Return to main results Retrieve Phyre Job Id

Job DescriptionQ20933
Confidence100.00%DateFri May 3 21:32:28 BST 2013
Rank168Aligned Residues240
% Identity34%Templatec3k54A_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase btk; PDBTitle: structures of human bruton's tyrosine kinase in active and inactive2 conformations suggests a mechanism of activation for tec family3 kinases.
Resolution1.94 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   106...110.........120.........130.........140.........150.........160.........170.........180.....
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Query Sequence  QSWELNHADITMTKVLGEGAFGEVKLGTLKMGSTTVDVAIKVAKLEKVTKEQIKEIITEARLMRGFDHKNVVKCYGVAAI
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Template Sequence  GSWEIDPKDLTFLKELGTGQFGVVKYGKWRGQY. . . DVAIKMIK. . . . . . . . . . EFIEEAKVMMNLSHEKLVQLYGVCTK
Template Known Secondary structure  GGGB

GGGSTTSS
TTT...

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TT


TTB


S
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   393......400.........410.........420..... ....430... ......440.........450.........
 
   186...190.........200..... ....210.........220.........230.........240..... ....250.........260...
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Query Sequence  DEPLLVVMELVPGGALDKYL. QKNSSVQWPEKLDIIAQVAAGLAYIHSKNIIHRDIAARNI. LYGKGVAKVSDFGLSRVG
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Template Sequence  QRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGFP. . .
Template Known Secondary structure  SSS


TT
GGG


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SGGG
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   467..470.........480.........490.........500.........510.........520.........530.........540...
 
   264.....270.........280.........290.........300.........310.........320.........330.........340...
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Query Sequence  TEYQMDPSKRVPIRWLSPETIVSFLYTPQTDVFAFSILCWEVIENGAQPYPEMLVVQVHQKVGRDDYRMPISQKAPAMLA
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Template Sequence  . . . . . . . . . . . . VRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQ. GLRLYRPHLASEKVY
Template Known Secondary structure  ............GGG





TTS

TTTTS
T.T





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   561........570.........580.........590.........600.........610.. .......620.......
 
   344.....350.........360.........370....
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Query Sequence  DVIKKCWIRDPQQRPTMSQVVQMMYEITGKK
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Template Sequence  TIMYSCWHEKADERPTFKILLSNILDVMDEE
Template Known Secondary structure  TT
SSGGGS


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   628.630.........640.........650........
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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