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Job DescriptionG5EC24
Confidence100.00%DateFri May 3 21:06:01 BST 2013
Rank2Aligned Residues483
% Identity42%Templatec2b3oA_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type PDBTitle: crystal structure of human tyrosine phosphatase shp-1
Resolution2.80 Å
Model Dimensions (Å)X:68.653 Y:90.062 Z:48.395

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


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Query Sequence  NFYYRVNGEKAEELLKEYGEDGDFLLRYSESNPQNFSISVRVAEDKILHIKVTKYESDMLSIFEDERTTPNQFGSITELA
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Template Sequence  WFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVR. VGDQVTHIRIQNS. GDFYDLYGG. . . . . EKFATLTELV
Template Known Secondary structure  TB
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Query Sequence  EFYMEFPEKLREKNGLFLELKKPVYVPYHLEACAEEQRRTQLYRWWHGNLPASSANKLL. QTEKNGTYLLRASQHIPGAL
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Template Sequence  EYYTQQQGVLQDRDGTIIHLKYPLN. . . . . . . . . . . CSDPTSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDF
Template Known Secondary structure  TT
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   77..80.........90.........100. ........110.........120.........130.........140.....
 
   169170.... .....180.........190.........200.........210.........220.........230.........240...
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Query Sequence  VISAKT. . . . . EGQVVHLTIYQDPSTGRFNIDGDRTKFQSAWLLIDSYSKNPIVEKGEASRVLYLEEPLFNTFIEADLFV
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Template Sequence  VLSVLSDQPKSPLRVTHIKVMCEG. . GRYTVGGLE. TFDSLTDLVEHFKKTGIEEA. . SGAFVYLRQPYYATRVNAADIE
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T..TSBBSSSS
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   244.....250.........260.........270.........280.........290.........300.........310..... ....320..
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Query Sequence  DRFEIIRRPINPRESMEKTGISEEFDRLSQEALPAEQYLSKREGRRPVNAEKNRYKNIVPFDHTRVILTDRP. NTPGSDY
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Template Sequence  NR. . . . . . . . . . . . . . . . . . FWEEFESLQKQE. . VKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPGSDY
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TTT..TTT




GGGSTTGGGG
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   225. ...230........ .240.........250.........260.........270.........280....
 
   323......330.........340.........350.........360.........370.........380. ........390.........400.
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Query Sequence  INASYVRFENSQRTKNVTFACEKSFIATQGCLETTISDFWSMVWQENSRVIVMPTMENE. RKEKCARYWPAEVNKPEVHG
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Template Sequence  INANYIKNQLLG. . . . . PDENAKTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRNKCVPYWP. EVGMQRAYG
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   302.......310... ......320.........330.........340.........350.........360...... ...370.....
 
   402.......410.........420.........430.........440.........450......... 460.........470........
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Query Sequence  DISLTCTIERKVQRAVSDEVKAELEQEKTNRIAKGLVPEAELNGDGISYILRTLVMKK. . . GKDTREIRQLQYLTWPDHG
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Template Sequence  PYSVTNCGEHDTT. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . EYKLRTLQVSPLDNGDLIREIWHYQYLSWPDHG
Template Known Secondary structure  S

S..................................S
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   376...380........ .390.........400.........410.........420.
 
   479480.........490.........500.........510.........520.........530.........540.........550........
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Query Sequence  CPLHPYAVLNFLEDVDREYDYFNAQPIAASLPQGPIVVHCSAGIGRTGTVLVLDALLNQVKKVGLLCPMDVYKMVKYVRT
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Template Sequence  VPSEPGGVLSFLDQINQRQESLPH. . . . . . . . AGPIIVHCSAGIGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMVRA
Template Known Secondary structure 

SSSSTT........



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   422.......430.........440..... ....450.........460.........470.........480.........490...
 
   559560.........570.........580...
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Query Sequence  YRSGLVQTEQQYQFLYKALAFYLKN
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Template Sequence  QRSGMVQTEAQYKFIYVAIAQFIET
Template Known Secondary structure  TSTTSS
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   494.....500.........510........
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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