Sequence  ALVISAKT. . . . . EGQVVHLTIYQDPSTGRFNIDGDRTKFQSAWLLIDSYSKNPIVEKGEASRVLYLEEPLFNTFIEADL
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Template Sequence  DFVLSVRTGDNDGKSKVTHVMIRCQE. . LKYDVGGGE. RFDSLTDLVEHYKKNPMVET. . LGTVLQLKQPLNTTRINAAE
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T..TSSSS
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   146...150.........160.........170. ........180 .........190.........200 .........210.........220
 
   242.......250.........260.........270.........280.........290.........300.........310.........320.
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Query Sequence  FVDRFEIIRRPINPRESMEKTGISEEFDRLSQEALPAEQYLSKREGRRPVNAEKNRYKNIVPFDHTRVILTDRPNTPGSD
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Template Sequence  IESRVRELSK. . . . . . . . . . . GFWEEFETLQQQE. . CKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLH. . . . . . DSD
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GGG..GGG



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   226...230..... ....240........ .250.........260.........270.........280... ...
 
   322.......330.........340.........350.........360.........370.........380. ........390.........400
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Query Sequence  YINASYVRFENSQRTKNVTFACEKSFIATQGCLETTISDFWSMVWQENSRVIVMPTMENE. RKEKCARYWPAEVNKPEVH
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Template Sequence  YINANIIM. . . . . . . . . . . . . PKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDE. YALKEY
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TTTT


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   304.....310. ........320.........330.........340.........350.........360... ......
 
   401........410.........420.........430.........440.........450......... 460.........470.......
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Query Sequence  GDISLTCTIERKVQRAVSDEVKAELEQEKTNRIAKGLVPEAELNGDGISYILRTLVMKK. . . GKDTREIRQLQYLTWPDH
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Template Sequence  GVMRVRNVKESAAH. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . DYTLRELKLSKVGQGNTERTVWQYHFRTWPDH
Template Known Secondary structure  TT
S..................................STT



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   381........390.... .....400.........410.........420......
 
   478.480.........490.........500.........510.........520.........530.........540.........550.......
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Query Sequence  GCPLHPYAVLNFLEDVDREYDYFNAQPIAASLPQGPIVVHCSAGIGRTGTVLVLDALLNQVKKVGLLCPMDVYKMVKYVR
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Template Sequence  GVPSDPGGVLDFLEEVHHKQESIMD. . . . . . . . AGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVR
Template Known Secondary structure  S

S
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   427..430.........440.........450. ........460.........470.........480.........490........
 
   558.560.........570.........580...
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Query Sequence  TYRSGLVQTEQQYQFLYKALAFYLKN
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Template Sequence  SQRSGMVQTEAQYRSIYMAVQHYIET
Template Known Secondary structure  TTSTTSS

T
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   499500.........510.........520....
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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