Job Description Q22070 Confidence 99.89% Date Sat Apr 13 12:57:32 BST 2013 Rank 18 Aligned Residues 197 % Identity 26% Template c1a81E_ PDB info PDB header:complex (transferase/peptide) Chain: E: PDB Molecule:syk kinase; PDBTitle: crystal structure of the tandem sh2 domain of the syk kinase bound to2 a dually tyrosine-phosphorylated itam Resolution 3.00 Å Model Dimensions (Å) X: Y: Z:

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		605	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		W	F	H	G	R	C	E	R	D	E	A	K	K	R	I	L	E	H	K	E	K	G	N	G	L	F	M	I	R	D	S	N	L	F	I	G	D	F	S	L	S	I	L	H	D	G	K	V	H	H	V	R	I	R	S	K	I	I	D	K	E	K	K	Y	Y	F	M	D	N	K	V	C	D	T	L	Y	E	L	V	S
Query Conservation
Alig confidence																					.																																								.	.	.
Template Conservation																					.																																								.	.	.
Template Sequence		F	F	F	G	N	I	T	R	E	E	A	E	D	Y	L	V	Q	G	G	.	M	S	D	G	L	Y	L	L	R	Q	S	R	N	Y	L	G	G	F	A	L	S	V	A	H	G	R	K	A	H	H	Y	T	I	E	R	E	L	N	G	.	.	.	T	Y	A	I	A	G	G	R	T	H	A	S	P	A	D	L	C	H
Template Known Secondary structure		T			S	S												T	T	T	.			T	T								S	S	S	T	T									S	S	S										T	T	T	.	.	.					T	T	S			B	S	S
Template Predicted Secondary structure																					.																																								.	.	.
Template SS confidence
		15	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.		.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.				.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90
		685	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.														.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730		.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750
Predicted Secondary structure																							.	.	.	.	.	.	.	.	.	.	.	.	.																										.
Query SS confidence																							.	.	.	.	.	.	.	.	.	.	.	.	.																										.
Query Sequence		Y	Y	T	R	H	Y	L	T	T	A	H	F	K	M	V	L	T	I	P	C	P	.	.	.	.	.	.	.	.	.	.	.	.	.	Q	P	Q	P	H	L	N	Q	P	W	F	S	A	T	A	D	K	E	K	A	E	E	L	L	S	.	L	V	P	E	D	G	A	F	L	I	R	T	S	S	T	D	S	S	V	Y
Query Conservation																							.	.	.	.	.	.	.	.	.	.	.	.	.																										.
Alig confidence																							.	.	.	.	.	.	.	.	.	.	.	.	.																										.														.
Template Conservation																																																																											.
Template Sequence		Y	H	S	Q	E	S	D	G	L	V	C	L	L	K	K	P	F	N	R	P	Q	G	V	Q	P	K	T	P	Q	L	E	K	L	I	A	T	T	A	H	E	K	M	P	W	F	H	G	K	I	S	R	E	E	S	E	Q	I	V	L	I	G	S	K	T	N	G	K	F	L	I	R	A	R	.	D	N	N	G	S	Y
Template Known Secondary structure				T	T			T	T	S	S	S				S	B					T	T															T	S	G	G	G		T	T																S	S				T	T								.	S	S	S	S
Template Predicted Secondary structure																																																																											.
Template SS confidence
		91	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.		.	.	.	.	.	.
		751	.	.	.	.	.	.	.	.	760	.	.	.	.	.			.	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.
Predicted Secondary structure																	.	.
Query SS confidence																	.	.
Query Sequence		V	L	S	L	K	V	D	G	E	F	W	H	Y	R	L	.	.	K	R	D	G	R	I	F	V	V	N	Q	K	V	F	E	N	L	N	Q	I	V	E	F	Y	A	N	R	E	F	V	R	G	I	S	L	R	F	P	V	N	E
Query Conservation																	.	.
Alig confidence																	.	.
Template Conservation
Template Sequence		A	L	C	L	L	H	E	G	K	V	L	H	Y	R	I	D	K	D	K	T	G	K	L	S	I	P	E	G	K	K	F	D	T	L	W	Q	L	V	E	H	Y	S	Y	K	A	D	G	L	L	R	V	L	T	V	P	C	Q	K
Template Known Secondary structure								T	T											T	T	S					T	T	S			B	S										T	T			T	T	S	S	S				S	B
Template Predicted Secondary structure
Template SS confidence
		204	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D