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Job DescriptionQ20933
Confidence100.00%DateFri May 3 21:32:28 BST 2013
Rank210Aligned Residues231
% Identity25%Templatec3o96A_
PDB info PDB header:transferaseChain: A: PDB Molecule:rac-alpha serine/threonine-protein kinase; PDBTitle: crystal structure of human akt1 with an allosteric inhibitor
Resolution2.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   108.110.........120.........130.........140.........150.........160.........170.........180.......
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Query Sequence  WELNHADITMTKVLGEGAFGEVKLGTLKMGSTTVDVAIKVAKLEKVTKEQIKEIITEARLMRGFDHKNVVKCYGVAAIDE
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Template Sequence  KQVTMNEFEYLKLLGKGTFGKVILVKEKATGR. . YYAMKILK. . . . . . . . . KEVIVANRVLQNSRHPFLTALKYSFQTHD
Template Known Secondary structure  T


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   112.......120.........130.........140... ......150. ........160.........170.........180
 
   188.190.........200.........210.........220.........230... ......240..... ....250.........260.....
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Query Sequence  PLLVVMELVPGGALDKYLQKNSSVQWPEKLDIIAQVAAGLAYIHSK. NIIHRDIAARNI. LYGKGVAKVSDFGLSRVGTE
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Template Sequence  RLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLC. . . . .
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   222.......230.........240.........250.........260.........270.........280.........290......
 
   266...270.........280.........290.........300.........310.........320.........330.........340.....
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Query Sequence  YQMDPSKRVPIRWLSPETIVSFLYTPQTDVFAFSILCWEVIENGAQPYPEMLVVQVHQKVGRDDYRMPISQKAPAMLADV
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Template Sequence  . . . . . . . . KEPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMC. GRLPFYNQDHEKLFELILMEE. . IRFPRTLGPEAKSL
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   297..300.........310.........320.........330 .........340.........350. ........360.....
 
   346...350....... ..360.....
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Query Sequence  IKKCWIRDPQQR. . . . . PTMSQVVQ
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Template Sequence  LSGLLKKDPKQRLGGGSEDAKEIMQ
Template Known Secondary structure  T
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   380.........390.........400....
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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