|   |   |
171 | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
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| Query SS confidence |   |
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| Query Sequence |   |
F | I | R | Q | C | D | E | I | L | Y | W | I | R | E | K | E | T | Y | V | T | A | E | D | M | G | M | D | L | E | H | V | E | I | L | Q | R | K | F | D | D | F | L | K | E | L | G | N | H | Q | Y | R | I | N | E | I | N | Q | A | A | D | K | L | V | E | E | G | H | S | E | H | D | Q | I | Y | K | K | R | D | D | V |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
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|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
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| Alig confidence |   |
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| . | . | . | . | . | . | . | . | . | . | . | . |
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| Template Conservation |   |
  |   |   |   |
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|   |   |   |   |   |   |   |
|   |   |   |   |
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|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
|
| Template Sequence |   |
T | K | H | V | T | S | E | C | L | G | W | M | R | Q | Q | R | A | E | M | D | M | V | A | W | G | V | D | L | A | S | V | E | Q | H | I | N | S | H | R | G | I | H | N | S | I | G | D | Y | R | W | Q | L | D | K | I | K | A | D | L | R | . |
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E | K | S | A | I | Y | Q | L |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
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|
| . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
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|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
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184 | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | |
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. | . | . | . | . | . | 250 | . |
|   |
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251 | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
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|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
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| Query Sequence |   |
N | D | A | W | H | R | L | N | T | L | A | A | T | R | K | E | G | L | F | G | A | H | Q | V | Q | R | F | N | R | D | A | D | E | T | L | A | W | I | G | E | K | D | L | A | L | S | S | D | D | Y | G | R | D | L | N | N | V | Q | A | L | Q | R | K | H | E | G | T | E | R | D | L | A | A | L | E | G | K | M | L | Q |
| Query Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
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|   |   |   |   |   |   |
| Alig confidence |   |
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| Template Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
| . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
E | E | E | Y | E | N | L | L | K | A | S | F | E | R | M | D | H | L | . |
. |
. |
R | Q | L | Q | N | I | I | Q | A | T | S | R | E | I | M | W | I | N | D | C | E | E | E | E | L | L | Y | D | W | S | D | K | N | T | N | I | A | Q | K | Q | E | A | F | S | I | R | M | S | Q | L | E | V | K | E | K | E | L | N | K |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
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| S | T | T |
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| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
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|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
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|   |   |
252 | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | |
|
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270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . |
|   |
|   |   |
331 | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | |
|
|
. | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . |  |  |  |
| Query SS confidence |   |
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| . |
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| Query Sequence |   |
L | E | K | E | A | H | K | L | A | E | T | H | P | D | R | A | E | A | I | H | Q | K | N | D | D | T | K | A | A | W | N | A | L | K | E | K | A | Q | H | R | K | D | G | L | E | R | S | F | Q | L | H | R | F | L | A | D | Y | R | D | L | I | S | W | I | G | D | M | K | A | V | I | G | A | D | . |
. |
. |
E | L | A |
| Query Conservation |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   | . | . | . |   |   |   |
| Alig confidence |   |
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| . | . | . |
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| Template Conservation |   |
  |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
L | K | Q | E | S | D | Q | L | V | L | N | Q | H | P | A | S | D | K | I | E | A | Y | M | D | T | L | Q | T | Q | W | S | W | I | L | Q | I | T | K | C | I | D | V | H | L | K | E | N | A | A | Y | F | Q | F | F | E | E | A | Q | S | T | E | A | Y | L | K | G | L | Q | D | S | I | R | K | K | Y | P | C | D | K | N |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | T | T |
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
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| T | T |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
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|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
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|   |   |
329 | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . |
|   |
|   |   |
408 | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | |
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| Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
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|  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Query SS confidence |   |
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| Query Sequence |   |
K | D | V | A | G | A | E | A | L | L | E | S | H | Q | E | H | K | G | E | I | D | A | R | A | D | S | F | N | Q | T | A | S | A | G | Q | K | L | V | E | M | G | I | P | E | S | P | . |
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| Query Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Alig confidence |   |
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| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
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| Template Sequence |   |
M | P | L | Q | H | L | L | E | Q | I | K | E | L | E | K | E | R | E | K | I | L | E | Y | K | R | Q | V | Q | N | L | V | N | K | S | K | K | I | V | Q | L | K | P | R | N | P | D | Y | R | S | N | K | P | I | I | L | R | A | L | C | D | Y | K | Q | D | Q | K | I | V | H | K | G | D | E | C | I | L | K | D | N | N |
| Template Known Secondary structure |   |
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| G | G | G | S | T | T |
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| T | T |
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| S |
| Template Predicted Secondary structure |   |
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| Template SS confidence |   |
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409 | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . |
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454 | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . |
| Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
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| Query Sequence |   |
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E | V | Q | E | K | L | E | K | L | D | H | E | K | S | S | L | L | G | L | W | E | E | R | R | I | L | Y | E | Q | C | M | D | L | Q | L | F | Y | R | D | T | E | Q | A | E | T | W | M | N | K | Q | E |
| Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
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| Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
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| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
E | R | S | K | W | Y | V | T | G | P | G | G | V | D | M | L | V | P | S | V | G | L | I | I | P | P | P | N | P | L | A | V | D | L | S | C | K | I | E | Q | Y | Y | E | A | I | L | A | L | W | N | Q | L | Y | I | N | M | K | S | L | V | S | W | H | Y | C | M | I | D | I | E | K | I | R | A | M | T | I | A | K | L |
| Template Known Secondary structure |   |
S | S | S |  |  |  |  |  |
| S | S | S |
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|  |  |  |  | G | G | G |  |  |
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| S |
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| Template Predicted Secondary structure |   |
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| Template SS confidence |   |
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|   |   |
489 | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . |
|   |
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505 | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | |
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. | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
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| Query SS confidence |   |
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| Query Sequence |   |
A | F | L | A | N | T | D | L | G | D | S | L | D | S | V | E | H | L | I | K | K | H | E | D | F | E | K | S | . |
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L | A | A | Q | E | E | K | I | N | A | L | D | E | F | A | T | K | L | I | Q | G | Q | H |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
| Alig confidence |   |
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| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
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| Template Sequence |   |
K | T | M | R | Q | E | D | Y | M | K | T | I | A | D | L | E | L | H | Y | Q | E | F | I | R | N | S | Q | G | S | E | M | F | G | D | D | D | K | R | K | I | Q | S | Q | F | T | D | A | Q | K | H | Y | Q | T | L | V | I | Q | L | P |
| Template Known Secondary structure |   |
T | T | S |
| T | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S | S |
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|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
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| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
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| Template SS confidence |   |
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|   |   |
569 | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . |
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