Job Description G5EC24 Confidence 100.00% Date Fri May 3 21:06:01 BST 2013 Rank 49 Aligned Residues 213 % Identity 23% Template c1a81E_ PDB info PDB header:complex (transferase/peptide) Chain: E: PDB Molecule:syk kinase; PDBTitle: crystal structure of the tandem sh2 domain of the syk kinase bound to2 a dually tyrosine-phosphorylated itam Resolution 3.00 Å

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		4	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.		30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.
Predicted Secondary structure																												.
Query SS confidence																												.
Query Sequence		L	A	L	R	Q	Y	N	F	Y	Y	R	V	N	G	E	K	A	E	E	L	L	K	E	Y	G	E	.	D	G	D	F	L	L	R	Y	S	E	S	N	P	Q	N	F	S	I	S	V	R	V	A	E	D	K	I	L	H	I	K	V	T	K	Y	E	S	D	M	L	S	I	F	E	D	E	R	T	T	P	N	Q	F
Query Conservation																												.
Alig confidence																												.																						.																					.	.	.	.	.
Template Conservation																																																		.																					.	.	.	.	.
Template Sequence		S	A	N	H	L	P	F	F	F	G	N	I	T	R	E	E	A	E	D	Y	L	V	Q	G	G	M	S	D	G	L	Y	L	L	R	Q	S	R	N	Y	L	G	G	F	A	L	S	V	A	.	H	G	R	K	A	H	H	Y	T	I	E	R	E	L	N	G	T	Y	A	I	.	.	.	.	.	A	G	G	R	T	H
Template Known Secondary structure			G	G	G		T	T			S	S												T	T	T			T	T								S	S	S	T	T								.		S	S	S										T	T	T					.	.	.	.	.	T	T	S			B
Template Predicted Secondary structure																																																		.																					.	.	.	.	.
Template SS confidence
		9	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.		.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.						.	.	.	80	.	.
		83	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.			.	150	.	.	.	.	.	.	.	.	.	160
Predicted Secondary structure																																																																				.	.
Query SS confidence																																																																				.	.
Query Sequence		G	S	I	T	E	L	A	E	F	Y	M	E	F	P	E	K	L	R	E	K	N	G	L	F	L	E	L	K	K	P	V	Y	V	P	Y	H	L	E	A	C	A	E	E	Q	R	R	T	Q	L	Y	R	W	W	H	G	N	L	P	A	S	S	A	N	K	L	L	.	.	Q	T	E	K	N	G	T	Y	L	L	R	A
Query Conservation																																																																				.	.
Alig confidence																																																																				.	.
Template Conservation
Template Sequence		A	S	P	A	D	L	C	H	Y	H	S	Q	E	S	D	G	L	V	C	L	L	K	K	P	F	N	R	P	Q	G	V	Q	P	K	T	P	Q	L	E	K	L	I	A	T	T	A	H	E	K	M	P	W	F	H	G	K	I	S	R	E	E	S	E	Q	I	V	L	I	G	S	K	T	N	G	K	F	L	I	R	A
Template Known Secondary structure		S	S									T	T			T	T	S	S	S				S	B					T	T															T	S	G	G	G		T	T																S	S				T	T
Template Predicted Secondary structure
Template SS confidence
		83	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.
		161	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.
Predicted Secondary structure
Query SS confidence
Query Sequence		S	Q	H	I	P	G	A	L	V	I	S	A	K	T	E	G	Q	V	V	H	L	T	I	Y	Q	D	P	S	T	G	R	F	N	I	D	G	D	R	T	K	F	Q	S	A	W	L	L	I	D	S	Y	S	K	N	P	I	V	E	K	G	E	A	S	R	V	L	Y	L	E	E	P
Query Conservation
Alig confidence			.																									.												.																	.	.	.	.	.	.
Template Conservation			.																									.												.																	.	.	.	.	.	.
Template Sequence		R	.	D	N	N	G	S	Y	A	L	C	L	L	H	E	G	K	V	L	H	Y	R	I	D	K	D	.	K	T	G	K	L	S	I	P	E	G	K	.	K	F	D	T	L	W	Q	L	V	E	H	Y	S	Y	K	A	.	.	.	.	.	.	D	G	L	L	R	V	L	T	V	P
Template Known Secondary structure			.	S	S	S	S									T	T											.	T	T	S					T	T	S		.		B	S										T	T			.	.	.	.	.	.	T	T	S	S	S				S	B
Template Predicted Secondary structure			.																									.												.																	.	.	.	.	.	.
Template SS confidence
		197		.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.		.	.	.	.	.	.	.	.	230	.	.		.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.							.	250	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D