Job Description Q23554 Confidence 100.00% Date Fri May 3 21:43:27 BST 2013 Rank 5 Aligned Residues 383 % Identity 31% Template c2h8hA_ PDB info PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: src kinase in complex with a quinazoline inhibitor Resolution 2.20 Å Model Dimensions (Å) X:69.374 Y:76.647 Z:49.301

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		7	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.					.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.						.	.	.	.
Predicted Secondary structure																																												.	.	.	.																										.	.	.	.	.
Query SS confidence																																												.	.	.	.																										.	.	.	.	.
Query Sequence		S	H	R	A	Q	K	T	V	E	A	S	L	R	S	D	G	T	R	K	K	H	Q	D	M	D	W	Y	H	G	L	L	P	R	A	D	I	N	T	L	L	E	N	.	.	.	.	D	G	D	F	L	V	R	T	S	H	I	V	G	Q	D	S	A	K	T	V	L	S	V	K	W	.	.	.	.	.	K	G	K	C
Query Conservation																																												.	.	.	.																										.	.	.	.	.
Alig confidence																				.	.																							.	.	.	.																.	.	.								.	.	.	.	.
Template Conservation																				.	.																																										.	.	.
Template Sequence		S	T	G	Q	T	G	Y	I	P	S	N	Y	V	A	P	S	D	S	.	.	I	Q	A	E	E	W	Y	F	G	K	I	T	R	R	E	S	E	R	L	L	L	N	A	E	N	P	R	G	T	F	L	V	R	E	S	E	T	T	K	G	A	.	.	.	Y	C	L	S	V	S	D	F	D	N	A	K	G	L	N	V
Template Known Secondary structure		T	T								G	G	G				T	T	S	.	.	G	G	G	S	T	T	B			S											T		T	T			T	T								S	S	S	T	T		.	.	.										T	T	T
Template Predicted Secondary structure																				.	.																																										.	.	.
Template SS confidence
		125	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.			.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.				.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.
		78	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.		.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.							.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150
Predicted Secondary structure																		.																																	.	.	.	.	.	.
Query SS confidence																		.																																	.	.	.	.	.	.
Query Sequence		H	H	W	Q	L	Q	E	K	E	D	G	S	I	V	I	E	.	E	R	K	F	E	S	V	L	D	M	V	T	T	L	R	M	K	R	L	P	V	S	A	N	C	P	A	L	L	L	N	P	.	.	.	.	.	.	I	N	K	Q	D	W	E	L	R	H	D	Q	I	K	L	G	K	M	L	G	E	G	A	F	G
Query Conservation																		.																																	.	.	.	.	.	.
Alig confidence																		.																																	.	.	.	.	.	.
Template Conservation
Template Sequence		K	H	Y	K	I	R	K	L	D	S	G	G	F	Y	I	T	S	R	T	Q	F	N	S	L	Q	Q	L	V	A	Y	Y	S	K	H	A	D	G	L	C	H	R	L	T	T	V	C	P	T	S	K	P	Q	T	Q	G	L	A	K	D	A	W	E	I	P	R	E	S	L	R	L	E	V	K	L	G	Q	G	C	F	G
Template Known Secondary structure							B		.			S						T	T				S	S													T	T	S	S	S														S	S	S	S	T	T		S	B			G	G	G											S	S
Template Predicted Secondary structure
Template SS confidence
		200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.
		151	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230
Predicted Secondary structure
Query SS confidence
Query Sequence		G	V	Y	K	A	A	F	Y	C	K	G	E	K	R	M	V	A	V	K	V	N	K	G	N	E	K	I	S	T	R	A	M	I	E	D	V	C	K	E	A	R	I	M	R	Q	Y	Q	H	P	N	V	V	C	F	F	G	V	C	V	E	K	E	P	I	M	L	V	M	E	L	A	S	Q	G	A	L	D	S	F	L
Query Conservation
Alig confidence										.	.	.																		.	.	.	.	.																											.
Template Conservation										.	.	.																		.	.	.	.	.																											.
Template Sequence		E	V	W	M	G	T	W	N	.	.	.	G	T	T	R	V	A	I	K	T	L	K	P	G	T	M	S	P	.	.	.	.	.	E	A	F	L	Q	E	A	Q	V	M	K	K	L	R	H	E	K	L	V	Q	L	Y	A	V	V	S	.	E	E	P	I	Y	I	V	T	E	Y	M	S	K	G	S	L	L	D	F	L
Template Known Secondary structure									T	.	.	.	T	T										T	T	S	S			.	.	.	.	.																T	T	B									.	S	S	S									T	T
Template Predicted Secondary structure										.	.	.																		.	.	.	.	.																											.
Template SS confidence
		280	.	.	.	.	.	.	.				.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.						.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330		.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
		231	.	.	.	.	.		.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.		.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.
Predicted Secondary structure								.																																									.
Query SS confidence								.																																									.
Query Sequence		K	N	E	K	N	N	.	V	S	L	R	D	K	L	K	Y	S	F	D	A	S	K	G	L	E	Y	L	H	Q	H	G	C	I	H	R	D	V	A	A	R	N	F	L	M	H	K	N	.	V	V	K	I	T	D	F	G	L	S	K	Q	L	S	D	L	A	H	K	Y	K	L	K	D	I	Q	A	K	L	P	I	R
Query Conservation								.																																									.
Alig confidence								.																																									.																											.	.	.
Template Conservation																																																																												.	.	.
Template Sequence		K	G	E	T	G	K	Y	L	R	L	P	Q	L	V	D	M	A	A	Q	I	A	S	G	M	A	Y	V	E	R	M	N	Y	V	H	R	D	L	R	A	A	N	I	L	V	G	E	N	L	V	C	K	V	A	D	F	G	L	A	R	L	I	E	D	N	E	Y	T	A	R	Q	G	A	K	F	.	.	.	P	I	K
Template Known Secondary structure		S					T	T																							T	T				S			S	G	G	G					G	G	G							T	T	S	T	T	T								T	T		S	T	T	S	.	.	.		G	G
Template Predicted Secondary structure																																																																												.	.	.
Template SS confidence
		351	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.				.	.	.
		309	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		W	L	A	P	E	V	I	V	T	A	T	Y	T	F	K	S	D	V	Y	S	F	G	I	L	L	W	E	I	F	M	D	G	A	I	P	Y	P	G	M	K	L	A	E	V	K	Q	K	V	K	N	G	Y	R	M	D	A	P	D	R	M	P	A	F	V	R	N	I	M	I	S	Q	C	W	P	Q	N	P	E	D	R
Query Conservation
Alig confidence																																																																					.
Template Conservation																																																																					.
Template Sequence		W	T	A	P	E	A	A	L	Y	G	R	F	T	I	K	S	D	V	W	S	F	G	I	L	L	T	E	L	T	T	K	G	R	V	P	Y	P	G	M	V	N	R	E	V	L	D	Q	V	E	R	G	Y	R	M	P	C	P	P	E	C	P	E	S	L	H	D	L	.	M	C	Q	C	W	R	K	E	P	E	E	R
Template Known Secondary structure		G	S																											T	T	T	T			S	S	T	T												T	T							T	T									.					T		S	S	G	G	G	S
Template Predicted Secondary structure																																																																					.
Template SS confidence
		428	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.		.	.	.	.	.	500	.	.	.	.	.	.
		389	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	N	M	N	E	I	R	L	A	M	E	S	V	L	D	G	K	V	A
Query Conservation
Alig confidence
Template Conservation
Template Sequence		P	T	F	E	Y	L	Q	A	F	L	E	D	Y	F	T	S	T	E	P
Template Known Secondary structure													T	S	S				S
Template Predicted Secondary structure
Template SS confidence
		507	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D