|   |   |
239 | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | |
|
. | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . |  |  |
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
L | K | R | N | R | C | I | R | E | L | Y | D | T | E | K | N | Y | V | A | Q | A | L | V | T | I | I | K | T | F | Y | E | P | L | K | . |
. |
G | I | I | P | T | S | D | Y | N | I | I | F | G | N | I | E | E | I | N | V | L | H | T | A | L | L | A | D | L | E | Y | P | V | K | V | A | L | G | L | S | D | A | T | P |
| Query Conservation |   |
  |
|
|   |   |
|
|   |
|
|   |   |
|
|   |   |
|
|   |   |   |
|   |   |
|   |   |   |
|   |   |
|
|   | . | . |   |   |
|   |   |   |   |   |   |   |
|
|   |
|
|   |   |
|   |   |   |   |   |   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
| Template Conservation |   |
  |
|   |   |   |
|   |   |
|
|
|   |
|
|   |   |
|
|   |   | . |
|   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |
|   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |   |   | . | . | . | . | . | . | . | . | . |
| Template Sequence |   |
D | K | A | Y | F | I | A | K | E | V | S | T | T | E | R | T | Y | L | K | D | . |
L | E | V | I | T | S | W | F | Q | S | T | V | S | K | E | D | A | M | P | E | A | L | K | S | L | I | F | P | N | F | E | P | L | H | K | F | H | T | N | F | L | K | E | I | E | Q | R | L | A | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
| Template Known Secondary structure |   |
S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |  |
|
|
|
|
|  |  |  |  |  |  |  | T | T | T |
| S |
|  |  |  |  |  |  |  | S | T | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
539 | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | |
. | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|   |
|   |   |
317 | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
P | R | P | I | S | L | N | E | C | V | P | Q | T | I | G | E | V | F | I | K | Y | R | D | Q | F | L | A | Y | G | K | Y | C | S | N | L | P | D | S | R | K | L | S | N | E | L | L | K | T | N | E | F | I | S | R | N | I | N | E | L | T | A | Q | G | N | C | K | F | G | M | N | D | L | L | C | V | P | F | Q | R | L |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |
|
|   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |
|
|
|
|
|
| Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |
|   |   |
|
|
|
|
|
| Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
W | E | G | D | V | M | L | K | N | I | Q | G | M | K | H | L | A | A | H | L | W | K | H | S | E | A | L | E | A | L | E | N | G | I | K | S | S | R | R | L | E | N | F | C | R | D | F | E | L | Q | K | V | C | Y | L | P | L | N | T | F | L | L | R | P | L | H | R | L |
| Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . |  |
|
|  |  |  |  |  |  |  |  |  | G | G | G | S |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  | T | T | T | T |
|  |  |  |  |  |  |  |  |  |  |  | T | S | S | S |
|
| S |
| G | G | G | G | G | T |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|
|
|
|
|
|
|
|
|
|
|
|
609 | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . |
|   |
|   |   |
397 | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
T | K | Y | P | L | L | L | K | E | L | Q | K | K | T | D | L | A | S | P | D | R | K | S | L | E | E | A | V | E | V | M | E | D | V | C | N | Y | I | N | E | E | S | R | D | T | N | A | I | K | V | I | D | E | I | E | Q | S | I | T | D | L | S | M | P | L | N | V | K | L | H | D | Y | G | R | V | N | L | D | G | E |
| Query Conservation |   |
  |
|
|   |
|
|
|   |   |
|
|
|   |
|   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |   |   |
|
|
|   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|
|   |
|
|
|   |   |
|
|
|   |
|   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   | . | . | . | . | . |   |   |   |   |
|   |   |   |   |   |   |   |
| Template Sequence |   |
M | H | Y | K | Q | V | L | E | R | L | C | K | H | H | P | R | D | C | R | A | A | . |
. |
. |
. |
. |
. |
L | A | E | I | T | E | M | V | A | Q | L | H | G | T | M | I | K | M | E | N | F | Q | K | L | H | E | L | K | K | D | L | I | G | I | D | L | . |
. |
. |
. |
. |
V | V | P | G | R | E | F | I | R | L | G | S |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  | T | T | T |  |  |  |  |  |  |  |  |  |  |  |  | T | G | G | G | T |  |  | S |
|
|
| . | . | . | . | . |
|
| T | T |
|
|  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|  |  |  |
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . | . | . | 710 | |
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 720 | . | . | . | . | . | . | . | . | . | 730 | . | . | . | . | . | . | . | . | . | 740 | . | . | . | . | . | . | |
|
|
|
|
. | . | . | 750 | . | . | . | . | . | . | . | . |
|   |
|   |   |
477 | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
V | K | M | A | E | S | T | L | T | Q | A | G | K | P | K | Q | R | Y | I | F | L | F | D | K | V | I | V | V | C | K | A | A | N | K | V | M | A | A | K | T | T | G | A | S | A | R | T | N | T | F | T | Y | K | N | A | Y | V | M | S | E | L | T | I | D | K | N | A | S | L | D | V | K | S | G | G | T | I | T | R | R |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
| Template Conservation |   |
  |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |
|   |   |
|
|
|   |
|   |
|
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
| Template Sequence |   |
L | S | K | L | . |
. |
. |
. |
. |
S | G | K | G | L | Q | Q | R | M | F | F | L | F | N | D | V | L | L | Y | T | S | R | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
N | Q | F | K | V | H | G | Q | L | P | L | Y | G | M | T | I | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | S | E |
| Template Known Secondary structure |   |
 |  |  |  | . | . | . | . | . |
| S | S | S |  |  |  |  |  |  |  |  |  | S | S |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| S |  |  |  |  |  |  |  |  |
| S | S |
|  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |
|
| Template Predicted Secondary structure |   |
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
766 | . | . | . | |
|
|
|
|
770 | . | . | . | . | . | . | . | . | . | 780 | . | . | . | . | . | . | . | . | . | 790 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 800 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
810 | . | . |
|   |
|   |   |
557 | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . |
| Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
T | Q | Y | V | I | I | M | T | R | D | R | N | E | N | N | E | I | T | Q | L | T | F | Y | F | K | N | E | A | T | R | N | N | W | M | T | A | L | L | L | S | K | S | N | V | S | P | T |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |
|   |
|   |   | . | . | . | . | . | . |   |   |   |   |   |   |
|   |
|   |
|   |   |
|
|   |   |
|   |   |   |
|   |   |
|
|   |   |   |   |   |   |
| Template Sequence |   |
D | P | H | C | L | T | L | R | G | . |
. |
. |
. |
. |
. |
Q | R | Q | S | I | I | V | A | A | S | S | R | S | E | M | E | K | W | V | E | D | I | Q | M | A | I | D | L | A | E | T | M |
| Template Known Secondary structure |   |
|
|
|  |  |  |  |  |
| . | . | . | . | . | . | S | S |
|  |  |  |  |  |
| S | S | S | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
|
|  |
| Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |
| . | . | . | . | . | . |
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
817 | . | . | 820 | . | . | . | . | . | |
|
|
|
|
|
. | . | . | . | 830 | . | . | . | . | . | . | . | . | . | 840 | . | . | . | . | . | . | . | . | . | 850 | . | . | . | . | . | . | . |
|   |