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Job DescriptionQ22070
Confidence100.00%DateSat Apr 13 12:57:32 BST 2013
Rank4Aligned Residues545
% Identity46%Templatec1djyB_
PDB info PDB header:lipid degradationChain: B: PDB Molecule:phosphoinositide-specific phospholipase c, PDBTitle: phosphoinositide-specific phospholipase c-delta1 from rat2 complexed with inositol-2,4,5-trisphosphate
Resolution2.80 Å
Model Dimensions (Å)X:78.713 Y:86.830 Z:61.451

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   210.........220.........230.........240 .........250.........260.........270.........280..
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Query Sequence  DAVARKHMKPFVQTSLQFKVQSDQLQQVTED. . . . . . . QMNSDQFSFASRQLIHVPELFSSRFADLAEKHERKGLVVTFQ
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Template Sequence  NKMNFKELKDFLK. ELNIQVDDGYARKIFRECDHSQTDSLEDEEIETFYKMLTQRAEID. . . . . RAFEEAAGSAETLSVE
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   158.160.........170 .........180.........190.........200.........210..... ....220.........230.
 
   283......290.........300.........310.........320.........330.........340.........350.........360..
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Query Sequence  NFLRFLDGKQFDELASNRTRALEFLNRYFQEDQAYFGDRNEPSMTVFEFCDFLFSRENSLWDPTNEKVTHDMSRPLSHYW
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Template Sequence  RLVTFLQHQQREE. EAGPALALSLIERY. . . . EPSETAKAQRQMTKDGFLMYLLSADGNAFSLAHRRVYQDMDQPLSHYL
Template Known Secondary structure  TS

S.S
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TT
STTTBSB
GGGGS

S
TTS
GGG
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   232.......240.... .....250........ .260.........270.........280.........290.........300......
 
   363......370.........380.........390.........400.........410.........420.........430.........440..
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Query Sequence  IASSHNTYLTGDQLRSESSLDCYAQALLMGCRCIELDCWDGQKKPGSAEFIDIVIYHGYTMTSKILLRDVLHVIRHYAFV
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Template Sequence  VSSSHNTYLLEDQLTGPSSTEAYIRALCKGCRCLELDCWDGPNQ. . . . . . . EPIIYHGYTFTSKILFCDVLRAIRDYAFK
Template Known Secondary structure  SSTTBSS
SSS

B
TT



GGG.......



TTS



TTT
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   307..310.........320.........330.........340.........350 .........360.........370.........
 
   443......450.........460.........470.........480.........490.........500.........510.........520..
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Query Sequence  TSEYPVILSIEDNCSVPAQRLLAQELKDILGDYLLTQPANREEKQLPSPAALKKKIIVKHKKLPIESEDLAAVVKTDEFQ
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Template Sequence  ASPYPVILSLENHCSLEQQRVMARHLRAILGPILLDQPLDGVTTSLPSPEQLKGKILLKGKKLGGLDKL. . . . . . . . . . .
Template Known Secondary structure  S
SS


TTSB

S

SS

SS


TTTTTT







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   380.........390.........400.........410.........420.........430.........440........
 
   523......530.........540.........550.........560.........570.........580.........590.........600..
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Query Sequence  DTEIISRECVKKGILMVKNNNSHEWTSHVFILFPDRLCYLIQTADPENPNDDTVSVSGDEEREEETPSGFGVKPEEMHVT
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   603......610.........620.........630.........640.........650.........660.........670.........680..
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Query Sequence  EEWFHGRCERDEAKKRILEHKEKGNGLFMIRDSNLFIGDFSLSILHDGKVHHVRIRSKIIDKEKKYYFMDNKVCDTLYEL
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   683......690.........700.........710.........720.........730.........740.........750.........760..
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Query Sequence  VSYYTRHYLTTAHFKMVLTIPCPQPQPHLNQPWFSATADKEKAEELLSLVPEDGAFLIRTSSTDSSVYVLSLKVDGEFWH
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   763......770.........780.........790.........800.........810.........820.........830.........840..
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Query Sequence  YRLKRDGRIFVVNQKVFENLNQIVEFYANREFVRGISLRFPVNEKDISHLTAELAEARTPGCYMDLKDLDKEVQARALRP
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   843......850.........860.........870.........880.........890.........900.........910.........920..
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Query Sequence  YRGTADDELSFPANVIITVLRKEEGLWRGRYGSLTGWFPSAHVQEILPEKVSTSETSNYNTIELAGTLIERIHDADRPNV
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   923......930.........940.........950.........960.........970.........980.........990..... ....
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Query Sequence  IRISQSNQHWMNKQYYLLAASSSEEADGWQNNLFELTRSVNTKMSILRTKEKEKRIAAELSNLVVYCQAVPFD. . . PAHI
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . KLVPELSDMIIYCKSVHFGGFSSPGT
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TT

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   487..490.........500.........510..
 
   1000.........1010.........1020. ........1030.........1040.........1050.........1060.........1070......
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Query Sequence  YNDAFYEMCSFVEGKLDKLVEK. . . GLLPFNSRKLSRVYPNGSRITSNNYSPVPMWNAGCHMVALNYQTGDKPMQLNQGK
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Template Sequence  SGQAFYEMASFSESRALRLLQESGNGFVRHNVSCLSRIYPAGWRTDSSNYSPVEMWNGGCQIVALNFQTPGPEMDVYLGC
Template Known Secondary structure 
S

TTS


TT
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TTT


TTS
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   513......520.........530.........540.........550.........560.........570.........580.........590..
 
   1077..1080.........1090...... ...1100.........1110.........1120....... ..1130.........1140.........1150...
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Query Sequence  FLANGRCGYLLKPDYMLTDD. . FDPTNTEKFATAYPIRLNVQVIGGRHLSRKD. KNKGICSPFVEIEIIGMPCDTKVFQT
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Template Sequence  FQDNGGCGYVLKPAFLRDPNTTFNSRALTQGPWWRPERLRVRIISGQQLPKVNKNKNSIVDPKVIVEIHGVGRDTGSRQT
Template Known Secondary structure  TTSGGG
S

GGGS
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TTS

SSTT







S

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SSGGG

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   593......600.........610.........620.........630.........640.........650.........660.........670..
 
   1154.....1160.........1170.........1180.........1190.........1200.........1210.........1220.........1230...
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Query Sequence  KTIASNGLNPIWNQTFTFEIQCPEVALIRFHVEDGDFVGPKTDPFIGQAVFPVDSIRCGFRSVPLKNQYSEELELSSLLV
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Template Sequence  AVITNNGFNPRWDMEFEFEVTVPDLALVRFMVEDYDSSS. . KNDFIGQSTIPWNSLKQGYRHVHLLSKNGDQHPSATLFV
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TT
SSS
S
GGG


TTS..

GGGB


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   673......680.........690.........700.........710. ........720.........730.........740.........750
 
   1234.....
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Query Sequence  DVQMCS
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Template Sequence  KISIQD
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   751.....
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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