Job Description Q23554 Confidence 100.00% Date Fri May 3 21:43:27 BST 2013 Rank 114 Aligned Residues 263 % Identity 27% Template c4e1zA_ PDB info PDB header:transferase/transferase inhibitor Chain: A: PDB Molecule:non-receptor tyrosine-protein kinase tyk2; PDBTitle: structure of mouse tyk-2 complexed to a 3-aminoindazole inhibitor Resolution 2.50 Å

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		132	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.			.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																													.	.
Query SS confidence																													.	.
Query Sequence		E	L	R	H	D	Q	I	K	L	G	K	M	L	G	E	G	A	F	G	G	V	Y	K	A	A	F	Y	.	.	C	K	G	E	K	R	M	V	A	V	K	V	N	K	G	N	E	K	I	S	T	R	A	M	I	E	D	V	C	K	E	A	R	I	M	R	Q	Y	Q	H	P	N	V	V	C	F	F	G	V	C	V
Query Conservation																													.	.
Alig confidence																													.	.														.	.	.
Template Conservation																																												.	.	.
Template Sequence		V	F	H	K	R	Y	L	K	K	I	R	D	L	G	E	G	H	F	G	K	V	S	L	Y	C	Y	D	P	T	N	D	G	T	G	E	M	V	A	V	K	A	L	.	.	.	K	E	G	C	G	P	Q	L	R	S	G	W	Q	R	E	I	E	I	L	R	T	L	Y	H	E	H	I	V	K	Y	K	G	C	C	E
Template Known Secondary structure		B			G	G	G											S	S										T	T			S	S										.	.	.		T	T																						T	T	B
Template Predicted Secondary structure																																												.	.	.
Template SS confidence
		887	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.				.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.
		210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.		.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.
Predicted Secondary structure																																																																.
Query SS confidence																																																																.
Query Sequence		E	K	E	P	I	M	L	V	M	E	L	A	S	Q	G	A	L	D	S	F	L	K	N	E	K	N	N	V	S	L	R	D	K	L	K	Y	S	F	D	A	S	K	G	L	E	Y	L	H	Q	H	G	C	I	H	R	D	V	A	A	R	N	F	.	L	M	H	K	N	V	V	K	I	T	D	F	G	L	S	K	Q
Query Conservation																																																																.
Alig confidence																								.	.	.																																						.
Template Conservation																								.	.	.
Template Sequence		D	K	S	V	Q	L	V	M	E	Y	V	P	L	G	S	L	R	D	Y	L	P	R	.	.	.	H	C	V	G	L	A	Q	L	L	L	F	A	Q	Q	I	C	E	G	M	A	Y	L	H	A	Q	H	Y	I	H	R	A	L	A	A	R	N	V	L	L	D	N	D	R	L	V	K	I	G	D	F	G	L	A	K	A
Template Known Secondary structure													T	T							G	G	G	.	.	.	S																								T	T				S			S	G	G	G					G	G	G								T	T
Template Predicted Secondary structure																								.	.	.
Template SS confidence
		964	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.				.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040
		289	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.																.	.	.	350	.	.	.
Predicted Secondary structure																																																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		L	S	D	L	A	H	K	Y	K	L	K	D	I	Q	A	K	L	P	I	R	W	L	A	P	E	V	I	V	T	A	T	Y	T	F	K	S	D	V	Y	S	F	G	I	L	L	W	E	I	F	M	D	G	A	I	P	Y	P	G	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	M	K	L	A	E	V	K
Query Conservation																																																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence									.																																											.								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation									.																																											.
Template Sequence		V	P	E	G	H	E	Y	.	Y	R	V	R	E	D	G	D	S	P	V	F	W	Y	A	P	E	C	L	K	E	C	K	F	Y	Y	A	S	D	V	W	S	F	G	V	T	L	Y	E	L	L	T	.	Y	C	D	S	N	Q	S	P	H	T	K	F	T	E	L	I	G	H	T	Q	G	Q	M	T	V	L	R	L	T
Template Known Secondary structure				T	T		S		.							S	S	S		G	G	G								S																					T	.	T	T		T	T	S	S											S
Template Predicted Secondary structure									.																																											.
Template SS confidence
		1044	.	.	.	.	.	1050		.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.		.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.
		354	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Q	K	V	K	N	G	Y	R	M	D	A	P	D	R	M	P	A	F	V	R	N	I	M	I	S	Q	C	W	P	Q	N	P	E	D	R	G	N	M	N	E	I	R	L	A	M	E	S	V	L	D
Query Conservation
Alig confidence																								.
Template Conservation																								.
Template Sequence		E	L	L	E	R	G	E	R	L	P	R	P	D	R	C	P	C	E	I	Y	H	L	.	M	K	N	C	W	E	T	E	A	S	F	R	P	T	F	Q	N	L	V	P	I	L	Q	T	A	Q	E
Template Known Secondary structure							T							T	T									.					T		S	S	G	G	G	S
Template Predicted Secondary structure																								.
Template SS confidence
		1122	.	.	.	.	.	.	.	1130	.	.	.	.	.	.	.	.	.	1140	.	.	.		.	.	.	.	.	.	1150	.	.	.	.	.	.	.	.	.	1160	.	.	.	.	.	.	.	.	.	1170

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D