Job Description Q23554 Confidence 100.00% Date Fri May 3 21:43:27 BST 2013 Rank 70 Aligned Residues 239 % Identity 26% Template c3vw6B_ PDB info PDB header:transferase/transferase inhibitor Chain: B: PDB Molecule:mitogen-activated protein kinase kinase kinase 5; PDBTitle: crystal structure of human apoptosis signal-regulating kinase 1 (ask1)2 with imidazopyridine inhibitor Resolution 2.40 Å

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		130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	W	E	L	R	H	D	Q	I	K	L	G	K	M	L	G	E	G	A	F	G	G	V	Y	K	A	A	F	Y	C	K	G	E	K	R	M	V	A	V	K	V	N	K	G	N	E	K	I	S	T	R	A	M	I	E	D	V	C	K	E	A	R	I	M	R	Q	Y	Q	H	P	N	V	V	C	F	F	G	V	C	V
Query Conservation
Alig confidence																												.	.																		.	.	.	.	.	.	.	.	.	.
Template Conservation																												.	.																		.	.	.	.	.	.	.	.	.	.
Template Sequence		E	Y	D	Y	E	Y	D	E	N	G	D	R	V	V	L	G	K	G	T	Y	G	I	V	Y	A	G	.	.	R	D	L	S	N	Q	V	R	I	A	I	K	E	I	P	E	Q	.	.	.	.	.	.	.	.	.	.	P	L	H	E	E	I	A	L	H	K	H	L	K	H	K	N	I	V	Q	Y	L	G	S	F	S
Template Known Secondary structure							B		T	T	S	S	B							S	S	S						.	.			T	T	T													.	.	.	.	.	.	.	.	.	.										T	T				T	T	B
Template Predicted Secondary structure																												.	.																		.	.	.	.	.	.	.	.	.	.
Template SS confidence
		672	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.			.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.											.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.
		210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.			.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.			.	.	.	.	.	.	280	.	.	.	.	.
Predicted Secondary structure																														.	.																																					.	.
Query SS confidence																														.	.																																					.	.
Query Sequence		E	K	E	P	I	M	L	V	M	E	L	A	S	Q	G	A	L	D	S	F	L	K	N	E	K	N	N	V	.	.	S	L	R	D	K	L	K	Y	S	F	D	A	S	K	G	L	E	Y	L	H	Q	H	G	C	I	H	R	D	V	A	A	R	N	F	L	M	.	.	H	K	N	V	V	K	I	T	D	F	G	L
Query Conservation																														.	.																																					.	.
Alig confidence																														.	.																																					.	.
Template Conservation
Template Sequence		E	N	G	F	I	K	I	F	M	E	Q	V	P	G	G	S	L	S	A	L	L	R	S	K	W	G	P	L	K	D	N	E	Q	T	I	G	F	Y	T	K	Q	I	L	E	G	L	K	Y	L	H	D	N	Q	I	V	H	R	D	I	K	G	D	N	V	L	I	N	T	Y	S	G	V	L	K	I	S	D	F	G	T
Template Known Secondary structure			T	T										T	T		B								T	T				T	T																						T	T				S			S	G	G	G					T	T	T									S	S
Template Predicted Secondary structure
Template SS confidence
		746	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.
		286	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.			320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.			.	.	.	360	.
Predicted Secondary structure																																				.	.																																						.	.
Query SS confidence																																				.	.																																						.	.
Query Sequence		S	K	Q	L	S	D	L	A	H	K	Y	K	L	K	D	I	Q	A	K	L	P	I	R	W	L	A	P	E	V	I	V	T	A	T	.	.	Y	T	F	K	S	D	V	Y	S	F	G	I	L	L	W	E	I	F	M	D	G	A	I	P	Y	P	G	M	K	L	A	E	V	K	Q	K	V	.	.	K	N	G	Y	R
Query Conservation																																				.	.																																						.	.
Alig confidence							.	.	.	.	.	.	.	.	.	.	.	.	.	.																.	.																				.																		.	.
Template Conservation							.	.	.	.	.	.	.	.	.	.	.	.	.	.																																					.
Template Sequence		S	K	R	L	T	.	.	.	.	.	.	.	.	.	.	.	.	.	.	G	T	L	Q	Y	M	A	P	E	I	I	D	K	G	P	R	G	Y	G	K	A	A	D	I	W	S	L	G	C	T	I	I	E	M	A	T	.	G	K	P	P	F	Y	E	L	G	E	P	Q	A	A	M	F	K	V	G	M	F	K	V	H
Template Known Secondary structure							.	.	.	.	.	.	.	.	.	.	.	.	.	.			G	G	G										G	G	G		S																		.	S	S		T	T	G	G	G		S												T
Template Predicted Secondary structure							.	.	.	.	.	.	.	.	.	.	.	.	.	.																																					.
Template SS confidence
		826	.	.	.	830															.	.	.	.	.	.	.	.	.	840	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.		.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890
		362	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		M	D	A	P	D	R	M	P	A	F	V	R	N	I	M	I	S	Q	C	W	P	Q	N	P	E	D	R	G	N	M	N	E	I	R	L
Query Conservation
Alig confidence																.
Template Conservation																.
Template Sequence		P	E	I	P	E	S	M	S	A	E	A	K	A	F	.	I	L	K	C	F	E	P	D	P	D	K	R	A	C	A	N	D	L	L	V
Template Known Secondary structure						T	T	S								.					T		S		T	T	T	S								T
Template Predicted Secondary structure																.
Template SS confidence
		901	.	.	.	.	.	.	.	.	910	.	.	.	.		.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D