Job Description Q23554 Confidence 100.00% Date Fri May 3 21:43:27 BST 2013 Rank 6 Aligned Residues 375 % Identity 31% Template c2c0iA_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: src family kinase hck with bound inhibitor a-420983 Resolution 2.30 Å Model Dimensions (Å) X:67.598 Y:75.949 Z:49.862

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		7	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.					.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.						.	.	.	.	.
Predicted Secondary structure																																												.	.	.	.																									.	.	.	.	.
Query SS confidence																																												.	.	.	.																									.	.	.	.	.
Query Sequence		S	H	R	A	Q	K	T	V	E	A	S	L	R	S	D	G	T	R	K	K	H	Q	D	M	D	W	Y	H	G	L	L	P	R	A	D	I	N	T	L	L	E	N	.	.	.	.	D	G	D	F	L	V	R	T	S	H	I	V	G	Q	D	S	A	K	T	V	L	S	V	K	.	.	.	.	.	W	K	G	K	C
Query Conservation																																												.	.	.	.																									.	.	.	.	.
Alig confidence																				.	.																							.	.	.	.																.	.	.							.	.	.	.	.
Template Conservation																				.	.																																										.	.	.
Template Sequence		A	T	R	K	E	G	Y	I	P	S	N	Y	V	A	R	V	D	S	.	.	L	E	T	E	E	W	F	F	K	G	I	S	R	K	D	A	E	R	Q	L	L	A	P	G	N	M	L	G	S	F	M	I	R	D	S	E	T	T	K	G	S	.	.	.	Y	S	L	S	V	R	D	Y	D	P	R	Q	G	D	T	V
Template Known Secondary structure		T	T								G	G	G				T	T	S	.	.	G	G	G	S	T	T			T	T											T	S	T	T			T	T								S	S	S	T	T		.	.	.										T	T	T
Template Predicted Secondary structure																				.	.																																										.	.	.
Template SS confidence
		100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.			.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.				.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.
		78	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.		.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.						130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.
Predicted Secondary structure																		.																																					.	.	.	.	.
Query SS confidence																		.																																					.	.	.	.	.
Query Sequence		H	H	W	Q	L	Q	E	K	E	D	G	S	I	V	I	E	.	E	R	K	F	E	S	V	L	D	M	V	T	T	L	R	M	K	R	L	P	V	S	A	N	C	P	A	L	L	L	N	P	I	N	K	Q	.	.	.	.	.	D	W	E	L	R	H	D	Q	I	K	L	G	K	M	L	G	E	G	A	F	G	G
Query Conservation																		.																																					.	.	.	.	.
Alig confidence																		.																																					.	.	.	.	.
Template Conservation
Template Sequence		K	H	Y	K	I	R	T	L	D	N	G	G	F	Y	I	S	P	R	S	T	F	S	T	L	Q	E	L	V	D	H	Y	K	K	G	N	D	G	L	C	Q	K	L	S	V	P	C	M	S	S	K	P	Q	K	P	W	E	K	D	A	W	E	I	P	R	E	S	L	K	L	E	K	K	L	G	A	G	Q	F	G	E
Template Known Secondary structure							B			S	T	T				S	S	T	T	S			S	S								T	T	S	S		S	S		S	S				S	B												T	T		S	B			G	G	G											T	T
Template Predicted Secondary structure
Template SS confidence
		175	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.
		152	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	Y	K	A	A	F	Y	C	K	G	E	K	R	M	V	A	V	K	V	N	K	G	N	E	K	I	S	T	R	A	M	I	E	D	V	C	K	E	A	R	I	M	R	Q	Y	Q	H	P	N	V	V	C	F	F	G	V	C	V	E	K	E	P	I	M	L	V	M	E	L	A	S	Q	G	A	L	D	S	F	L	K
Query Conservation
Alig confidence									.	.	.																		.	.	.	.	.																												.
Template Conservation									.	.	.																		.	.	.	.	.																												.
Template Sequence		V	W	M	A	T	Y	N	.	.	.	K	H	T	K	V	A	V	K	T	M	K	P	G	S	M	S	V	.	.	.	.	.	E	A	F	L	A	E	A	N	V	M	K	T	L	Q	H	D	K	L	V	K	L	H	A	V	V	T	K	.	E	P	I	Y	I	I	T	E	F	M	A	K	G	S	L	L	D	F	L	K
Template Known Secondary structure								T	.	.	.	T	T												S	S			.	.	.	.	.												T				T	T	B									S	.	S	S									T	T		B
Template Predicted Secondary structure									.	.	.																		.	.	.	.	.																												.
Template SS confidence
		255	.	.	.	.	260	.				.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.						.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.		.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.
		232		.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.		.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.
Predicted Secondary structure			.																																															.
Query SS confidence			.																																															.
Query Sequence		N	.	E	K	N	N	V	S	L	R	D	K	L	K	Y	S	F	D	A	S	K	G	L	E	Y	L	H	Q	H	G	C	I	H	R	D	V	A	A	R	N	F	L	M	H	K	N	V	V	.	K	I	T	D	F	G	L	S	K	Q	L	S	D	L	A	H	K	Y	K	L	K	D	I	Q	A	K	L	P	I	R	W
Query Conservation			.																																															.
Alig confidence			.																																															.										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		S	D	E	G	S	K	Q	P	L	P	K	L	I	D	F	S	A	Q	I	A	E	G	M	A	F	I	E	Q	R	N	Y	I	H	R	D	L	R	A	A	N	I	L	V	S	A	S	L	V	C	K	I	A	D	F	G	L	A	R	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	V	I	P	I	K	W
Template Known Secondary structure		S	T	T	G	G	G																							T	T				S			S	G	G	G					T	T								T	T	G	G	G	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	T			G	G	G
Template Predicted Secondary structure																																																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		326	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.																	.	.	.	.	.	.
		310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	A	P	E	V	I	V	T	A	T	Y	T	F	K	S	D	V	Y	S	F	G	I	L	L	W	E	I	F	M	D	G	A	I	P	Y	P	G	M	K	L	A	E	V	K	Q	K	V	K	N	G	Y	R	M	D	A	P	D	R	M	P	A	F	V	R	N	I	M	I	S	Q	C	W	P	Q	N	P	E	D	R	G
Query Conservation
Alig confidence																																																																				.
Template Conservation																																																																				.
Template Sequence		T	A	P	E	A	I	N	F	G	S	F	T	I	K	S	D	V	W	S	F	G	I	L	L	M	E	I	V	T	Y	G	R	I	P	Y	P	G	M	S	N	P	E	V	I	R	A	L	E	R	G	Y	R	M	P	R	P	E	N	C	P	E	E	L	Y	N	I	.	M	M	R	C	W	K	N	R	P	E	E	R	P
Template Known Secondary structure		S																												T	T	T			S	S	T	T												T	T							T	T									.					T		S	S	G	G	G	S
Template Predicted Secondary structure																																																																				.
Template SS confidence
		403	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.		.	470	.	.	.	.	.	.	.	.	.	480	.
		390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		N	M	N	E	I	R	L	A	M	E	S	V	L	D	G	K	V	A	A	S	N	N	R
Query Conservation
Alig confidence
Template Conservation
Template Sequence		T	F	E	Y	I	Q	S	V	L	D	D	F	Y	T	A	T	E	S	Q	E	E	I	P
Template Known Secondary structure												T	T	T	S		G	G	G
Template Predicted Secondary structure
Template SS confidence
		482	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D