Job Description Q22070 Confidence 97.25% Date Sat Apr 13 12:57:32 BST 2013 Rank 376 Aligned Residues 140 % Identity 15% Template c1e8zA_ PDB info PDB header:transferase Chain: A: PDB Molecule:phosphatidylinositol 3-kinase catalytic subunit; PDBTitle: structure determinants of phosphoinositide 3-kinase2 inhibition by wortmannin, ly294002, quercetin, myricetin3 and staurosporine Resolution 2.40 Å

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		1088	.	1090	.	.	.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.	.	.	.	.	.	.	.	.	1130	.	.	.	.	.	.	.	.	.	1140	.	.	.	.	.	.	.	.	.	1150	.	.	.	.	.	.	.	.	.	1160	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		K	P	D	Y	M	L	T	D	D	F	D	P	T	N	T	E	K	F	A	T	A	Y	P	I	R	L	N	V	Q	V	I	G	G	R	H	L	S	R	K	D	K	N	K	G	I	C	S	P	F	V	E	I	E	I	I	G	M	P	C	D	T	K	V	F	Q	T	K	T	I	A	S	N	G	L	N	P	I	W	N	Q
Query Conservation
Alig confidence																																													.	.																													.
Template Conservation																																													.	.																													.
Template Sequence		E	I	H	V	V	L	D	T	P	P	D	P	A	L	D	E	V	R	K	E	E	C	D	R	K	F	R	V	K	I	R	G	I	D	I	P	V	L	P	R	N	T	D	.	.	L	T	V	F	V	E	A	N	I	Q	H	G	Q	Q	V	L	C	Q	R	R	T	S	P	K	P	F	T	E	.	E	V	L	W	N	V
Template Known Secondary structure													G	G	G	G									S												S					S	S		.	.												T	T															S	.
Template Predicted Secondary structure																																													.	.																													.
Template SS confidence
		302	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.			.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.		.	.	.	.	.	.
		1168	.	1170	.	.	.	.	.	.	.	.				.	1180	.	.	.	.	.	.	.	.	.	1190	.	.	.	.	.	.	.	.	.	1200	.	.	.	.	.	.					.	.	.	1210	.	.	.	.	.	.	.	.	.											1220	.	.	.	.	.	.	.	.	.	1230
Predicted Secondary structure													.	.	.																													.	.	.	.														.	.	.	.	.	.	.	.	.	.
Query SS confidence													.	.	.																													.	.	.	.														.	.	.	.	.	.	.	.	.	.
Query Sequence		T	F	T	F	E	I	Q	C	P	E	V	.	.	.	A	L	I	R	F	H	V	E	D	G	D	F	V	G	P	K	T	D	P	F	I	G	Q	A	V	F	P	V	.	.	.	.	D	S	I	R	C	G	F	R	S	V	P	L	K	.	.	.	.	.	.	.	.	.	.	N	Q	Y	S	E	E	L	E	L	S	S
Query Conservation													.	.	.																													.	.	.	.														.	.	.	.	.	.	.	.	.	.
Alig confidence													.	.	.										.	.	.	.	.	.	.	.	.	.										.	.	.	.														.	.	.	.	.	.	.	.	.	.
Template Conservation																									.	.	.	.	.	.	.	.	.	.
Template Sequence		W	L	E	F	S	I	K	I	K	D	L	P	K	G	A	L	L	N	L	Q	I	Y	C	.	.	.	.	.	.	.	.	.	.	L	L	Y	Y	V	N	L	L	L	I	D	H	R	F	L	L	R	R	G	E	Y	V	L	H	M	W	Q	I	S	G	F	N	A	D	K	L	T	S	A	T	N	P	D	K	E	N	S
Template Known Secondary structure									G	G	G			T	T										.	.	.	.	.	.	.	.	.	.									S	B		T	T	S		B										B							G	G	G	G						S		T	T	T	S
Template Predicted Secondary structure																									.	.	.	.	.	.	.	.	.	.
Template SS confidence
		413	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.											.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.
		1231	.	.	.	.	.	.	.	.	1240
Predicted Secondary structure
Query SS confidence
Query Sequence		L	L	V	D	V	Q	M	C	S	R
Query Conservation
Alig confidence
Template Conservation
Template Sequence		M	S	I	S	I	L	L	D	N	H
Template Known Secondary structure
Template Predicted Secondary structure
Template SS confidence
		514	.	.	.	.	.	520	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D