Job Description Q45FX5 Confidence 100.00% Date Fri May 3 21:26:37 BST 2013 Rank 4 Aligned Residues 356 % Identity 22% Template c2dx1A_ PDB info PDB header:signaling protein Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 4; PDBTitle: crystal structure of rhogef protein asef Resolution 2.36 Å Model Dimensions (Å) X:70.854 Y:76.754 Z:46.240

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		187	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.				.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.				.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260
Predicted Secondary structure																												.	.	.																									.	.	.
Query SS confidence																												.	.	.																									.	.	.
Query Sequence		H	D	N	I	E	N	V	D	P	N	R	T	I	Y	G	P	I	T	S	A	D	P	E	E	Q	Q	.	.	.	S	E	Q	L	Y	D	R	I	V	T	N	R	K	P	S	M	N	E	N	D	L	Q	N	T	.	.	.	P	T	L	K	R	N	R	C	I	R	E	L	Y	D	T	E	K	N	Y	V	A	Q	A	L
Query Conservation																												.	.	.																									.	.	.
Alig confidence																												.	.	.																									.	.	.																							.
Template Conservation																																																																																.
Template Sequence		D	H	V	T	X	D	D	Q	E	L	G	F	K	A	G	D	V	I	E	V	X	D	A	T	N	R	E	W	W	W	G	R	V	A	D	G	E	G	W	F	P	A	S	F	V	R	L	R	V	N	Q	D	A	Q	S	S	K	D	Q	X	R	T	N	V	I	N	E	I	L	S	T	E	R	D	Y	I	K	H	.	L
Template Known Secondary structure			B					T	T	B			B		T	T										S	S	S							S	S							G	G	G					S																														.
Template Predicted Secondary structure																																																																																.
Template SS confidence
		133	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210		.
		261	.	.	.	.	.	.	.	.	270	.	.				.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.
Predicted Secondary structure														.	.	.
Query SS confidence														.	.	.
Query Sequence		V	T	I	I	K	T	F	Y	E	P	L	K	.	.	.	G	I	I	P	T	S	D	Y	N	I	I	F	G	N	I	E	E	I	N	V	L	H	T	A	L	L	A	D	L	E	Y	P	V	K	V	A	L	G	L	S	D	A	T	P	P	R	P	I	S	L	N	E	C	V	P	Q	T	I	G	E	V	F	I	K	Y
Query Conservation														.	.	.
Alig confidence														.	.	.																																					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		R	D	I	C	E	G	Y	V	R	Q	C	R	K	R	A	D	X	F	S	E	E	Q	L	R	T	I	F	G	N	I	E	D	I	Y	R	C	Q	K	A	F	V	K	A	L	E	Q	R	F	N	R	E	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	R	P	H	L	S	E	L	G	A	C	F	L	E	H
Template Known Secondary structure								T					T	T		T	T	T											T	T																	T	T			S	S	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	S	G	G	G										T
Template Predicted Secondary structure																																																					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		233	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.																.	.	.	.	.	.	290	.	.	.	.	.	.	.
		338	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.		.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.
Predicted Secondary structure																																														.
Query SS confidence																																														.
Query Sequence		R	D	Q	F	L	A	Y	G	K	Y	C	S	N	L	P	D	S	R	K	L	S	N	E	L	L	K	T	N	E	F	I	S	R	N	I	N	E	L	T	A	Q	G	N	C	.	K	F	G	M	N	D	L	L	C	V	P	F	Q	R	L	T	K	Y	P	L	L	L	K	E	L	Q	K	K	T	D	L	A	S	P	D
Query Conservation																																														.
Alig confidence																											.																			.
Template Conservation																											.
Template Sequence		Q	A	D	F	Q	I	Y	S	E	Y	C	N	N	H	P	N	A	C	V	E	L	S	R	L	T	.	K	L	S	K	Y	V	Y	F	F	E	A	C	R	L	L	Q	K	X	I	D	I	S	L	D	G	F	L	L	T	P	V	Q	K	I	C	K	Y	P	L	Q	L	A	E	L	L	K	Y	T	H	P	Q	H	R	D
Template Known Secondary structure							T																				.	T																T			S																											T	S		T	T		T	T
Template Predicted Secondary structure																											.
Template SS confidence
		298	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.		.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.
		417	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	K	S	L	E	E	A	V	E	V	M	E	D	V	C	N	Y	I	N	E	E	S	R	D	T	N	A	I	K	V	I	D	E	I	E	Q	S	I	T	D	L	S	M	P	L	N	V	K	L	H	D	Y	G	R	V	N	L	D	G	E	V	K	M	A	E	S	T	L	T	Q	A	G	K	P	K	Q	R	Y	I	F
Query Conservation
Alig confidence																																													.	.																						.	.	.
Template Conservation																																													.	.																						.	.	.
Template Sequence		F	K	D	V	E	A	A	L	H	A	X	K	N	V	A	Q	L	I	N	E	R	K	R	R	L	E	N	I	D	K	I	A	Q	W	Q	S	S	I	E	D	W	E	G	.	.	E	D	L	L	V	R	S	S	E	L	I	Y	S	G	E	L	T	R	V	T	Q	.	.	.	P	Q	A	K	S	Q	Q	R	X	F	F
Template Known Secondary structure																																							S	B	S			S	.	.	S																				S	.	.	.	S	S	S
Template Predicted Secondary structure																																													.	.																						.	.	.
Template SS confidence
		377	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.			420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440				.	.	.	.	.	.	.	.	.	450	.
		497	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	F	D	K	V	I	V	V	C	K	A	A	N	K	V	M	A	A	K	T	T	G	A	S	A	R	T	N	T	F	T	Y	K	N	A	Y	V	M	S	E	L	T	I	D	K	N	A	S	L	D	V	K	S	G	G	T	I	T	R	R	T	Q	Y	V	I	I	M	T	R	D	R	N	E	N	N	E	I	T	Q	L
Query Conservation
Alig confidence															.	.	.	.	.	.	.	.	.	.	.																														.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation															.	.	.	.	.	.	.	.	.	.	.																														.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		L	F	D	H	Q	L	I	Y	C	K	K	D	L	.	.	.	.	.	.	.	.	.	.	.	L	R	R	D	V	L	Y	Y	K	G	R	L	D	X	D	G	L	E	V	V	I	K	N	A	F	R	L	H	S	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	H
Template Known Secondary structure				T	T									T	.	.	.	.	.	.	.	.	.	.	.	T		T	T										T	T	T														.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure															.	.	.	.	.	.	.	.	.	.	.																														.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		452	.	.	.	.	.	.	.	460	.	.	.	.												.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.																											.
		577	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.
Predicted Secondary structure
Query SS confidence
Query Sequence		T	F	Y	F	K	N	E	A	T	R	N	N	W	M	T	A	L	L	L	S	K	S	N	V	S
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	L	C	T	R	K	P	E	Q	K	Q	R	W	L	K	A	F	A	R	E	R	E	Q	V	Q
Template Known Secondary structure						S
Template Predicted Secondary structure
Template SS confidence
		514	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D