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Job DescriptionQ20933
Confidence100.00%DateFri May 3 21:32:28 BST 2013
Rank115Aligned Residues258
% Identity29%Templatec3v5qB_
PDB info PDB header:transferase/transferase inhibitorChain: B: PDB Molecule:nt-3 growth factor receptor; PDBTitle: discovery of a selective trk inhibitor with efficacy in rodent cancer2 tumor models
Resolution2.20 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   108.110.........120...... ...130.........140.........150.........160.........170.........180......
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Query Sequence  WELNHADITMTKVLGEGAF. GEVKLGTLKMGSTTVDVAIKVAKLEKVTKEQIKEIITEARLMRGFDHKNVVKCYGVAAID
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Template Sequence  QHIKRRDIVLKRELGFKVFLAECYNL. . SPTKDKMLVAVKALKDP. . TLAARKDFQREAELLTNLQHEHIVKFYGVC. . G
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   531........540.........550...... ...560.........570... ......580.........590.........600... .
 
   187..190.........200........ .210.........220.........230.........240..... ....250.........260....
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Query Sequence  EPLLVVMELVPGGALDKYLQKN. SSVQWPEKLDIIAQVAAGLAYIHSKNIIHRDIAARNI. LYGKGVAKVSDFGLSRVGT
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Template Sequence  DPLIMVFEYMKHGDLNKFLRAHGPELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMD. . . V
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   609610.........620.........630.........640.........650.........660.........670.........680.... .
 
   265....270.........280.........290.........300.........310.........320.........330.........340....
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Query Sequence  EYQMDPSKRVPIRWLSPETIVSFLYTPQTDVFAFSILCWEVIENGAQPYPEMLVVQVHQKVGRDDYRMPISQKAPAMLAD
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Template Sequence  YSTDYYRTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQ. GRVLERPRVCPKEVYD
Template Known Secondary structure  SGGG
B


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   705....710.........720.........730.........740.........750.........760....... ..770.........780...
 
   345....350.........360.........370.....
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Query Sequence  VIKKCWIRDPQQRPTMSQVVQMMYEITGKKD
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Template Sequence  VMLGCWQREPQQRLNIKEIYKILHALGKATP
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   802.......810.........820.........830..
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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