Phyre 2 Results for Q22070

Phyre Home | Retrieve Phyre Job Id

Email | l.a.kelley@imperial.ac.uk
Description | Q22070
Date | Sat Apr 13 12:57:32 BST 2013
Unique Job ID | 810548c15e619017

Summary |

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å): | X:61.646 Y:94.080 Z:99.817
| Close Jmol

Model (left) based on template c3ohmB_
Top template information
PDB header:signaling protein / hydrolase Chain: B: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase PDBTitle: crystal structure of activated g alpha q bound to its effector2 phospholipase c beta 3
Confidence and coverage
Confidence: | 100.0% | Coverage: | 52%
708 residues ( 52% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
3D viewing
Interactive 3D view in Jmol

Sequence analysis |

Secondary structure and disorder prediction |

|  | 1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60
Sequence |  | M | Q | H | G | S | L | G | P | S | S | S | S | R | K | T | T | V | T | S | T | A | G | S | V | H | L | H | H | R | S | S | N | G | F | S | T | A | S | R | A | Q | L | N | R | H | N | E | M | D | F | G | K | M | F | A | A | M | E | K | G
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120
Sequence |  | H | K | V | C | K | I | A | V | L | K | K | W | D | P | A | Y | K | Q | L | T | L | D | R | Y | S | R | Q | I | F | L | T | K | L | E | L | S | A | V | R | N | K | P | T | I | L | D | I | R | Q | I | R | E | V | Q | T | L | N | Y | K | L
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  | ? | ? | ? | ? |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180
Sequence |  | N | T | I | K | V | D | D | K | W | K | K | D | R | E | I | V | N | F | D | S | K | A | I | L | I | I | S | Y | G | M | G | F | A | L | S | Y | W | I | L | L | F | E | S | E | D | A | C | K | L | W | S | Q | G | L | H | N | L | M | M | D
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240
Sequence |  | T | R | D | R | D | S | S | P | H | P | L | R | I | E | R | F | L | H | K | H | F | L | S | L | M | S | P | A | N | D | A | V | A | R | K | H | M | K | P | F | V | Q | T | S | L | Q | F | K | V | Q | S | D | Q | L | Q | Q | V | T | E | D
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300
Sequence |  | Q | M | N | S | D | Q | F | S | F | A | S | R | Q | L | I | H | V | P | E | L | F | S | S | R | F | A | D | L | A | E | K | H | E | R | K | G | L | V | V | T | F | Q | N | F | L | R | F | L | D | G | K | Q | F | D | E | L | A | S | N | R
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360
Sequence |  | T | R | A | L | E | F | L | N | R | Y | F | Q | E | D | Q | A | Y | F | G | D | R | N | E | P | S | M | T | V | F | E | F | C | D | F | L | F | S | R | E | N | S | L | W | D | P | T | N | E | K | V | T | H | D | M | S | R | P | L | S | H
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420
Sequence |  | Y | W | I | A | S | S | H | N | T | Y | L | T | G | D | Q | L | R | S | E | S | S | L | D | C | Y | A | Q | A | L | L | M | G | C | R | C | I | E | L | D | C | W | D | G | Q | K | K | P | G | S | A | E | F | I | D | I | V | I | Y | H | G
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480
Sequence |  | Y | T | M | T | S | K | I | L | L | R | D | V | L | H | V | I | R | H | Y | A | F | V | T | S | E | Y | P | V | I | L | S | I | E | D | N | C | S | V | P | A | Q | R | L | L | A | Q | E | L | K | D | I | L | G | D | Y | L | L | T | Q | P
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540
Sequence |  | A | N | R | E | E | K | Q | L | P | S | P | A | A | L | K | K | K | I | I | V | K | H | K | K | L | P | I | E | S | E | D | L | A | A | V | V | K | T | D | E | F | Q | D | T | E | I | I | S | R | E | C | V | K | K | G | I | L | M | V | K
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600
Sequence |  | N | N | N | S | H | E | W | T | S | H | V | F | I | L | F | P | D | R | L | C | Y | L | I | Q | T | A | D | P | E | N | P | N | D | D | T | V | S | V | S | G | D | E | E | R | E | E | E | T | P | S | G | F | G | V | K | P | E | E | M | H
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  | ? |  |  |  |  |  |  |  |  |  |  |  | ? |  | ? | ? | ? | ? | ? | ? | ? |  | ? | ? | ? | ? | ? | ? |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  | ? |  |  | ? |  |  | ? | ? |  | ? |  | ? | ? | ? |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660
Sequence |  | V | T | E | E | W | F | H | G | R | C | E | R | D | E | A | K | K | R | I | L | E | H | K | E | K | G | N | G | L | F | M | I | R | D | S | N | L | F | I | G | D | F | S | L | S | I | L | H | D | G | K | V | H | H | V | R | I | R | S | K
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  | ? |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . | . | . | 710 | . | . | . | . | . | . | . | . | . | 720
Sequence |  | I | I | D | K | E | K | K | Y | Y | F | M | D | N | K | V | C | D | T | L | Y | E | L | V | S | Y | Y | T | R | H | Y | L | T | T | A | H | F | K | M | V | L | T | I | P | C | P | Q | P | Q | P | H | L | N | Q | P | W | F | S | A | T | A
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? |  | ? |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 730 | . | . | . | . | . | . | . | . | . | 740 | . | . | . | . | . | . | . | . | . | 750 | . | . | . | . | . | . | . | . | . | 760 | . | . | . | . | . | . | . | . | . | 770 | . | . | . | . | . | . | . | . | . | 780
Sequence |  | D | K | E | K | A | E | E | L | L | S | L | V | P | E | D | G | A | F | L | I | R | T | S | S | T | D | S | S | V | Y | V | L | S | L | K | V | D | G | E | F | W | H | Y | R | L | K | R | D | G | R | I | F | V | V | N | Q | K | V | F | E
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  | ? | ? |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 790 | . | . | . | . | . | . | . | . | . | 800 | . | . | . | . | . | . | . | . | . | 810 | . | . | . | . | . | . | . | . | . | 820 | . | . | . | . | . | . | . | . | . | 830 | . | . | . | . | . | . | . | . | . | 840
Sequence |  | N | L | N | Q | I | V | E | F | Y | A | N | R | E | F | V | R | G | I | S | L | R | F | P | V | N | E | K | D | I | S | H | L | T | A | E | L | A | E | A | R | T | P | G | C | Y | M | D | L | K | D | L | D | K | E | V | Q | A | R | A | L
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 850 | . | . | . | . | . | . | . | . | . | 860 | . | . | . | . | . | . | . | . | . | 870 | . | . | . | . | . | . | . | . | . | 880 | . | . | . | . | . | . | . | . | . | 890 | . | . | . | . | . | . | . | . | . | 900
Sequence |  | R | P | Y | R | G | T | A | D | D | E | L | S | F | P | A | N | V | I | I | T | V | L | R | K | E | E | G | L | W | R | G | R | Y | G | S | L | T | G | W | F | P | S | A | H | V | Q | E | I | L | P | E | K | V | S | T | S | E | T | S | N
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 910 | . | . | . | . | . | . | . | . | . | 920 | . | . | . | . | . | . | . | . | . | 930 | . | . | . | . | . | . | . | . | . | 940 | . | . | . | . | . | . | . | . | . | 950 | . | . | . | . | . | . | . | . | . | 960
Sequence |  | Y | N | T | I | E | L | A | G | T | L | I | E | R | I | H | D | A | D | R | P | N | V | I | R | I | S | Q | S | N | Q | H | W | M | N | K | Q | Y | Y | L | L | A | A | S | S | S | E | E | A | D | G | W | Q | N | N | L | F | E | L | T | R
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? |  | ? |  |  |  | ? | ? |  |  | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? |  | ? | ? |  |  | ? |  | ? | ? |  | ? |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 970 | . | . | . | . | . | . | . | . | . | 980 | . | . | . | . | . | . | . | . | . | 990 | . | . | . | . | . | . | . | . | . | 1000 | . | . | . | . | . | . | . | . | . | 1010 | . | . | . | . | . | . | . | . | . | 1020
Sequence |  | S | V | N | T | K | M | S | I | L | R | T | K | E | K | E | K | R | I | A | A | E | L | S | N | L | V | V | Y | C | Q | A | V | P | F | D | P | A | H | I | Y | N | D | A | F | Y | E | M | C | S | F | V | E | G | K | L | D | K | L | V | E
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  | ? |  | ? | ? |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 1030 | . | . | . | . | . | . | . | . | . | 1040 | . | . | . | . | . | . | . | . | . | 1050 | . | . | . | . | . | . | . | . | . | 1060 | . | . | . | . | . | . | . | . | . | 1070 | . | . | . | . | . | . | . | . | . | 1080
Sequence |  | K | G | L | L | P | F | N | S | R | K | L | S | R | V | Y | P | N | G | S | R | I | T | S | N | N | Y | S | P | V | P | M | W | N | A | G | C | H | M | V | A | L | N | Y | Q | T | G | D | K | P | M | Q | L | N | Q | G | K | F | L | A | N
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 1090 | . | . | . | . | . | . | . | . | . | 1100 | . | . | . | . | . | . | . | . | . | 1110 | . | . | . | . | . | . | . | . | . | 1120 | . | . | . | . | . | . | . | . | . | 1130 | . | . | . | . | . | . | . | . | . | 1140
Sequence |  | G | R | C | G | Y | L | L | K | P | D | Y | M | L | T | D | D | F | D | P | T | N | T | E | K | F | A | T | A | Y | P | I | R | L | N | V | Q | V | I | G | G | R | H | L | S | R | K | D | K | N | K | G | I | C | S | P | F | V | E | I | E
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? |  | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 1150 | . | . | . | . | . | . | . | . | . | 1160 | . | . | . | . | . | . | . | . | . | 1170 | . | . | . | . | . | . | . | . | . | 1180 | . | . | . | . | . | . | . | . | . | 1190 | . | . | . | . | . | . | . | . | . | 1200
Sequence |  | I | I | G | M | P | C | D | T | K | V | F | Q | T | K | T | I | A | S | N | G | L | N | P | I | W | N | Q | T | F | T | F | E | I | Q | C | P | E | V | A | L | I | R | F | H | V | E | D | G | D | F | V | G | P | K | T | D | P | F | I | G
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 1210 | . | . | . | . | . | . | . | . | . | 1220 | . | . | . | . | . | . | . | . | . | 1230 | . | . | . | . | . | . | . | . | . | 1240 | . | . | . | . | . | . | . | . | . | 1250 | . | . | . | . | . | . | . | . | . | 1260
Sequence |  | Q | A | V | F | P | V | D | S | I | R | C | G | F | R | S | V | P | L | K | N | Q | Y | S | E | E | L | E | L | S | S | L | L | V | D | V | Q | M | C | S | R | E | G | T | Q | L | I | R | S | S | S | H | F | L | Q | A | S | R | L | A | P
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 1270 | . | . | . | . | . | . | . | . | . | 1280 | . | . | . | . | . | . | . | . | . | 1290 | . | . | . | . | . | . | . | . | . | 1300 | . | . | . | . | . | . | . | . | . | 1310 | . | . | . | . | . | . | . | . | . | 1320
Sequence |  | V | F | A | H | R | K | I | T | N | G | D | S | I | P | R | E | M | A | P | R | L | R | T | S | A | T | D | R | S | L | D | S | P | T | N | S | E | S | R | A | T | L | L | S | G | Q | R | G | S | Q | D | S | M | D | S | A | A | E | T | S
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 1330 | . | . | . | . | . | . | . | . | . | 1340 | . | . | . | . | . | . | . | . | . | 1350
Sequence |  | S | I | A | S | G | T | I | S | S | R | D | G | K | K | K | Q | N | W | L | K | K | F | S | F | G | K | S | S | K | S
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |

Confidence Key
High(9) |  |  |  |  |  |  |  |  |  |  | Low (0)
? | Disordered ( 32%)
| Alpha helix ( 26%)
| Beta strand ( 18%)

Domain analysis |

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank | Aligned region
--- | ---
1 |
| c3ohmB_ |

### PDB 3ohm chain B

Region: 52 - 1265
Aligned: 708
Modelled: 744
Confidence: 100.0%
Identity: 37%
PDB header:signaling protein / hydrolase
Chain: B: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase
PDBTitle: crystal structure of activated g alpha q bound to its effector2 phospholipase c beta 3

Phyre2
2 |
| c3qr0A_ |

### PDB 3qr0 chain A

Region: 52 - 1273
Aligned: 732
Modelled: 771
Confidence: 100.0%
Identity: 33%
PDB header:hydrolase
Chain: A: PDB Molecule:phospholipase c-beta (plc-beta);
PDBTitle: crystal structure of s. officinalis plc21

Phyre2
3 |
| c2fjuB_ |

### PDB 2fju chain B

Region: 52 - 1239
Aligned: 661
Modelled: 720
Confidence: 100.0%
Identity: 37%
PDB header:signaling protein,apoptosis/hydrolase
Chain: B: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate
PDBTitle: activated rac1 bound to its effector phospholipase c beta 2

Phyre2
4 |
| c1djyB_ |

### PDB 1djy chain B

Region: 210 - 1239
Aligned: 545
Modelled: 565
Confidence: 100.0%
Identity: 46%
PDB header:lipid degradation
Chain: B: PDB Molecule:phosphoinositide-specific phospholipase c,
PDBTitle: phosphoinositide-specific phospholipase c-delta1 from rat2 complexed with inositol-2,4,5-trisphosphate

Phyre2
5 |
| d2zkmx4 |

### PDB 2zkm chain X domain 4

Region: 352 - 1095
Aligned: 287
Modelled: 294
Confidence: 100.0%
Identity: 54%
Fold: TIM beta/alpha-barrel
Superfamily: PLC-like phosphodiesterases
Family: Mammalian PLC

Phyre2
6 |
| d1qasa3 |

### PDB 1qas chain A domain 3

Region: 355 - 1099
Aligned: 269
Modelled: 276
Confidence: 100.0%
Identity: 59%
Fold: TIM beta/alpha-barrel
Superfamily: PLC-like phosphodiesterases
Family: Mammalian PLC

Phyre2
7 |
| c3gqiB_ |

### PDB 3gqi chain B

Region: 600 - 818
Aligned: 218
Modelled: 219
Confidence: 100.0%
Identity: 32%
PDB header:transferase/transferase inhibitor
Chain: B: PDB Molecule:phospholipase c-gamma-1;
PDBTitle: crystal structure of activated receptor tyrosine kinase in complex2 with substrates

Phyre2
8 |
| c2b3oA_ |

### PDB 2b3o chain A

Region: 604 - 847
Aligned: 237
Modelled: 238
Confidence: 100.0%
Identity: 24%
PDB header:hydrolase
Chain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type
PDBTitle: crystal structure of human tyrosine phosphatase shp-1

Phyre2
9 |
| c3ps5A_ |

### PDB 3ps5 chain A

Region: 604 - 809
Aligned: 199
Modelled: 204
Confidence: 100.0%
Identity: 29%
PDB header:hydrolase, signaling protein
Chain: A: PDB Molecule:tyrosine-protein phosphatase non-receptor type 6;
PDBTitle: crystal structure of the full-length human protein tyrosine2 phosphatase shp-1

Phyre2
10 |
| d2zkmx2 |

### PDB 2zkm chain X domain 2

Region: 1112 - 1239
Aligned: 117
Modelled: 128
Confidence: 100.0%
Identity: 27%
Fold: C2 domain-like
Superfamily: C2 domain (Calcium/lipid-binding domain, CaLB)
Family: PLC-like (P variant)

Phyre2
11 |
| c2shpA_ |

### PDB 2shp chain A

Region: 602 - 807
Aligned: 199
Modelled: 204
Confidence: 100.0%
Identity: 29%
PDB header:tyrosine phosphatase
Chain: A: PDB Molecule:shp-2;
PDBTitle: tyrosine phosphatase shp-2

Phyre2
12 |
| d1qasa2 |

### PDB 1qas chain A domain 2

Region: 1110 - 1239
Aligned: 124
Modelled: 130
Confidence: 100.0%
Identity: 38%
Fold: C2 domain-like
Superfamily: C2 domain (Calcium/lipid-binding domain, CaLB)
Family: PLC-like (P variant)

Phyre2
13 |
| c2lqnA_ |

### PDB 2lqn chain A

Region: 598 - 897
Aligned: 290
Modelled: 300
Confidence: 99.9%
Identity: 20%
PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of crkl

Phyre2
14 |
| c4fl2A_ |

### PDB 4fl2 chain A

Region: 605 - 843
Aligned: 231
Modelled: 239
Confidence: 99.9%
Identity: 27%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase syk;
PDBTitle: structural and biophysical characterization of the syk activation2 switch

Phyre2
15 |
| c2oq1A_ |

### PDB 2oq1 chain A

Region: 605 - 805
Aligned: 193
Modelled: 201
Confidence: 99.9%
Identity: 30%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: tandem sh2 domains of zap-70 with 19-mer zeta1 peptide

Phyre2
16 |
| c2eyzA_ |

### PDB 2eyz chain A

Region: 598 - 896
Aligned: 277
Modelled: 284
Confidence: 99.9%
Identity: 17%
PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform ii

Phyre2
17 |
| c2ozoA_ |

### PDB 2ozo chain A

Region: 595 - 805
Aligned: 201
Modelled: 211
Confidence: 99.9%
Identity: 28%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: autoinhibited intact human zap-70

Phyre2
18 |
| c1a81E_ |

### PDB 1a81 chain E

Region: 605 - 806
Aligned: 197
Modelled: 202
Confidence: 99.9%
Identity: 26%
PDB header:complex (transferase/peptide)
Chain: E: PDB Molecule:syk kinase;
PDBTitle: crystal structure of the tandem sh2 domain of the syk kinase bound to2 a dually tyrosine-phosphorylated itam

Phyre2
19 |
| d2zkmx1 |

### PDB 2zkm chain X domain 1

Region: 193 - 351
Aligned: 127
Modelled: 158
Confidence: 99.8%
Identity: 17%
Fold: EF Hand-like
Superfamily: EF-hand
Family: EF-hand modules in multidomain proteins

Phyre2
20 |
| d1qasa1 |

### PDB 1qas chain A domain 1

Region: 251 - 354
Aligned: 94
Modelled: 104
Confidence: 99.8%
Identity: 20%
Fold: EF Hand-like
Superfamily: EF-hand
Family: EF-hand modules in multidomain proteins

Phyre2
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Detailed template information |

# | Template | Alignment Coverage | 3D Model | Confidence | % i.d. | Template Information
--- | --- | --- | --- | --- | --- | ---
1 | c3ohmB_ |
|  | 100.0 | 37 | PDB header:signaling protein / hydrolase Chain: B: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase PDBTitle: crystal structure of activated g alpha q bound to its effector2 phospholipase c beta 3
2 | c3qr0A_ |
|  | 100.0 | 33 | PDB header:hydrolase Chain: A: PDB Molecule:phospholipase c-beta (plc-beta); PDBTitle: crystal structure of s. officinalis plc21
3 | c2fjuB_ |
|  | 100.0 | 37 | PDB header:signaling protein,apoptosis/hydrolase Chain: B: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate PDBTitle: activated rac1 bound to its effector phospholipase c beta 2
4 | c1djyB_ |
|  | 100.0 | 46 | PDB header:lipid degradation Chain: B: PDB Molecule:phosphoinositide-specific phospholipase c, PDBTitle: phosphoinositide-specific phospholipase c-delta1 from rat2 complexed with inositol-2,4,5-trisphosphate
5 | d2zkmx4 |
|  | 100.0 | 54 | Fold:TIM beta/alpha-barrel Superfamily:PLC-like phosphodiesterases Family:Mammalian PLC
6 | d1qasa3 |
|  | 100.0 | 59 | Fold:TIM beta/alpha-barrel Superfamily:PLC-like phosphodiesterases Family:Mammalian PLC
7 | c3gqiB_ |
|  | 100.0 | 32 | PDB header:transferase/transferase inhibitor Chain: B: PDB Molecule:phospholipase c-gamma-1; PDBTitle: crystal structure of activated receptor tyrosine kinase in complex2 with substrates
8 | c2b3oA_ |
|  | 100.0 | 24 | PDB header:hydrolase Chain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type PDBTitle: crystal structure of human tyrosine phosphatase shp-1
9 | c3ps5A_ |
|  | 100.0 | 29 | PDB header:hydrolase, signaling protein Chain: A: PDB Molecule:tyrosine-protein phosphatase non-receptor type 6; PDBTitle: crystal structure of the full-length human protein tyrosine2 phosphatase shp-1
10 | d2zkmx2 |
|  | 100.0 | 27 | Fold:C2 domain-like Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB) Family:PLC-like (P variant)
11 | c2shpA_ |
|  | 100.0 | 29 | PDB header:tyrosine phosphatase Chain: A: PDB Molecule:shp-2; PDBTitle: tyrosine phosphatase shp-2
12 | d1qasa2 |
|  | 100.0 | 38 | Fold:C2 domain-like Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB) Family:PLC-like (P variant)
13 | c2lqnA_ |
|  | 99.9 | 20 | PDB header:signaling protein Chain: A: PDB Molecule:crk-like protein; PDBTitle: solution structure of crkl
14 | c4fl2A_ |
|  | 99.9 | 27 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase syk; PDBTitle: structural and biophysical characterization of the syk activation2 switch
15 | c2oq1A_ |
|  | 99.9 | 30 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase zap-70; PDBTitle: tandem sh2 domains of zap-70 with 19-mer zeta1 peptide
16 | c2eyzA_ |
|  | 99.9 | 17 | PDB header:signaling protein Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog PDBTitle: ct10-regulated kinase isoform ii
17 | c2ozoA_ |
|  | 99.9 | 28 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase zap-70; PDBTitle: autoinhibited intact human zap-70
18 | c1a81E_ |
|  | 99.9 | 26 | PDB header:complex (transferase/peptide) Chain: E: PDB Molecule:syk kinase; PDBTitle: crystal structure of the tandem sh2 domain of the syk kinase bound to2 a dually tyrosine-phosphorylated itam
19 | d2zkmx1 |
|  | 99.8 | 17 | Fold:EF Hand-like Superfamily:EF-hand Family:EF-hand modules in multidomain proteins
20 | d1qasa1 |
|  | 99.8 | 20 | Fold:EF Hand-like Superfamily:EF-hand Family:EF-hand modules in multidomain proteins
21 | d2zkmx3 |
| not modelled | 99.8 | 18 | Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain)
22 | c2eyyA_ |
| not modelled | 99.8 | 23 | PDB header:signaling protein Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog PDBTitle: ct10-regulated kinase isoform i
23 | d1djxb1 |
| not modelled | 99.8 | 19 | Fold:EF Hand-like Superfamily:EF-hand Family:EF-hand modules in multidomain proteins
24 | c3h4wA_ |
| not modelled | 99.8 | 23 | PDB header:hydrolase Chain: A: PDB Molecule:phosphatidylinositol-specific phospholipase c1; PDBTitle: structure of a ca+2 dependent phosphatidylinositol-specific2 phospholipase c (pi-plc) enzyme from streptomyces antibioticus
25 | c2dvjA_ |
| not modelled | 99.7 | 24 | PDB header:signaling protein Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog, PDBTitle: phosphorylated crk-ii
26 | c3qwxX_ |
| not modelled | 99.7 | 22 | PDB header:signaling protein Chain: X: PDB Molecule:cell death abnormality protein 2; PDBTitle: ced-2 1-174
27 | c3or8A_ |
| not modelled | 99.6 | 12 | PDB header:transcription Chain: A: PDB Molecule:transcription elongation factor spt6; PDBTitle: a tandem sh2 domain in transcription elongation factor spt6
28 | c3qwyA_ |
| not modelled | 99.6 | 22 | PDB header:signaling protein Chain: A: PDB Molecule:cell death abnormality protein 2; PDBTitle: ced-2
29 | c2fjlA_ |
| not modelled | 99.6 | 32 | PDB header:hydrolase Chain: A: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate PDBTitle: solution structure of the split ph domain in phospholipase2 c-gamma1
30 | c2xp1A_ |
| not modelled | 99.6 | 20 | PDB header:transcription Chain: A: PDB Molecule:spt6; PDBTitle: structure of the tandem sh2 domains from antonospora locustae2 transcription elongation factor spt6
31 | d1maia_ |
| not modelled | 99.6 | 17 | Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain)
32 | c2eobA_ |
| not modelled | 99.6 | 33 | PDB header:hydrolase Chain: A: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate PDBTitle: solution structure of the second sh2 domain from rat plc2 gamma-2
33 | d2nq3a1 |
| not modelled | 99.5 | 21 | Fold:C2 domain-like Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB) Family:PLC-like (P variant)
34 | c2nq3A_ |
| not modelled | 99.5 | 21 | PDB header:ligase Chain: A: PDB Molecule:itchy homolog e3 ubiquitin protein ligase; PDBTitle: crystal structure of the c2 domain of human itchy homolog2 e3 ubiquitin protein ligase
35 | c3m7fB_ |
| not modelled | 99.5 | 23 | PDB header:signaling protein/ligase Chain: B: PDB Molecule:e3 ubiquitin-protein ligase nedd4; PDBTitle: crystal structure of the nedd4 c2/grb10 sh2 complex
36 | d2r83a1 |
| not modelled | 99.5 | 27 | Fold:C2 domain-like Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB) Family:Synaptotagmin-like (S variant)
37 | d1gmia_ |
| not modelled | 99.5 | 17 | Fold:C2 domain-like Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB) Family:PLC-like (P variant)
38 | c2chdA_ |
| not modelled | 99.5 | 27 | PDB header:protein transport Chain: A: PDB Molecule:rabphilin-3a; PDBTitle: crystal structure of the c2a domain of rabphilin-3a
39 | c3nsjA_ |
| not modelled | 99.5 | 20 | PDB header:immune system Chain: A: PDB Molecule:perforin-1; PDBTitle: the x-ray crystal structure of lymphocyte perforin
40 | c2q3xA_ |
| not modelled | 99.5 | 19 | PDB header:transport protein Chain: A: PDB Molecule:regulating synaptic membrane exocytosis protein 1; PDBTitle: the rim1alpha c2b domain
41 | c3l9bA_ |
| not modelled | 99.5 | 17 | PDB header:membrane protein Chain: A: PDB Molecule:otoferlin; PDBTitle: crystal structure of rat otoferlin c2a
42 | d1rlwa_ |
| not modelled | 99.5 | 24 | Fold:C2 domain-like Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB) Family:PLC-like (P variant)
43 | d1ugka_ |
| not modelled | 99.4 | 21 | Fold:C2 domain-like Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB) Family:Synaptotagmin-like (S variant)
44 | c2dmhA_ |
| not modelled | 99.4 | 19 | PDB header:lipid binding protein Chain: A: PDB Molecule:myoferlin; PDBTitle: solution structure of the first c2 domain of human myoferlin
45 | c2gsbA_ |
| not modelled | 99.4 | 23 | PDB header:signaling protein Chain: A: PDB Molecule:ras gtpase-activating protein 1; PDBTitle: solution structure of the second sh2 domain of human ras2 gtpase-activating protein 1
46 | c2hdxB_ |
| not modelled | 99.4 | 22 | PDB header:signaling protein Chain: B: PDB Molecule:sh2-b ph domain containing signaling mediator 1 PDBTitle: crystal structure of the src homology-2 domain of sh2-b in2 complex with jak2 ptyr813 phosphopeptide
47 | d1dsya_ |
| not modelled | 99.4 | 30 | Fold:C2 domain-like Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB) Family:Synaptotagmin-like (S variant)
48 | c2vszA_ |
| not modelled | 99.4 | 17 | PDB header:apoptosis Chain: A: PDB Molecule:engulfment and cell motility protein 1; PDBTitle: crystal structure of the elmo1 ph domain
49 | c3fbkB_ |
| not modelled | 99.4 | 22 | PDB header:signaling protein Chain: B: PDB Molecule:regulator of g-protein signaling 3; PDBTitle: crystal structure of the c2 domain of the human regulator2 of g-protein signaling 3 isoform 6 (rgp3), northeast3 structural genomics consortium target hr5550a
50 | d1v27a_ |
| not modelled | 99.4 | 24 | Fold:C2 domain-like Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB) Family:Synaptotagmin-like (S variant)
51 | c3kwtA_ |
| not modelled | 99.4 | 26 | PDB header:metal binding protein Chain: A: PDB Molecule:munc13-1; PDBTitle: munc13-1 c2b-domain, calcium-free
52 | c2fk9A_ |
| not modelled | 99.4 | 18 | PDB header:transferase Chain: A: PDB Molecule:protein kinase c, eta type; PDBTitle: human protein kinase c, eta
53 | c3hizB_ |
| not modelled | 99.4 | 26 | PDB header:transferase/oncoprotein Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit PDBTitle: crystal structure of p110alpha h1047r mutant in complex with2 nish2 of p85alpha
54 | c2z0uB_ |
| not modelled | 99.4 | 13 | PDB header:lipid binding protein Chain: B: PDB Molecule:ww domain-containing protein 1; PDBTitle: crystal structure of c2 domain of kibra protein
55 | c2dx0B_ |
| not modelled | 99.3 | 36 | PDB header:hydrolase Chain: B: PDB Molecule:phospholipase c, gamma 2; PDBTitle: crystal structure of the n-terminal sh2 domain of mouse2 phospholipase c-gamma 2
56 | c2jqzA_ |
| not modelled | 99.3 | 21 | PDB header:ligase Chain: A: PDB Molecule:e3 ubiquitin-protein ligase smurf2; PDBTitle: solution structure of the c2 domain of human smurf2
57 | d2fcia1 |
| not modelled | 99.3 | 30 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
58 | d1bdya_ |
| not modelled | 99.3 | 16 | Fold:C2 domain-like Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB) Family:PLC-like (P variant)
59 | d2izva2 |
| not modelled | 99.3 | 19 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
60 | c3jzyA_ |
| not modelled | 99.3 | 30 | PDB header:endocytosis Chain: A: PDB Molecule:intersectin 2; PDBTitle: crystal structure of human intersectin 2 c2 domain
61 | d1a25a_ |
| not modelled | 99.3 | 26 | Fold:C2 domain-like Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB) Family:Synaptotagmin-like (S variant)
62 | d3c7ia1 |
| not modelled | 99.3 | 27 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
63 | c2crhA_ |
| not modelled | 99.3 | 23 | PDB header:signaling protein Chain: A: PDB Molecule:vav proto-oncogene; PDBTitle: solution structure of the sh2 domain of human proto-2 oncogene protein vav1
64 | c1dqvA_ |
| not modelled | 99.3 | 30 | PDB header:endocytosis/exocytosis Chain: A: PDB Molecule:synaptotagmin iii; PDBTitle: crystal structure of synaptotagmin iii c2a/c2b
65 | c2d8kA_ |
| not modelled | 99.3 | 28 | PDB header:endocytosis/exocytosis Chain: A: PDB Molecule:synaptotagmin vii; PDBTitle: solution structure of the first c2 domain of synaptotagmin2 vii
66 | d1wfma_ |
| not modelled | 99.3 | 16 | Fold:C2 domain-like Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB) Family:Synaptotagmin-like (S variant)
67 | c2enpA_ |
| not modelled | 99.3 | 26 | PDB header:transport protein Chain: A: PDB Molecule:b/k protein; PDBTitle: solution structure of the first c2 domain from human b/k2 protein
68 | d1rsya_ |
| not modelled | 99.3 | 27 | Fold:C2 domain-like Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB) Family:Synaptotagmin-like (S variant)
69 | c2y3aB_ |
| not modelled | 99.3 | 30 | PDB header:transferase Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit beta; PDBTitle: crystal structure of p110beta in complex with icsh2 of p85beta and2 the drug gdc-0941
70 | c2eo6A_ |
| not modelled | 99.2 | 27 | PDB header:signaling protein Chain: A: PDB Molecule:b-cell linker protein; PDBTitle: solution structure of the sh2 domain from mouse b-cell2 linker protein blnk
71 | d2bwqa1 |
| not modelled | 99.2 | 23 | Fold:C2 domain-like Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB) Family:Synaptotagmin-like (S variant)
72 | c2dlzA_ |
| not modelled | 99.2 | 27 | PDB header:signaling protein Chain: A: PDB Molecule:protein vav-2; PDBTitle: solution structure of the sh2 domain of human protein vav-2
73 | d1a81e2 |
| not modelled | 99.2 | 37 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
74 | d2oq1a2 |
| not modelled | 99.2 | 27 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
75 | d2ep6a1 |
| not modelled | 99.2 | 30 | Fold:C2 domain-like Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB) Family:PLC-like (P variant)
76 | d2qmsa1 |
| not modelled | 99.2 | 27 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
77 | d2cjta1 |
| not modelled | 99.2 | 24 | Fold:C2 domain-like Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB) Family:PLC-like (P variant)
78 | c2nsqA_ |
| not modelled | 99.2 | 22 | PDB header:ligase Chain: A: PDB Molecule:e3 ubiquitin-protein ligase nedd4-like protein; PDBTitle: crystal structure of the c2 domain of the human e3 ubiquitin-protein2 ligase nedd4-like protein
79 | d2cjsa1 |
| not modelled | 99.2 | 26 | Fold:C2 domain-like Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB) Family:PLC-like (P variant)
80 | c2r83B_ |
| not modelled | 99.2 | 26 | PDB header:endocytosis, exocytosis Chain: B: PDB Molecule:synaptotagmin-1; PDBTitle: crystal structure analysis of human synaptotagmin 1 c2a-c2b
81 | d1a81a1 |
| not modelled | 99.2 | 22 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
82 | d2shpa2 |
| not modelled | 99.2 | 30 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
83 | d1blja_ |
| not modelled | 99.2 | 34 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
84 | d2oq1a1 |
| not modelled | 99.2 | 31 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
85 | c2dlyA_ |
| not modelled | 99.2 | 37 | PDB header:transferase Chain: A: PDB Molecule:fyn-related kinase; PDBTitle: solution structure of the sh2 domain of murine fyn-related2 kinase
86 | c2b3rA_ |
| not modelled | 99.2 | 17 | PDB header:transferase Chain: A: PDB Molecule:phosphatidylinositol-4-phosphate 3-kinase c2 domain- PDBTitle: crystal structure of the c2 domain of class ii phosphatidylinositide2 3-kinase c2
87 | d1fhsa_ |
| not modelled | 99.2 | 27 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
88 | d2eyva1 |
| not modelled | 99.2 | 30 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
89 | c2dmgA_ |
| not modelled | 99.2 | 22 | PDB header:lipid binding protein Chain: A: PDB Molecule:kiaa1228 protein; PDBTitle: solution structure of the third c2 domain of kiaa12282 protein
90 | d2cs0a1 |
| not modelled | 99.2 | 26 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
91 | c2augB_ |
| not modelled | 99.2 | 28 | PDB header:signaling protein Chain: B: PDB Molecule:growth factor receptor-bound protein 14; PDBTitle: crystal structure of the grb14 sh2 domain
92 | c2eo3A_ |
| not modelled | 99.2 | 30 | PDB header:signaling protein Chain: A: PDB Molecule:crk-like protein; PDBTitle: solution structure of the sh2 domain from human crk-like2 protein
93 | d1a81e1 |
| not modelled | 99.2 | 25 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
94 | d1a81a2 |
| not modelled | 99.1 | 36 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
95 | d1pica_ |
| not modelled | 99.1 | 26 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
96 | c2ysxA_ |
| not modelled | 99.1 | 33 | PDB header:signaling protein Chain: A: PDB Molecule:signaling inositol polyphosphate phosphatase PDBTitle: solution structure of the human ship sh2 domain
97 | c1x6cA_ |
| not modelled | 99.1 | 23 | PDB header:signaling protein Chain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type PDBTitle: solution structures of the sh2 domain of human protein-2 tyrosine phosphatase shp-1
98 | d1wfja_ |
| not modelled | 99.1 | 20 | Fold:C2 domain-like Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB) Family:Synaptotagmin-like (S variant)
99 | d1csya_ |
| not modelled | 99.1 | 27 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
100 | c2cr4A_ |
| not modelled | 99.1 | 25 | PDB header:signaling protein Chain: A: PDB Molecule:sh3 domain-binding protein 2; PDBTitle: solution structure of the sh2 domain of human sh3bp2 protein
101 | d1nrva_ |
| not modelled | 99.1 | 23 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
102 | d1jyra_ |
| not modelled | 99.1 | 30 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
103 | c2enjA_ |
| not modelled | 99.1 | 14 | PDB header:transferase Chain: A: PDB Molecule:protein kinase c theta type; PDBTitle: solution sturcture of the c2 domain from human protein2 kinase c theta
104 | d1opka2 |
| not modelled | 99.1 | 31 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
105 | c1ka6A_ |
| not modelled | 99.1 | 23 | PDB header:immune system Chain: A: PDB Molecule:sh2 domain protein 1a; PDBTitle: sap/sh2d1a bound to peptide n-py
106 | d1ayaa_ |
| not modelled | 99.1 | 27 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
107 | d1qcfa2 |
| not modelled | 99.1 | 28 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
108 | d1xa6a2 |
| not modelled | 99.1 | 28 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
109 | d1rjaa_ |
| not modelled | 99.1 | 27 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
110 | c1cjyB_ |
| not modelled | 99.1 | 26 | PDB header:hydrolase Chain: B: PDB Molecule:protein (cytosolic phospholipase a2); PDBTitle: human cytosolic phospholipase a2
111 | d2shpa3 |
| not modelled | 99.1 | 28 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
112 | c2ci8A_ |
| not modelled | 99.1 | 25 | PDB header:translation Chain: A: PDB Molecule:cytoplasmic protein nck1; PDBTitle: sh2 domain of human nck1 adaptor protein - uncomplexed
113 | d1rpya_ |
| not modelled | 99.1 | 24 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
114 | c2el8A_ |
| not modelled | 99.1 | 20 | PDB header:signaling protein Chain: A: PDB Molecule:signal-transducing adaptor protein 2; PDBTitle: solution structure of the human stap2 sh2 domain
115 | d1w15a_ |
| not modelled | 99.1 | 23 | Fold:C2 domain-like Superfamily:C2 domain (Calcium/lipid-binding domain, CaLB) Family:Synaptotagmin-like (S variant)
116 | c2knoA_ |
| not modelled | 99.1 | 27 | PDB header:hydrolase Chain: A: PDB Molecule:tensin-like c1 domain-containing phosphatase; PDBTitle: nmr solution structure of sh2 domain of the human tensin like c12 domain containing phosphatase (tenc1)
117 | c3fdwA_ |
| not modelled | 99.1 | 22 | PDB header:lipid binding protein Chain: A: PDB Molecule:synaptotagmin-like protein 4; PDBTitle: crystal structure of a c2 domain from human synaptotagmin-2 like protein 4
118 | c3n5aA_ |
| not modelled | 99.0 | 25 | PDB header:protein transport Chain: A: PDB Molecule:synaptotagmin-7; PDBTitle: synaptotagmin-7, c2b-domain, calcium bound
119 | c2dcrA_ |
| not modelled | 99.0 | 25 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fes/fps; PDBTitle: fully automated solution structure determination of the fes2 sh2 domain
120 | c2fo0A_ |
| not modelled | 99.0 | 22 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform); PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase

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