|   |   |
133 | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | |
. | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . |
| Predicted Secondary structure |   |
 |
|  |  |  |
|
|  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
L | R | H | D | Q | I | K | L | G | K | M | L | G | E | G | A | F | G | G | V | Y | K | A | A | F | Y | C | K | G | E | K | R | M | V | A | V | K | V | N | K | G | N | E | K | I | S | T | R | A | M | I | E | D | V | C | K | E | A | R | I | M | R | Q | Y | Q | . |
H | P | N | V | V | C | F | F | G | V | C | V | E | K |
| Query Conservation |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   | . |
|
|
|
|
|   |
|   |
|   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |
|
|   |
|   |
|
|   |
|
|   |
| . | . |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
F | N | N | F | Y | I | L | T | S | K | E | L | G | R | G | K | F | A | V | V | R | Q | C | . |
. |
I | S | K | S | T | G | Q | E | Y | A | A | K | F | L | K | K | R | R | R | G | Q | D | C | . |
. |
R | A | E | I | L | H | E | I | A | V | L | E | L | A | K | S | C | P | R | V | I | N | L | H | E | V | Y | E | N | T |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  | . | . |  |  | T | T | T |
|
|  |  |  |  |  |  |  |  | S |  |  | T | T |  |  |
| . | . |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
| T | T | B |
|
|  |  |  |  |  |  |
| S |
| Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  | . | . |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
28 | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | |
|
. | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | |
|
. | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . |
|   |
|   |   |
212 | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | |
. | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 |
| Predicted Secondary structure |   |
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
E | P | I | M | L | V | M | E | L | A | S | Q | G | A | L | D | S | F | L | K | N | . |
E | K | N | N | V | S | L | R | D | K | L | K | Y | S | F | D | A | S | K | G | L | E | Y | L | H | Q | H | G | C | I | H | R | D | V | A | A | R | N | F | L | M | H | K | N | V | V | K | I | T | D | F | G | L | S | K | Q | L | S |
| Query Conservation |   |
  |   |   |   |
|
|   |
|
|   |   |   |
|   |
|   |   |   |
|   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |   |
|
|
|
|
|
|   |   |
|
|
|   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
| Template Conservation |   |
  |   |   |   |   |
|   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |
| Template Sequence |   |
S | E | I | I | L | I | L | E | Y | A | A | G | G | E | I | F | S | L | C | L | P | E | L | A | E | M | V | S | E | N | D | V | I | R | L | I | K | Q | I | L | E | G | V | Y | Y | L | H | Q | N | N | I | V | H | L | D | L | K | P | Q | N | I | L | L | S | S | I | Y | P | L | G | D | I | K | I | . |
. |
. |
. |
. |
. |
| Template Known Secondary structure |   |
S |  |  |  |  |  |  |  |
|
| T | T |  |  | G | G | G | G | G | S | G | G | G |
| S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| B |
|
|
|
|
| G | G | G |  |  |  | S |
| B | T | T | B |
|
|  |  |  | . | . | . | . | . | . |
| Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
104 | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | |
|
|
|
|
|
|   |
|   |   |
291 | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | |
|
|
. | . |
| Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| . | . | . |
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
| Query Sequence |   |
D | L | A | H | K | Y | K | L | K | D | I | Q | A | K | L | P | I | R | W | L | A | P | E | V | I | V | T | A | T | Y | T | F | K | S | D | V | Y | S | F | G | I | L | L | W | E | I | F | M | D | G | A | I | P | Y | P | G | M | K | L | A | E | V | K | Q | K | V | K | N | G | Y | R | M | D | A | P | . |
. |
. |
D | R |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|   |
|   |
|
|   |
|   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |
| . | . | . |   |   |
| Alig confidence |   |
. | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
| Template Conservation |   |
. | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |
|
|
|
|
|   |   | . |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
. |
. |
. |
. |
V | D | F | G | M | S | R | K | I | M | G | T | P | E | Y | L | A | P | E | I | L | N | Y | D | P | I | T | T | A | T | D | M | W | N | I | G | I | I | A | Y | M | L | L | T | . |
H | T | S | P | F | V | G | E | D | N | Q | E | T | Y | L | N | I | S | Q | V | N | V | D | Y | S | E | E | T | F | S | S |
| Template Known Secondary structure |   |
. | . | . | . |
|
|
| T | T |
| B |
|
|
|
| S | G | G | G |
|
|  |  |  |  | T | T |
|
|
|
| T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
| S | S |
|
| S | S |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|
|  |  |  |  | T | T |
| Template Predicted Secondary structure |   |
. | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
| . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|
|
|
|
178 | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | |
. | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . |
|   |
|   |   |
368 | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
M | P | A | F | V | R | N | I | M | I | S | Q | C | W | P | Q | N | P | E | D | R | G | N | M | N | E | I | R | L |
| Query Conservation |   |
  |   |   |   |
|   |   |
|
|
|   |   |
|   |   |   |
|
|   |   |
|
|
|   |   |
|
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|   |   |   |   |   |
| . |
|   |   |   |
|   |   |
|
|   |   |
|
|
|   |   |
|
|
|   |
| Template Sequence |   |
V | S | Q | L | A | T | D | F | . |
I | Q | S | L | L | V | K | N | P | E | K | R | P | T | A | E | I | C | L | S |
| Template Known Secondary structure |   |
S |
|  |  |  |  |  |  | . |  |  |  |  | S |
| S | S | G | G | G | S |
|
|  |  |  |  |  | T |
| Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  | . |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
262 | . | . | . | . | . | . | . | |
270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . |
|   |