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Job DescriptionQ20933
Confidence100.00%DateFri May 3 21:32:28 BST 2013
Rank76Aligned Residues265
% Identity27%Templatec3lxnA_
PDB info PDB header:transferaseChain: A: PDB Molecule:non-receptor tyrosine-protein kinase tyk2; PDBTitle: structural and thermodynamic characterization of the tyk2 and jak32 kinase domains in complex with cp-690550 and cmp-6
Resolution2.50 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   106...110.........120.........130..... ....140.........150.........160.........170.........180...
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Query Sequence  QSWELNHADITMTKVLGEGAFGEVKLGTLK. . MGSTTVDVAIKVAKLEKVTKEQIKEIITEARLMRGFDHKNVVKCYGVA
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Template Sequence  DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD. AGPQHRSGWKQEIDILRTLYHEHIIKYKGCC
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   888.890.........900.........910.........920.........930..... ....940.........950.........960......
 
   184.... .190.........200.........210.........220.........230.........240.........250 .........260
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Query Sequence  AIDEP. . LLVVMELVPGGALDKYLQKNSSVQWPEKLDIIAQVAAGLAYIHSKNIIHRDIAARNILYGKG. VAKVSDFGLS
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Template Sequence  EDAGAASLQLVMEYVPLGSLRDYLPR. HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA
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   967..970.........980.........990.. .......1000.........1010.........1020.........1030.........1040.....
 
   261........270.........280.........290.........300.........310..... ....320......
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Query Sequence  RVGTEYQMDPSKRVPIRWLSPETIVSFLYTPQTDVFAFSILCWEVIENGAQPYPE. . . . . . . . . . . . . . MLVVQVHQKVG
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Template Sequence  KAVPEGHEYRVGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT. HCDSSQSPPTKFLELIGIAQGQMTVLRLTELL
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   1046...1050.........1060.........1070.........1080.........1090.. .......1100.........1110.........1120....
 
   327..330.........340.........350.........360.........370...
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Query Sequence  RDDYRMPISQKAPAMLADVIKKCWIRDPQQRPTMSQVVQMMYEITGK
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Template Sequence  ERGERLPRPDKCPAEVYHLMKNCWETEASFRPTFENLIPILKTVHEK
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   11291130.........1140.........1150.........1160.........1170.....
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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