Job Description Q23554 Confidence 100.00% Date Fri May 3 21:43:27 BST 2013 Rank 7 Aligned Residues 366 % Identity 32% Template c4fl2A_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase syk; PDBTitle: structural and biophysical characterization of the syk activation2 switch Resolution 2.19 Å Model Dimensions (Å) X:63.322 Y:88.315 Z:48.024

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		27	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.					.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.		.	.	.	.	.	.	100	.
Predicted Secondary structure																								.	.	.	.																																														.
Query SS confidence																								.	.	.	.																																														.
Query Sequence		H	Q	D	M	D	W	Y	H	G	L	L	P	R	A	D	I	N	T	L	L	E	N	.	.	.	.	D	G	D	F	L	V	R	T	S	H	I	V	G	Q	D	S	A	K	T	V	L	S	V	K	W	K	G	K	C	H	H	W	Q	L	Q	E	K	E	D	G	S	I	V	I	E	.	E	R	K	F	E	S	V	L
Query Conservation																								.	.	.	.																																														.
Alig confidence																								.	.	.	.										.	.	.	.																																	.
Template Conservation																																					.	.	.	.
Template Sequence		H	E	K	M	P	W	F	H	G	K	I	S	R	E	E	S	E	Q	I	V	L	I	G	S	K	T	N	G	K	F	L	I	R	A	R	.	.	.	.	D	N	N	G	S	Y	A	L	C	L	L	H	E	G	K	V	L	H	Y	R	I	D	K	D	K	T	G	K	L	S	I	P	E	G	K	K	F	D	T	L	W
Template Known Secondary structure		G	G	G	S	T	T	B			S												S	S	S			T	T								.	.	.	.		T	T	T									T	T											T	T	S				S	T	T				B	S	S
Template Predicted Secondary structure																																					.	.	.	.
Template SS confidence
		163	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.					.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.
		102	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.																	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.									.	.	.	.	.	.	150	.	.	.	.	.	.	.
Predicted Secondary structure																										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																			.	.	.	.	.	.	.	.
Query SS confidence																										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																			.	.	.	.	.	.	.	.
Query Sequence		D	M	V	T	T	L	R	M	K	R	L	P	V	S	A	N	C	P	A	L	L	L	N	P	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	I	N	K	Q	D	W	E	L	R	H	D	Q	I	K	L	G	K	M	.	.	.	.	.	.	.	.	L	G	E	G	A	F	G	G	V	Y	K	A	A	F
Query Conservation																										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																			.	.	.	.	.	.	.	.
Alig confidence																										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																			.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		Q	L	V	E	H	Y	S	Y	K	A	D	G	L	L	R	V	L	T	V	P	C	Q	K	I	G	T	Q	R	E	A	L	P	M	D	T	E	V	Y	E	S	P	Y	A	D	P	E	E	I	R	P	K	E	V	Y	L	D	R	K	L	L	T	L	E	D	K	E	L	G	S	G	N	F	G	T	V	K	K	G	Y	Y
Template Known Secondary structure								T	T	B		T	T	S	S	S				S	B				S				T	T			G	G	G	S	G	G	G	S		G	G	G	S	T	T	S				S	S	S	B			G	G	G												T	T
Template Predicted Secondary structure
Template SS confidence
		239	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.
		158	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	C	K	G	E	K	R	M	V	A	V	K	V	N	K	G	N	E	K	I	S	T	R	A	M	I	E	D	V	C	K	E	A	R	I	M	R	Q	Y	Q	H	P	N	V	V	C	F	F	G	V	C	V	E	K	E	P	I	M	L	V	M	E	L	A	S	Q	G	A	L	D	S	F	L	K	N	E	K	N	N	V
Query Conservation
Alig confidence																.	.																																				.																											.
Template Conservation																.	.																																				.																											.
Template Sequence		Q	M	K	K	V	V	K	T	V	A	V	K	I	L	.	.	K	N	E	A	N	D	P	A	L	K	D	E	L	L	A	E	A	N	V	M	Q	Q	L	D	N	P	Y	I	V	R	M	I	G	I	C	.	E	A	E	S	W	M	L	V	M	E	M	A	E	L	G	P	L	N	K	Y	L	Q	Q	N	R	H	.	V
Template Known Secondary structure				T	T											.	.		S	G	G	G		G	G	G																	T	T	B								.		S	S	S									T	T		B									T	T	.	S
Template Predicted Secondary structure																.	.																																				.																											.
Template SS confidence
		391	.	.	.	.	.	.	.	.	400	.	.	.	.			.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.		440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.		.
		238	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.		.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.
Predicted Secondary structure																																				.
Query SS confidence																																				.
Query Sequence		S	L	R	D	K	L	K	Y	S	F	D	A	S	K	G	L	E	Y	L	H	Q	H	G	C	I	H	R	D	V	A	A	R	N	F	.	L	M	H	K	N	V	V	K	I	T	D	F	G	L	S	K	Q	L	S	D	L	A	H	K	Y	K	L	K	D	I	Q	A	K	L	P	I	R	W	L	A	P	E	V	I	V
Query Conservation																																				.
Alig confidence																																				.																																	.
Template Conservation																																																																					.
Template Sequence		K	D	K	N	I	I	E	L	V	H	Q	V	S	M	G	M	K	Y	L	E	E	S	N	F	V	H	R	D	L	A	A	R	N	V	L	L	V	T	Q	H	Y	A	K	I	S	D	F	G	L	S	K	A	L	R	A	D	E	N	Y	Y	K	A	Q	T	H	G	K	.	W	P	V	K	W	Y	A	P	E	C	I	N
Template Known Secondary structure																							T	T				S			S	G	G	G						T	T							T	T					T	T								S		B	T	T	B	.		G	G	G	G
Template Predicted Secondary structure																																																																					.
Template SS confidence
		467	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.		.	.	.	.	.	.	540	.	.	.	.	.
		317	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		T	A	T	Y	T	F	K	S	D	V	Y	S	F	G	I	L	L	W	E	I	F	M	D	G	A	I	P	Y	P	G	M	K	L	A	E	V	K	Q	K	V	K	N	G	Y	R	M	D	A	P	D	R	M	P	A	F	V	R	N	I	M	I	S	Q	C	W	P	Q	N	P	E	D	R	G	N	M	N	E	I	R	L
Query Conservation
Alig confidence																																																													.
Template Conservation																																																													.
Template Sequence		Y	Y	K	F	S	S	K	S	D	V	W	S	F	G	V	L	M	W	E	A	F	S	Y	G	Q	K	P	Y	R	G	M	K	G	S	E	V	T	A	M	L	E	K	G	E	R	M	G	C	P	A	G	C	P	R	E	M	Y	D	L	.	M	N	L	C	W	T	Y	D	V	E	N	R	P	G	F	A	A	V	E	L
Template Known Secondary structure																							T	T	T			S	S	T	T												T	T							T	T									.					T		S	S	T	T	T	S
Template Predicted Secondary structure																																																													.
Template SS confidence
		546	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.		.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.
		397	.	.	400	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	M	E	S	V	L
Query Conservation
Alig confidence
Template Conservation
Template Sequence		R	L	R	N	Y	Y
Template Known Secondary structure
Template Predicted Secondary structure
Template SS confidence
		625	.	.	.	.	630

---

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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D