Job Description Q23554 Confidence 100.00% Date Fri May 3 21:43:27 BST 2013 Rank 1 Aligned Residues 383 % Identity 30% Template c2fo0A_ PDB info PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform); PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase Resolution 2.27 Å Model Dimensions (Å) X:72.600 Y:78.951 Z:48.845

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		7	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.			.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.
Predicted Secondary structure																																												.	.
Query SS confidence																																												.	.
Query Sequence		S	H	R	A	Q	K	T	V	E	A	S	L	R	S	D	G	T	R	K	K	H	Q	D	M	D	W	Y	H	G	L	L	P	R	A	D	I	N	T	L	L	E	N	.	.	D	G	D	F	L	V	R	T	S	H	I	V	G	Q	D	S	A	K	T	V	L	S	V	K	W	K	G	K	C	H	H	W	Q	L	Q	E
Query Conservation																																												.	.
Alig confidence																				.	.																							.	.																.	.	.
Template Conservation																				.	.																																								.	.	.
Template Sequence		T	K	N	G	Q	G	W	V	P	S	N	Y	I	T	P	V	N	S	.	.	L	E	K	H	S	W	Y	H	G	P	V	S	R	N	A	A	E	Y	L	L	S	S	G	I	N	G	S	F	L	V	R	E	S	E	S	S	P	G	Q	.	.	.	R	S	I	S	L	R	Y	E	G	R	V	Y	H	Y	R	I	N	T
Template Known Secondary structure			T	T							G	G	G				T	T	S	.	.	G	G	G	S	T	T														T	S	S	S		T	T								S	S	S	T	T		.	.	.								T	T
Template Predicted Secondary structure																				.	.																																								.	.	.
Template SS confidence
		123	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140			.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.				180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.
		85	.	.	.	.	90	.	.	.		.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.										.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.
Predicted Secondary structure											.																																		.	.	.	.	.	.	.	.	.
Query SS confidence											.																																		.	.	.	.	.	.	.	.	.
Query Sequence		K	E	D	G	S	I	V	I	E	.	E	R	K	F	E	S	V	L	D	M	V	T	T	L	R	M	K	R	L	P	V	S	A	N	C	P	A	L	L	L	N	P	I	.	.	.	.	.	.	.	.	.	N	K	Q	D	W	E	L	R	H	D	Q	I	K	L	G	K	M	L	G	E	G	A	F	G	G	V	Y	K
Query Conservation											.																																		.	.	.	.	.	.	.	.	.
Alig confidence											.																																		.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		A	S	D	G	K	L	Y	V	S	S	E	S	R	F	N	T	L	A	E	L	V	H	H	H	S	T	V	A	D	G	L	I	T	T	L	H	Y	P	A	P	K	R	N	K	P	T	V	Y	G	V	S	P	N	Y	D	K	W	E	M	E	R	T	D	I	T	M	K	H	K	L	G	G	G	Q	Y	G	E	V	Y	E
Template Known Secondary structure			T	T	S				S	S	T	T			B	S	S													T	T	S	S	S															S	S	S		S	S	T	T			B			G	G	G							S	G	G	G	T	T	S	S
Template Predicted Secondary structure
Template SS confidence
		198	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.
		155	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.
Predicted Secondary structure																																																																																	.
Query SS confidence																																																																																	.
Query Sequence		A	A	F	Y	C	K	G	E	K	R	M	V	A	V	K	V	N	K	G	N	E	K	I	S	T	R	A	M	I	E	D	V	C	K	E	A	R	I	M	R	Q	Y	Q	H	P	N	V	V	C	F	F	G	V	C	V	E	K	E	P	I	M	L	V	M	E	L	A	S	Q	G	A	L	D	S	F	L	K	N	E	.
Query Conservation																																																																																	.
Alig confidence			.	.																						.	.	.	.	.																																																			.
Template Conservation			.	.																						.	.	.	.	.
Template Sequence		G	.	.	V	W	K	K	Y	S	L	T	V	A	V	K	T	L	K	E	D	T	M	E	V	.	.	.	.	.	E	E	F	L	K	E	A	A	V	M	K	E	I	K	H	P	N	L	V	Q	L	L	G	V	C	T	R	E	P	P	F	Y	I	I	T	E	F	M	T	Y	G	N	L	L	D	Y	L	R	E	C	N
Template Known Secondary structure			.	.			G	G	G	T										T	T	S				.	.	.	.	.																T	T	B									S	S	S	S									T	T		B								S
Template Predicted Secondary structure			.	.																						.	.	.	.	.
Template SS confidence
		278			.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.						300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
		234	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.		.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.
Predicted Secondary structure																																								.
Query SS confidence																																								.
Query Sequence		K	N	N	V	S	L	R	D	K	L	K	Y	S	F	D	A	S	K	G	L	E	Y	L	H	Q	H	G	C	I	H	R	D	V	A	A	R	N	F	.	L	M	H	K	N	V	V	K	I	T	D	F	G	L	S	K	Q	L	S	D	L	A	H	K	Y	K	L	K	D	I	Q	A	K	L	P	I	R	W	L	A	P
Query Conservation																																								.
Alig confidence																																								.																																.	.	.
Template Conservation																																																																								.	.	.
Template Sequence		R	Q	E	V	N	A	V	V	L	L	Y	M	A	T	Q	I	S	S	A	M	E	Y	L	E	K	K	N	F	I	H	R	N	L	A	A	R	N	C	L	V	G	E	N	H	L	V	K	V	A	D	F	G	L	S	R	L	M	T	G	D	T	Y	T	A	H	A	G	A	K	F	.	.	.	P	I	K	W	T	A	P
Template Known Secondary structure		T	T	T	S																						T	T				S			S	G	G	G					G	G	G							T	T						S	S							T	T				.	.	.		G	G	G
Template Predicted Secondary structure																																																																								.	.	.
Template SS confidence
		351	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420				.	.	.	.	.	.	.
		313	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	V	I	V	T	A	T	Y	T	F	K	S	D	V	Y	S	F	G	I	L	L	W	E	I	F	M	D	G	A	I	P	Y	P	G	M	K	L	A	E	V	K	Q	K	V	K	N	G	Y	R	M	D	A	P	D	R	M	P	A	F	V	R	N	I	M	I	S	Q	C	W	P	Q	N	P	E	D	R	G	N	M	N
Query Conservation
Alig confidence																																																																	.
Template Conservation																																																																	.
Template Sequence		E	S	L	A	Y	N	K	F	S	I	K	S	D	V	W	A	F	G	V	L	L	W	E	I	A	T	Y	G	M	S	P	Y	P	G	I	D	L	S	Q	V	Y	E	L	L	E	K	D	Y	R	M	E	R	P	E	G	C	P	E	K	V	Y	E	L	.	M	R	A	C	W	Q	W	N	P	S	D	R	P	S	F	A
Template Known Secondary structure																											T	T	S			S	S	T	T												T	T							T	T									.					T		S	S	G	G	G	S
Template Predicted Secondary structure																																																																	.
Template SS confidence
		428	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490		.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.
		393	.	.	.	.	.	.	400	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	I	R	L	A	M	E	S	V	L	D	G	K
Query Conservation
Alig confidence
Template Conservation
Template Sequence		E	I	H	Q	A	F	E	T	M	F	Q	E	S
Template Known Secondary structure									T	S	S	S	S	S
Template Predicted Secondary structure
Template SS confidence
		507	.	.	510	.	.	.	.	.	.	.	.	.

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D