Return to main results Retrieve Phyre Job Id

Job DescriptionQ20933
Confidence100.00%DateFri May 3 21:32:28 BST 2013
Rank75Aligned Residues239
% Identity29%Templatec3vw6B_
PDB info PDB header:transferase/transferase inhibitorChain: B: PDB Molecule:mitogen-activated protein kinase kinase kinase 5; PDBTitle: crystal structure of human apoptosis signal-regulating kinase 1 (ask1)2 with imidazopyridine inhibitor
Resolution2.40 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   107..110.........120.........130.........140.........150.........160.........170.........180......
Predicted Secondary structure 



















Query SS confidence 















































































Query Sequence  SWELNHADITMTKVLGEGAFGEVKLGTLKMGSTTVDVAIKVAKLEKVTKEQIKEIITEARLMRGFDHKNVVKCYGVAAID
Query Conservation                

 
 

 
             



                 
  

  
 
 


         
Alig confidence 
































..








........



























Template Conservation                

 
 

 

 
       .. 



 
  ........     
  

  
 




         
Template Sequence  EYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQV. . RIAIKEIPE. . . . . . . . QPLHEEIALHKHLKHKNIVQYLGSFSEN
Template Known Secondary structure 

B
TTSSB

SSSTTT

..
........
TT


TTB

T
Template Predicted Secondary structure 
















..
........








Template SS confidence 















































































   672.......680.........690.........700.... .....710... ......720.........730.........740.
 
   187..190.........200......... 210.........220.........230.........240........ .250.........260.
Predicted Secondary structure 










...





















..







Query SS confidence 






















. . .






































. .












Query Sequence  EPLLVVMELVPGGALDKYLQKNS. . . SVQWPEKLDIIAQVAAGLAYIHSKNIIHRDIAARNILYG. . KGVAKVSDFGLSR
Query Conservation      

 
    
 
        ...             
   
  

     
 


  
    ..    

 




 
Alig confidence 






















...






































..












Template Conservation      

 
    
 
   
                
       
  

     
      

                  
Template Sequence  GFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSK
Template Known Secondary structure  T

TT
BTT


TT
TT
S

SGGG
TTT




SS
Template Predicted Secondary structure 




















































Template SS confidence 















































































   748.750.........760.........770.........780.........790.........800.........810.........820.......
 
   262.......270.........280........ .290.........300.........310..... ....320.........330........
Predicted Secondary structure 



















..











.












Query SS confidence 


























. .


























.






















Query Sequence  VGTEYQMDPSKRVPIRWLSPETIVSFL. . YTPQTDVFAFSILCWEVIENGAQPYPE. MLVVQVHQKVGRDDYRMPISQKA
Query Conservation                  
 


      ..    






  
 

 
 
  
   .         
             
Alig confidence 


.........














..


















.






.






















Template Conservation     .........       

             













.
  

                          
Template Sequence  RLT. . . . . . . . . GTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMAT. GKPPFYELGEPQAAMFKVGMFKVHPEIPESM
Template Known Secondary structure 

.........

GGG


GGG
S.SS
TTGGG
ST





TTS
Template Predicted Secondary structure 


.........



















.





















Template SS confidence 















































































   828.830 .........840.........850.........860...... ...870.........880.........890.......
 
   339340.........350.........360.....
Predicted Secondary structure 







Query SS confidence 


























Query Sequence  PAMLADVIKKCWIRDPQQRPTMSQVVQ
Query Conservation     
  

  

  

  


   
  
Alig confidence 


























Template Conservation 
    


  

  

  


  


 
Template Sequence  SAEAKAFILKCFEPDPDKRACANDLLV
Template Known Secondary structure 
T
S
TTTS

T
Template Predicted Secondary structure 








Template SS confidence 


























   908.910.........920.........930....
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions
Phyre2 is part of Genome3D