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1940 | . | . | . | . | . | . | . | . | . | 1950 | . | . | . | . | . | . | . | . | . | 1960 | . | . | . | . | . | . | . | . | . | 1970 | . | . | . | . | . | . | . | . | . | 1980 | . | . | . | . | . | . | . | . | . | 1990 | . | . | . | . | . | . | . | . | . | 2000 | . | . | . | . | . | . | . | . | . | 2010 | |
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| Predicted Secondary structure |   |
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| Query SS confidence |   |
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| Query Sequence |   |
N | S | A | Y | L | Q | F | M | W | K | C | D | V | V | E | S | W | I | A | E | K | E | Q | Q | V | R | S | E | D | F | G | R | D | L | S | S | V | Q | I | L | L | T | K | Q | E | A | F | D | A | G | L | N | A | F | E | H | E | G | I | Q | R | I | T | E | L | K | D | Q | L | V | S | . |
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S | E | H | Q | Q | S | P |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
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|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   | . | . |   |   |   |   |   |   |   |
| Alig confidence |   |
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| Template Conservation |   |
  |   |   |   |
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| . |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
Q | L | R | W | Q | E | Y | R | E | L | V | L | L | L | L | Q | W | M | R | H | H | T | A | A | F | . |
E | E | R | F | P | S | S | F | E | E | I | E | I | L | W | S | Q | F | L | K | F | K | E | M | E | L | P | A | K | E | A | D | K | N | R | S | K | G | I | Y | Q | S | L | E | G | A | V | Q | A | G | Q | L | K | V |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |  |
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| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S | S |
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| Template Predicted Secondary structure |   |
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| Template SS confidence |   |
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305 | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | |
330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . |
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2018 | . | 2020 | . | . | . | . | . | . | . | . | . | 2030 | . | . | . | . | . | . | . | . | . | 2040 | . | . | . | . | . | . | . | . | . | 2050 | . | . | . | . | . | . | . | . | . | 2060 | . | . | . | . | . | . | . | . | . | 2070 | . | . | . | . | . | . | . | . | . | 2080 | . | . | . | . | . | . | . | . | . | 2090 | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
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| Query SS confidence |   |
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| Query Sequence |   |
A | I | E | K | R | H | T | N | V | I | Q | R | W | Q | N | L | L | A | H | S | E | A | R | R | Q | K | L | L | K | M | Q | Q | Q | F | K | Q | I | E | E | L | Y | L | A | F | A | K | K | A | S | T | F | N | S | W | F | E | N | A | E | E | D | L | T | D | P | V | R | C | N | S | L | E | E | I | R | A | L | R | D | A |
| Query Conservation |   |
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|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
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| Template Conservation |   |
  |   |   |   |   |   |   |   |
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|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
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|   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |
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| Template Sequence |   |
P | P | G | Y | H | P | L | D | V | E | K | E | W | G | K | L | H | V | A | I | L | E | R | E | K | Q | L | R | S | E | F | E | R | L | E | A | L | Q | R | I | V | T | K | L | Q | M | E | A | G | L | A | E | E | Q | L | N | Q | A | D | A | L | L | Q | S | D | V | . |
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. |
R | L | L | A | A | G | K | V | P | Q | R |
| Template Known Secondary structure |   |
| T | T |
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . |  |  | T | T | T | T |
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| S |
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| Template Predicted Secondary structure |   |
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| . | . | . |
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| Template SS confidence |   |
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|   |   |
385 | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | |
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. | . | . | . | . | . | . | . | . | 460 | . |
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2098 | . | 2100 | . | . | . | . | . | . | . | . | . | 2110 | . | . | . | . | . | . | . | . | . | 2120 | . | . | . | . | . | . | . | . | . | 2130 | . | . | . | . | . | . | . | . | . | 2140 | . | . | . | . | . | . | . | . | . | 2150 | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
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|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
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| Query Sequence |   |
H | G | E | F | Q | R | S | L | S | S | A | E | E | D | F | R | Q | L | Q | D | L | D | R | R | I | K | S | F | N | V | G | P | N | P | Y | T | W | F | T | M | D | A | L | E | D | T | W | R | N | L | Q | R | I | I | K | E | R |
| Query Conservation |   |
  |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |
| Alig confidence |   |
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| Template Conservation |   |
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|   |   |   |   |   |   |   |   |   |   |
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| Template Sequence |   |
A | G | E | V | E | R | D | L | D | K | A | D | S | M | I | R | L | L | F | N | D | V | Q | T | L | K | D | G | R | H | P | Q | G | E | Q | M | Y | R | R | V | Y | R | L | H | K | R | L | V | A | I | R | T | E | Y | N | L | R |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
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|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
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462 | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . |
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