Job Description Q23554 Confidence 100.00% Date Fri May 3 21:43:27 BST 2013 Rank 67 Aligned Residues 261 % Identity 33% Template c3eygA_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase; PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes Resolution 1.90 Å

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		129	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.			.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.
Predicted Secondary structure																																.	.
Query SS confidence																																.	.
Query Sequence		Q	D	W	E	L	R	H	D	Q	I	K	L	G	K	M	L	G	E	G	A	F	G	G	V	Y	K	A	A	F	Y	.	.	C	K	G	E	K	R	M	V	A	V	K	V	N	K	G	N	E	K	I	S	T	R	A	M	I	E	D	V	C	K	E	A	R	I	M	R	Q	Y	Q	H	P	N	V	V	C	F	F	G
Query Conservation																																.	.
Alig confidence																																.	.																	.	.	.	.	.	.	.	.
Template Conservation																																																		.	.	.	.	.	.	.	.
Template Sequence		D	P	T	H	F	E	K	R	F	L	K	R	I	R	D	L	G	E	G	H	F	G	K	V	E	L	C	R	Y	D	P	E	G	D	N	T	G	E	Q	V	A	V	K	S	L	K	P	H	.	.	.	.	.	.	.	.	I	A	D	L	K	K	E	I	E	I	L	R	N	L	Y	H	E	N	I	V	K	Y	K	G
Template Known Secondary structure			T	T	S			G	G	G											S	S										T	T	S	S	S		S												.	.	.	.	.	.	.	.													T				T	T	B
Template Predicted Secondary structure																																																		.	.	.	.	.	.	.	.
Template SS confidence
		866	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.									.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.
		207	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.		.	.	.	.	.	.	.	.	280	.	.	.	.	.
Predicted Secondary structure																																																																			.
Query SS confidence																																																																			.
Query Sequence		V	C	V	E	K	E	P	I	M	L	V	M	E	L	A	S	Q	G	A	L	D	S	F	L	K	N	E	K	N	N	V	S	L	R	D	K	L	K	Y	S	F	D	A	S	K	G	L	E	Y	L	H	Q	H	G	C	I	H	R	D	V	A	A	R	N	F	.	L	M	H	K	N	V	V	K	I	T	D	F	G	L
Query Conservation																																																																			.
Alig confidence									.																																																										.
Template Conservation									.
Template Sequence		I	C	T	E	N	G	I	.	K	L	I	M	E	F	L	P	S	G	S	L	K	E	Y	L	P	K	N	K	N	K	I	N	L	K	Q	Q	L	K	Y	A	V	Q	I	C	K	G	M	D	Y	L	G	S	R	Q	Y	V	H	R	D	L	A	A	R	N	V	L	V	E	S	E	H	Q	V	K	I	G	D	F	G	L
Template Known Secondary structure									.								T	T		B					T	G	G	G	T	T	T																							T	T				S			S	G	G	G						T	T								T	T
Template Predicted Secondary structure									.
Template SS confidence
		943	.	.	.	.	.	.		950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.
		286	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.																.	.	350
Predicted Secondary structure																																																																.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																																																.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		S	K	Q	L	S	D	L	A	H	K	Y	K	L	K	D	I	Q	A	K	L	P	I	R	W	L	A	P	E	V	I	V	T	A	T	Y	T	F	K	S	D	V	Y	S	F	G	I	L	L	W	E	I	F	M	D	G	A	I	P	Y	P	G	M	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	K	L	A
Query Conservation																																																																.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																			.	.	.																																		.									.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																			.	.	.																																		.
Template Sequence		T	K	A	I	E	T	D	K	E	T	V	K	D	D	R	D	S	.	.	.	P	V	F	W	Y	A	P	E	C	L	M	Q	S	K	F	Y	I	A	S	D	V	W	S	F	G	V	T	L	H	E	L	L	T	.	Y	C	D	S	D	S	S	P	M	A	L	F	L	K	M	I	G	P	T	H	G	Q	M	T	V	T
Template Known Secondary structure							T	T					S			T	T		.	.	.		G	G	G																													T	.	T	T		G	G	G												S			G	G	G
Template Predicted Secondary structure																			.	.	.																																		.
Template SS confidence
		1025	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.				.	.	.	.	.	.	.	.	1050	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.		.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.	.	.	1100
		351	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	V	K	Q	K	V	K	N	G	Y	R	M	D	A	P	D	R	M	P	A	F	V	R	N	I	M	I	S	Q	C	W	P	Q	N	P	E	D	R	G	N	M	N	E	I	R	L	A	M	E	S	V	L	D
Query Conservation
Alig confidence																											.
Template Conservation																											.
Template Sequence		R	L	V	N	T	L	K	E	G	K	R	L	P	C	P	P	N	C	P	D	E	V	Y	Q	L	.	M	R	K	C	W	E	F	Q	P	S	N	R	T	S	F	Q	N	L	I	E	G	F	E	A	L	L	K
Template Known Secondary structure									T	T							T	T									.				T			S	S	G	G	G	S												T	T
Template Predicted Secondary structure																											.
Template SS confidence
		1103	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.	.	.	.	.	.	.		.	.	1130	.	.	.	.	.	.	.	.	.	1140	.	.	.	.	.	.	.	.	.	1150	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D