Job Description Q23554 Confidence 100.00% Date Fri May 3 21:43:27 BST 2013 Rank 212 Aligned Residues 245 % Identity 25% Template c3kvwA_ PDB info PDB header:transferase Chain: A: PDB Molecule:dual specificity tyrosine-phosphorylation-regulated kinase PDBTitle: crystal structure of dual-specificity tyrosine phosphorylation2 regulated kinase 2 (dyrk2) in complex with an indirubin ligand Resolution 2.28 Å

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		135	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.							.	200	.	.	.	.	.	.	.	.
Predicted Secondary structure																																																																		.	.	.	.	.	.
Query SS confidence																																																																		.	.	.	.	.	.
Query Sequence		H	D	Q	I	K	L	G	K	M	L	G	E	G	A	F	G	G	V	Y	K	A	A	F	Y	C	K	G	E	K	R	M	V	A	V	K	V	N	K	G	N	E	K	I	S	T	R	A	M	I	E	D	V	C	K	E	A	R	I	M	R	Q	Y	Q	H	.	.	.	.	.	.	P	N	V	V	C	F	F	G	V	C
Query Conservation																																																																		.	.	.	.	.	.
Alig confidence																							.	.																.	.	.	.	.																						.	.	.	.	.	.
Template Conservation																							.	.																.	.	.	.	.
Template Sequence		A	Y	R	Y	E	V	L	K	V	I	G	K	G	S	F	G	Q	V	V	K	A	.	.	Y	D	H	K	V	H	Q	H	V	A	L	K	M	V	R	.	.	.	.	.	N	E	K	R	F	H	R	Q	A	A	E	E	I	R	I	L	E	H	L	R	K	Q	D	K	D	N	T	M	N	V	I	H	M	L	E	N	F
Template Known Secondary structure		T	T	T										S	S	S							.	.			T	T	T	T										.	.	.	.	.	S																				T	T		T	T	S		S		B
Template Predicted Secondary structure																							.	.																.	.	.	.	.
Template SS confidence
		146	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.			.	.	.	170	.	.	.	.	.	.	.	.	.	180	.						.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.
		209	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.				.	.	280	.	.	.	.	.
Predicted Secondary structure																																																																							.	.	.
Query SS confidence																																																																							.	.	.
Query Sequence		V	E	K	E	P	I	M	L	V	M	E	L	A	S	Q	G	A	L	D	S	F	L	K	N	E	K	N	N	V	S	L	R	D	K	L	K	Y	S	F	D	A	S	K	G	L	E	Y	L	H	Q	H	G	C	I	H	R	D	V	A	A	R	N	F	L	M	H	K	N	V	.	.	.	V	K	I	T	D	F	G	L
Query Conservation																																																																							.	.	.
Alig confidence																																																																							.	.	.
Template Conservation
Template Sequence		T	F	R	N	H	I	C	M	T	F	E	L	L	S	M	N	L	Y	E	L	I	K	K	N	K	F	Q	G	F	S	L	P	L	V	R	K	F	A	H	S	I	L	Q	C	L	D	A	L	H	K	N	R	I	I	H	C	D	L	K	P	E	N	I	L	L	K	Q	Q	G	R	S	G	I	K	V	I	D	F	G	S
Template Known Secondary structure				T	T												B								T	T	T																										T				S			S	G	G	G				S	S	T	T	S									T	T
Template Predicted Secondary structure
Template SS confidence
		219	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.
		286	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.
Predicted Secondary structure																																																																																.	.
Query SS confidence																																																																																.	.
Query Sequence		S	K	Q	L	S	D	L	A	H	K	Y	K	L	K	D	I	Q	A	K	L	P	I	R	W	L	A	P	E	V	I	V	T	A	T	Y	T	F	K	S	D	V	Y	S	F	G	I	L	L	W	E	I	F	M	D	G	A	I	P	Y	P	G	M	K	L	A	E	V	K	Q	K	V	K	N	G	Y	R	M	D	.	.
Query Conservation																																																																																.	.
Alig confidence																	.	.	.	.	.	.	.	.																															.																									.	.
Template Conservation																	.	.	.	.	.	.	.	.																															.
Template Sequence		S	C	Y	E	H	Q	R	V	Y	T	I	Q	S	R	F	.	.	.	.	.	.	.	.	Y	R	A	P	E	V	I	L	G	A	R	Y	G	M	P	I	D	M	W	S	L	G	C	I	L	A	E	L	L	T	.	G	Y	P	L	L	P	G	E	D	E	G	D	Q	L	A	C	M	I	E	L	L	G	M	P	S	Q
Template Known Secondary structure					T	T									G	G	.	.	.	.	.	.	.	.	G								T	B				T																	.	S	S		S	S			S	S
Template Predicted Secondary structure																	.	.	.	.	.	.	.	.																															.
Template SS confidence
		299	300	.	.	.	.	.	.	.	.	.	310	.	.	.									.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.		.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.
																																																							364	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	A	P	D	R	M	P	A	F	V	R	N	I	M	I	S	Q	C	W	P	Q	N	P	E	D	R	G	N
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.													.
Template Conservation																																																																			.
Template Sequence		K	L	L	D	A	S	K	R	A	K	N	F	V	S	K	G	Y	P	R	Y	C	T	V	T	T	L	S	D	V	V	L	N	G	G	R	S	R	R	G	K	L	R	G	P	P	E	S	R	E	W	G	N	A	L	K	G	C	D	D	P	L	F	L	D	F	.	L	K	Q	C	L	E	W	D	P	A	V	R	M	T
Template Known Secondary structure						T	B	T	T					B					B	T	T	S																T	T						S	T	T		S						T	T	T										.					T		S	S	T	T	T	S
Template Predicted Secondary structure																																																																			.
Template SS confidence
		371	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.		.	.	.	.	440	.	.	.	.	.	.	.	.	.
		391	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		M	N	E	I	R	L
Query Conservation
Alig confidence
Template Conservation
Template Sequence		P	G	Q	A	L	R
Template Known Secondary structure							T
Template Predicted Secondary structure
Template SS confidence
		453	.	.	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D