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Job DescriptionQ23554
Confidence100.00%DateFri May 3 21:43:27 BST 2013
Rank94Aligned Residues251
% Identity31%Templatec3d4qA_
PDB info PDB header:transferaseChain: A: PDB Molecule:b-raf proto-oncogene serine/threonine-protein kinase; PDBTitle: pyrazole-based inhibitors of b-raf kinase
Resolution2.80 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   129130.........140.........150.........160.........170.........180.........190.........200........
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Query Sequence  QDWELRHDQIKLGKMLGEGAFGGVYKAAFYCKGEKRMVAVKVNKGNEKISTRAMIEDVCKEARIMRQYQHPNVVCFFGVC
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Template Sequence  DDWEIPDGQITVGQRIGSGSFGTVYKGKW. . . . . HGDVAVKML. . NVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMG. Y
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   448.450.........460.........470...... ...480..... ....490.........500.........510........ .
 
   209210.........220.........230.........240.........250.........260.........270. ........280.......
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Query Sequence  VEKEPIMLVMELASQGALDSFLKNEKNNVSLRDKLKYSFDASKGLEYLHQHGCIHRDVAARNF. LMHKNVVKITDFGLSK
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Template Sequence  STKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLAT
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   520.........530.........540.........550.........560.........570.........580.........590.........
 
   288.290.........300.........310......... 320.........330.........340.........350. ........360...
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Query Sequence  QLSDLAHKYKLKDIQAKLPIRWLAPEVIVTAT. . . YTFKSDVYSFGILLWEIFMDGAIPYPGMKLAE. VKQKVKNGYRMD
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Template Sequence  VLSG. . . . . . . . . . . . . . SILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMT. GQLPYSNINNRDQIIFMVGRGYLSP
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   600... ......610.........620.........630......... 640.........650.........660....
 
   364.....370.........380.........390.........400...
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Query Sequence  . . . . APDRMPAFVRNIMISQCWPQNPEDRGNMNEIRLAMESVLD
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Template Sequence  DLSKVRSNCPKAMKRL. MAECLKKKRDERPLFPQILASIELLAR
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   677..680.........690.. .......700.........710.........
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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