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Job DescriptionQ20933
Confidence100.00%DateFri May 3 21:32:28 BST 2013
Rank7Aligned Residues363
% Identity30%Templatec4fl2A_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase syk; PDBTitle: structural and biophysical characterization of the syk activation2 switch
Resolution2.19 Å
Model Dimensions (Å)X:63.118 Y:92.183 Z:46.005

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


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Query Sequence  MEINEQPFFHGLLPREEVKLLL. . . . QKNGDYLMRTSEPQGQARHLIISVMQNETSQEVAHYVIRTS. DGAYSITDKIKF
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Template Sequence  TAHEKMPWFHGKISREESEQIVLIGSKTNGKFLIRARDNNGS. . . YALCLLHEGK. . . VLHYRIDKDKTGKLSIPEGKKF
Template Known Secondary structure  S
GGGSTTB

S

SSS

TT
TTT...TT...
TTS
STT


B
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   161........170.........180.........190.........200.. .......210.. .......220.........230....
 
   76...80.........90...... ...100.........110.........120 .........130
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Query Sequence  GTLTELVNHHKQAKISEEVAS. . . . . . . . . . . . . . . . . SVLVNPIGRQSWELNHADITMTKV. . . . . . . . LGEGAFGEVK
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Template Sequence  DTLWQLVEHYSYKADGLLRVLTVPCQKIGTQREALPMDTEVYESPYADPEEIRPKEVYLDRKLLTLEDKELGSGNFGTVK
Template Known Secondary structure  SSTTB
TTSSS


SB


S


TT

GGGSGGGS
GGGSTTS


SSSB

GGGTT
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   235....240.........250.........260.........270.........280.........290.........300.........310....
 
   131........140.........150.........160.........170.........180.........190.........200.........210
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Query Sequence  LGTLKMGSTTVDVAIKVAKLEKVTKEQIKEIITEARLMRGFDHKNVVKCYGVAAIDEPLLVVMELVPGGALDKYLQKNSS
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Template Sequence  KGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGIC. EAESWMLVMEMAELGPLNKYLQQNRH
Template Known Secondary structure  TT
SGGG
GGG


TTB

.SSS

TT
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TT
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   387..390.........400.........410.........420.........430......... 440.........450.........460.....
 
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Query Sequence  VQWPEKLDIIAQVAAGLAYIHSKNIIHRDIAARNI. LYGKGVAKVSDFGLSRVGTEY. . . . QMDPSKRVPIRWLSPETIV
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Template Sequence  VKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECIN
Template Known Secondary structure  S
TT


S

SGGGTT

TTTT

S
BTTB
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   466...470.........480.........490.........500.........510.........520.........530.........540.....
 
   286...290.........300.........310.........320.........330.........340.........350.........360.....
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Query Sequence  SFLYTPQTDVFAFSILCWEVIENGAQPYPEMLVVQVHQKVGRDDYRMPISQKAPAMLADVIKKCWIRDPQQRPTMSQVVQ
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Template Sequence  YYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAML. EKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVEL
Template Known Secondary structure 



TTT

SSTT

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TT

T
SSTTTS

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   546...550.........560.........570.........580..... ....590.........600.........610.........620....
 
   366...370.
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Query Sequence  MMYEIT
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Template Sequence  RLRNYY
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   625....630
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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