Job Description Q45FX5 Confidence 100.00% Date Fri May 3 21:26:37 BST 2013 Rank 3 Aligned Residues 370 % Identity 31% Template c3bjiA_ PDB info PDB header:signaling protein Chain: A: PDB Molecule:proto-oncogene vav; PDBTitle: structural basis of promiscuous guanine nucleotide exchange2 by the t-cell essential vav1 Resolution 2.60 Å Model Dimensions (Å) X:87.238 Y:73.848 Z:42.318

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		236	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		T	P	T	L	K	R	N	R	C	I	R	E	L	Y	D	T	E	K	N	Y	V	A	Q	A	L	V	T	I	I	K	T	F	Y	E	P	L	K	G	I	I	P	T	S	D	Y	N	I	I	F	G	N	I	E	E	I	N	V	L	H	T	A	L	L	A	D	L	E	Y	P	V	K	V	A	L	G	L	S	D	A	T
Query Conservation
Alig confidence																							.																																																		.	.	.	.	.	.	.	.	.
Template Conservation																							.																																																		.	.	.	.	.	.	.	.	.
Template Sequence		T	E	Y	D	K	R	C	C	C	L	R	E	I	Q	Q	T	E	E	K	Y	T	.	D	T	L	G	S	I	Q	Q	H	F	L	K	P	L	Q	R	F	L	K	P	Q	D	I	E	I	I	F	I	N	I	E	D	L	L	R	V	H	T	H	F	L	K	E	M	K	E	A	L	G	.	.	.	.	.	.	.	.	.
Template Known Secondary structure																							.									T	T					T	T	T	S										T	T																					.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																							.																																																		.	.	.	.	.	.	.	.	.
Template SS confidence
		190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210		.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.
		316	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.		.	.	.	.	.	.	.	.	390	.	.	.	.
Predicted Secondary structure																																																																				.
Query SS confidence																																																																				.
Query Sequence		P	P	R	P	I	S	L	N	E	C	V	P	Q	T	I	G	E	V	F	I	K	Y	R	D	Q	F	L	A	Y	G	K	Y	C	S	N	L	P	D	S	R	K	L	S	N	E	L	L	K	T	N	E	F	I	S	R	N	I	N	E	L	T	A	Q	G	N	C	.	K	F	G	M	N	D	L	L	C	V	P	F	Q
Query Conservation																																																																				.
Alig confidence		.	.	.	.	.	.	.	.																																																											.
Template Conservation		.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	T	P	G	A	A	N	L	Y	Q	V	F	I	K	Y	K	E	R	F	L	V	Y	G	R	Y	C	S	Q	V	E	S	A	S	K	H	L	D	R	V	A	A	A	R	E	D	V	Q	M	K	L	E	E	C	S	Q	R	A	N	N	G	R	F	T	L	R	D	L	L	M	V	P	M	Q
Template Known Secondary structure		.	.	.	.	.	.	.	.	T	T	T	S	T	T	S								T	T	G	G	G																																							T	T	S	S							T
Template Predicted Secondary structure		.	.	.	.	.	.	.	.
Template SS confidence
										260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.
		395	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	L	T	K	Y	P	L	L	L	K	E	L	Q	K	K	T	D	L	A	S	P	D	R	K	S	L	E	E	A	V	E	V	M	E	D	V	C	N	Y	I	N	E	E	S	R	D	T	N	A	I	K	V	I	D	E	I	E	Q	S	I	T	D	L	S	M	P	L	N	V	K	L	H	D	Y	G	R	V	N	L	D
Query Conservation
Alig confidence																			.																																																	.	.	.	.
Template Conservation																			.																																																	.	.	.	.
Template Sequence		R	V	L	K	Y	H	L	L	L	Q	E	L	V	K	H	T	Q	.	E	A	M	E	K	E	N	L	R	L	A	L	D	A	M	R	D	L	A	Q	C	V	N	E	V	K	R	D	N	E	T	L	R	Q	I	T	N	F	Q	L	S	I	E	N	L	D	Q	S	.	.	.	.	L	A	H	Y	G	R	P	K	I	D
Template Known Secondary structure				T	T										T	T			.		S																																							S			S			S		.	.	.	.	G	G	G	G
Template Predicted Secondary structure																			.																																																	.	.	.	.
Template SS confidence
		332	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.		.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.					.	.	.	400	.	.	.	.	.	.
		475	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	E	V	K	M	A	E	S	T	L	T	Q	A	G	K	P	K	Q	R	Y	I	F	L	F	D	K	V	I	V	V	C	K	A	A	N	K	V	M	A	A	K	T	T	G	A	S	A	R	T	N	T	F	T	Y	K	N	A	Y	V	M	S	E	L	T	I	D	K	N	A	S	L	D	V	K	S	G	G	T	I	T
Query Conservation
Alig confidence										.	.	.																									.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation										.	.	.																									.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		G	E	L	K	I	T	S	V	.	.	.	E	R	R	S	K	M	D	R	Y	A	F	L	L	D	K	A	L	L	I	C	K	R	R	G	.	.	.	.	.	.	.	.	.	.	.	.	.	.	D	S	Y	D	L	K	D	F	V	N	L	H	S	F	Q	V	R	D	D	D	N	K	K	W	S	H	M	F	L	L	I
Template Known Secondary structure									S	.	.	.	S			S										S	S									S	.	.	.	.	.	.	.	.	.	.	.	.	.	.	S										G	G	G									S	T	T
Template Predicted Secondary structure										.	.	.																									.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		407	.	.	410	.	.	.	.				.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.															.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.
		555	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	R	T	Q	Y	V	I	I	M	T	R	D	R	N	E	N	N	E	I	T	Q	L	T	F	Y	F	K	N	E	A	T	R	N	N	W	M	T	A	L	L	L	S	K	S	N	V	S	P	T	D	Y	L	R	D	T	N	H	K	V	A	F	H	S	F	R	V	D	V	K	N	P	A	T	C	D	V	C	D	K	L
Query Conservation
Alig confidence					.	.	.	.	.	.	.	.	.	.	.	.	.	.																																			.													.	.	.	.
Template Conservation					.	.	.	.	.	.	.	.	.	.	.	.	.	.																																			.													.	.	.	.
Template Sequence		E	D	Q	.	.	.	.	.	.	.	.	.	.	.	.	.	.	G	A	Q	G	Y	E	L	F	F	K	T	R	E	L	K	K	K	W	M	E	Q	F	E	M	A	I	S	N	I	Y	P	E	N	A	.	T	A	N	G	H	D	F	Q	M	F	S	F	.	.	.	.	E	E	T	T	S	C	K	A	C	Q	M	L
Template Known Secondary structure			S	S	.	.	.	.	.	.	.	.	.	.	.	.	.	.	S	S								S	S																			S		T	T	T	.	T	G	G	G									.	.	.	.		S			B		T	T	T		S	B
Template Predicted Secondary structure					.	.	.	.	.	.	.	.	.	.	.	.	.	.																																			.													.	.	.	.
Template SS confidence
		475	.	.															.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.		.	.	.	.	.	.	.	.	520	.	.	.					.	.	.	.	.	.	530	.	.	.	.	.
		635	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		M	K	G	L	Q	Y	Q	G	Y	K	C	E	S	C	N	M	S	M	H	K	E	C	L	G	L	K	K	C	E	A
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	R	G	T	F	Y	Q	G	Y	R	C	H	R	C	R	A	S	A	H	K	E	C	L	G	R	V	P	P	C	G
Template Known Secondary structure				S	S	S							T	T	T						G	G	G	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		536	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.