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Job DescriptionQ23554
Confidence100.00%DateFri May 3 21:43:27 BST 2013
Rank202Aligned Residues253
% Identity22%Templatec3mtfB_
PDB info PDB header:transferaseChain: B: PDB Molecule:activin receptor type-1; PDBTitle: crystal structure of the acvr1 kinase in complex with a 2-2 aminopyridine inhibitor
Resolution2.15 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   136...140.........150.........160.........170.........180.........190.........200....... ..210.
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Query Sequence  DQIKLGKMLGEGAFGGVYKAAFYCKGEKRMVAVKVNKGNEKISTRAMIEDVCKEARIMRQYQHPNVVCFFGV. . . . CVEK
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Template Sequence  RDITLLECVGKGRYGEVWRGSW. . . . QGENVAVKIF. . . . . SSRDEKSWFRETELYNTVMLRHENILGFIASDMTSRHSS
Template Known Secondary structure  TTTT....TT.....
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TTB

TT
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   206...210.........220....... ..230....... ..240.........250.........260.........270......
 
   212.......220.........230.........240.........250.........260. ........270........ .280..
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Query Sequence  EPIMLVMELASQGALDSFLKNEKNNVSLRDKLKYSFDASKGLEYLHQHGC. . . . . . . . IHRDVAARNFLMHKNVV. KITD
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Template Sequence  TQLWLITHYHEMGSLYDYLQL. . TTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIAD
Template Known Secondary structure 

TT
B..

B
S
B
STT
B

S

SGGG
TTS


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   277..280.........290....... ..300.........310.........320.........330.........340.........350....
 
   283......290.........300.........310......... 320.........330.........340.........
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Query Sequence  FGLSKQLSDLAHKYKLKDIQAKLPIRWLAPEVIVTAT. . . . . . YTFKSDVYSFGILLWEIFMDGAIPYPGMKL. . . . . . .
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Template Sequence  LGLAVMHSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVAR. RMVSNGIVEDYKPPFYD
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TT
TTTT








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TT


TT
T.TB
BTTB





TTTT
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   355....360.........370.........380.........390.........400.........410...... ...420.........430...
 
   350.........360....... ..370.........380.........390.........400.
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Query Sequence  . . . . . . . . AEVKQKVKNGYRMDAPDR. . . . . . MPAFVRNIMISQCWPQNPEDRGNMNEIRLAMESV
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Template Sequence  VVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKL. MKECWYQNPSARLTALRIKKTLTKI
Template Known Secondary structure  TS
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TTS






GGGGGS.

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   434.....440.........450.........460.........470... ......480.........490........
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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