Job Description Q23554 Confidence 100.00% Date Fri May 3 21:43:27 BST 2013 Rank 72 Aligned Residues 256 % Identity 33% Template c3v5qB_ PDB info PDB header:transferase/transferase inhibitor Chain: B: PDB Molecule:nt-3 growth factor receptor; PDBTitle: discovery of a selective trk inhibitor with efficacy in rodent cancer2 tumor models Resolution 2.20 Å

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		131	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.		150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																					.
Query SS confidence																					.
Query Sequence		W	E	L	R	H	D	Q	I	K	L	G	K	M	L	G	E	G	A	F	.	G	G	V	Y	K	A	A	F	Y	C	K	G	E	K	R	M	V	A	V	K	V	N	K	G	N	E	K	I	S	T	R	A	M	I	E	D	V	C	K	E	A	R	I	M	R	Q	Y	Q	H	P	N	V	V	C	F	F	G	V	C	V
Query Conservation																					.
Alig confidence																					.							.	.															.	.	.	.
Template Conservation																												.	.															.	.	.	.
Template Sequence		Q	H	I	K	R	R	D	I	V	L	K	R	E	L	G	F	K	V	F	L	A	E	C	Y	N	L	.	.	S	P	T	K	D	K	M	L	V	A	V	K	A	L	.	.	.	.	K	D	P	T	L	A	A	R	K	D	F	Q	R	E	A	E	L	L	T	N	L	Q	H	E	H	I	V	K	F	Y	G	V	C	G
Template Known Secondary structure						G	G	G																		S		.	.		S	S	S	S										.	.	.	.		S																						T	T	B
Template Predicted Secondary structure																												.	.															.	.	.	.
Template SS confidence
		531	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.			.	.	.	560	.	.	.	.	.	.	.	.	.	570					.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.
		210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.		.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.
Predicted Secondary structure																																																																.
Query SS confidence																																																																.
Query Sequence		E	K	E	P	I	M	L	V	M	E	L	A	S	Q	G	A	L	D	S	F	L	K	N	E	K	N	N	V	S	L	R	D	K	L	K	Y	S	F	D	A	S	K	G	L	E	Y	L	H	Q	H	G	C	I	H	R	D	V	A	A	R	N	F	.	L	M	H	K	N	V	V	K	I	T	D	F	G	L	S	K	Q
Query Conservation																																																																.
Alig confidence				.	.																																																											.
Template Conservation				.	.
Template Sequence		D	P	.	.	L	I	M	V	F	E	Y	M	K	H	G	D	L	N	K	F	L	R	A	H	G	P	E	L	G	L	S	Q	M	L	H	I	A	S	Q	I	A	S	G	M	V	Y	L	A	S	Q	H	F	V	H	R	D	L	A	T	R	N	C	L	V	G	A	N	L	L	V	K	I	G	D	F	G	M	D	V	Y
Template Known Secondary structure				.	.									T	T									T	T																										T	T				S			S	G	G	G					G	G	G												S
Template Predicted Secondary structure				.	.
Template SS confidence
		609	610			.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.
		289	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	S	D	L	A	H	K	Y	K	L	K	D	I	Q	A	K	L	P	I	R	W	L	A	P	E	V	I	V	T	A	T	Y	T	F	K	S	D	V	Y	S	F	G	I	L	L	W	E	I	F	M	D	G	A	I	P	Y	P	G	M	K	L	A	E	V	K	Q	K	V	K	N	G	Y	R	M	D	A	P	D	R	M
Query Conservation
Alig confidence					.	.	.	.	.	.	.	.
Template Conservation					.	.	.	.	.	.	.	.
Template Sequence		S	T	D	.	.	.	.	.	.	.	.	Y	Y	R	T	M	L	P	I	R	W	M	P	P	E	S	I	M	Y	R	K	F	T	T	E	S	D	V	W	S	F	G	V	I	L	W	E	I	F	T	Y	G	K	Q	P	W	F	Q	L	S	N	T	E	V	I	E	C	I	T	Q	G	R	V	L	E	R	P	R	V	C
Template Known Secondary structure		G	G	G	.	.	.	.	.	.	.	.		B				B		G	G	G																												T	T	T	S			T	T	T	T	S												T							T	T
Template Predicted Secondary structure					.	.	.	.	.	.	.	.
Template SS confidence
		706	.	.									.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.
		369	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	A	F	V	R	N	I	M	I	S	Q	C	W	P	Q	N	P	E	D	R	G	N	M	N	E	I	R	L	A	M	E	S	V	L	D
Query Conservation
Alig confidence									.
Template Conservation									.
Template Sequence		P	K	E	V	Y	D	V	.	M	L	G	C	W	Q	R	E	P	Q	Q	R	L	N	I	K	E	I	Y	K	I	L	H	A	L	G	K
Template Known Secondary structure									.							S	S	G	G	G	S
Template Predicted Secondary structure									.
Template SS confidence
		796	.	.	.	800	.	.		.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D