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Job DescriptionQ20933
Confidence100.00%DateFri May 3 21:32:28 BST 2013
Rank254Aligned Residues262
% Identity26%Templatec3c1xA_
PDB info PDB header:transferaseChain: A: PDB Molecule:hepatocyte growth factor receptor; PDBTitle: crystal structure of the tyrosine kinase domain of the2 hepatocyte growth factor receptor c-met in complex with a3 pyrrolotriazine based inhibitor
Resolution2.17 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   106...110.... .....120.........130........ .140.........150.........160.........170.........180..
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Query Sequence  QSWELNHAD. . ITMTKVLGEGAFGEVKLGTLKMGS. TTVDVAIKVAKLEKVTKEQIKEIITEARLMRGFDHKNVVKCYGV
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Template Sequence  QHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGE. VSQFLTEGIIMKDFSHPNVLSLLGI
Template Known Secondary structure  TTTB

STT

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   1067..1070.........1080.........1090.........1100.........1110.........1120 .........1130.........1140.....
 
   183......190.........200 .........210.........220.........230.........240..... ....250.........
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Query Sequence  AAIDEPLLVVMELVPGGA. . LDKYLQKNSSVQWPEKLDIIAQVAAGLAYIHSKNIIHRDIAARNI. LYGKGVAKVSDFGL
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Template Sequence  CLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKFLASKKFVHRDLAARNCMLDEKFTVKVADFLP
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   1146...1150.........1160.........1170.........1180.........1190.........1200.........1210.........1220.....
 
   260.........270.........280.........290.........300.........310.........320.........330.........
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Query Sequence  SRVGTEYQMDPSKRVPIRWLSPETIVSFLYTPQTDVFAFSILCWEVIENGAQPYPEMLVVQVHQKVGRDDYRMPISQKAP
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Template Sequence  VK. . . . . . . . . . . . . . . . WMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGR. RLLQPEYCP
Template Known Secondary structure  GG................GS




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   1247. .1250.........1260.........1270.........1280.........1290.........1300 .........
 
   340.........350.........360.........370.........380.....
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Query Sequence  AMLADVIKKCWIRDPQQRPTMSQVVQMMYEITGKKDKTSVNKSTGQ
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Template Sequence  DPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNAT
Template Known Secondary structure  T
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   1310.........1320.........1330.........1340.........1350.....
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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