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Job DescriptionQ20933
Confidence100.00%DateFri May 3 21:32:28 BST 2013
Rank278Aligned Residues243
% Identity20%Templatec2pvmA_
PDB info PDB header:transferaseChain: A: PDB Molecule:casein kinase ii subunit alpha; PDBTitle: structure-based design of pyrazolo[1,5-a][1,3,5]triazine2 derivatives as potent inhibitors of protein kinase ck2
Resolution2.00 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   113......120.........130.........140.........150.........160.........170.........180........ .190
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Query Sequence  ADITMTKVLGEGAFGEVKLGTLKMGSTTVDVAIKVAKLEKVTKEQIKEIITEARLMRGFDHKNVVKCYGVAAIDEP. . LL
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Template Sequence  DDYEVVRKVGRGKYSEVFEGINVNNNE. . KCIIKILKPVK. . . . . KKKIKREIKILQNLGGPNIVKLLDIVRDQHSKTPS
Template Known Secondary structure  GG
SSTTT

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S

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TTB


TTT

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   37..40.........50.........60... ......70.... .....80.........90.........100.........
 
   191........200.........210.........220.........230.........240.........250 .........260........
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Query Sequence  VVMELVPGGALDKYLQKNSSVQWPEKLDIIAQVAAGLAYIHSKNIIHRDIAARNILYGKG. . VAKVSDFGLSRVGTEYQM
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Template Sequence  LIFEYVNNTDFKVLYPT. . . LTDYDIRYYIYELLKALDYCHSQGIMHRDVKPHNVMIDHELRKLRLIDWGLAEFYHPGKE
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GGG...

TT



SGGGTTTT


TT


TT

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   111........120....... ..130.........140.........150.........160.........170.........180.......
 
   269270.........280...... ...290.........300.........310.........320.......
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Query Sequence  DPSKRVPIRWLSPETIVS. FLYTPQTDVFAFSILCWEVIENGAQPYPEMLVVQVHQKVGR. . . . . . . . . . . . . . . . . . . .
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Template Sequence  YNVRVASRYFKGPELLVDLQDYDYSLDMWSLGCMFAGMIFRKEPFFYGHDNHDQLVKIAKVLGTDGLNAYLNKYRIELDP
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S

S
GGG

TT

S

TT
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SS
TT



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   188.190.........200.........210.........220.........230.........240.........250.........260.......
 
   328.330.........340.........350.........360.....
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Query Sequence  . . . . . . . . . . . . . . . DDYRMPISQKAPAMLADVIKKCWIRDPQQRPTMSQVVQ
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Template Sequence  QLEALVGRHSRKPWLKFMNADNQHLVSPEAIDFLDKLLRYDHQERLTALEAMT
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GGGG

TTTGGG

TT

SSTTTS

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   268.270.........280.........290.........300.........310.........320
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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