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Job DescriptionQ20933
Confidence100.00%DateFri May 3 21:32:28 BST 2013
Rank78Aligned Residues255
% Identity28%Templatec3d4qA_
PDB info PDB header:transferaseChain: A: PDB Molecule:b-raf proto-oncogene serine/threonine-protein kinase; PDBTitle: pyrazole-based inhibitors of b-raf kinase
Resolution2.80 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   106...110.........120.........130.........140.........150.........160.........170.........180.....
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Query Sequence  QSWELNHADITMTKVLGEGAFGEVKLGTLKMGSTTVDVAIKVAKLEKVTKEQIKEIITEARLMRGFDHKNVVKCYGVAAI
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Template Sequence  DDWEIPDGQITVGQRIGSGSFGTVYKGKWHG. . . . . DVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMG. YST
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B

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   448.450.........460.........470........ .480.........490.........500.........510........ .520.
 
   186...190.........200.........210 .........220.........230.........240.........250 .........260...
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Query Sequence  DEPLLVVMELVPGGALDKYLQKNSS. VQWPEKLDIIAQVAAGLAYIHSKNIIHRDIAARNILYGKG. VAKVSDFGLSRVG
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Template Sequence  KPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLAT. .
Template Known Secondary structure  SSS


SS
BTS




TT
B
S

SGGGTTT


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   522.......530.........540.........550.........560.........570.........580.........590.........
 
   264.....270.........280........ .290.........300.........310.........320.........330... ...
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Query Sequence  TEYQMDPSKRVPIRWLSPETIVSFL. . . YTPQTDVFAFSILCWEVIENGAQPYPEMLVVQVHQKVGRDDYRMP. . . . ISQ
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Template Sequence  . . . . . . . VLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMT. GQLPYSNINNRDQIIFMVGRGYLSPDLSKVRS
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   600.........610.........620.........630......... 640.........650.........660.........670.
 
   337..340.........350.........360.........370......
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Query Sequence  KAPAMLADVIKKCWIRDPQQRPTMSQVVQMMYEITGKKDK
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Template Sequence  NCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPK
Template Known Secondary structure  TS
T
SSGGGS

T


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   684.....690.........700.........710.........720...
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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