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Job DescriptionQ22070
Confidence100.00%DateSat Apr 13 12:57:32 BST 2013
Rank8Aligned Residues237
% Identity24%Templatec2b3oA_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type PDBTitle: crystal structure of human tyrosine phosphatase shp-1
Resolution2.80 Å
Model Dimensions (Å)X:53.349 Y:79.507 Z:35.880

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
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   604.....610.........620.........630.........640.........650.........660.........670.........680...
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Query Sequence  EWFHGRCERDEAKKRILEHKEKGNGLFMIRDSNLFIGDFSLSILHDGKVHHVRIRSKIIDKEKKYYFMDNKVCDTLYELV
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Template Sequence  RWFHRDLSGLDAETLLKGRGV. . HGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGD. . . . FYDLYGGEKFATLTELV
Template Known Secondary structure  TTB
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   3......10.........20... ......30.........40.........50......... 60.........70......
 
   684.....690....... ..700.........710.........720.........730.........740.........750......
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Query Sequence  SYYTRHYLTTAHFK. . . MVLTIPCPQPQPHLNQPWFSATADKEKAEELLSLVPEDGAFLIRTSSTDSSVYVLSLKV. . . .
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Template Sequence  EYYTQQQGVLQDRDGTIIHLKYPLNCSDPT. SERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPK
Template Known Secondary structure  TT
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   77..80.........90.........100...... ...110.........120.........130.........140.........150.....
 
   757..760.........770.... .....780.........790....... ..800...... ...810.......
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Query Sequence  . DGEFWHYRLKRDGRIFVV. NQKVFENLNQIVEFYANREFVRG. . . . ISLRFPVNE. . . . . . . . . . . . . KDISHLTAELA
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Template Sequence  SPLRVTHIKVMCEGGRYTVGGLETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRFWEEFESLQKQEV
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   160.........170.........180.........190.........200.........210.........220.........230.........
 
   818.820.........830.........840.......
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Query Sequence  EARTPGCYMDLKDLDKEVQARALRPYRGTA
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Template Sequence  KNLHQRLEGQRPENKGKNRYKNILPFDHSR
Template Known Secondary structure  TT




GGGSTTGGGG
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   257..260.........270.........280......
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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