Job Description Q9TYT3 Confidence 99.95% Date Sat Apr 13 13:01:24 BST 2013 Rank 17 Aligned Residues 128 % Identity 19% Template c3dxeC_ PDB info PDB header:protein binding Chain: C: PDB Molecule:amyloid beta a4 protein-binding family b member PDBTitle: crystal structure of the intracellular domain of human app2 (t668a mutant) in complex with fe65-ptb2 Resolution 2.00 Å Model Dimensions (Å) X: Y: Z:

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		13	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	S	S	G	V	S	L	S	A	T	Y	L	G	S	V	P	V	V	E	S	I	N	V	M	V	S	E	M	R	V	Q	V	V	S	E	C	I	Q	H	V	A	A	T	V	G	V	T	A	A	R	E	I	N	P	V	V	S	R	V	I	G	E	V	K	K	E	N	F	P	V	D	I	N	I	S	S	K	M	I	K
Query Conservation
Alig confidence																								.	.	.	.	.	.	.																							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																								.	.	.	.	.	.	.																							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		N	E	L	V	Q	K	F	Q	V	Y	Y	L	G	N	V	P	V	A	K	P	V	G	.	.	.	.	.	.	.	V	D	V	I	N	G	A	L	E	S	V	L	S	S	S	S	R	E	Q	W	T	P	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	S	H	V	S	V	A	P	A	T	L	T
Template Known Secondary structure				S	S														S		S			.	.	.	.	.	.	.														T			T	T	T	S			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.							S	S
Template Predicted Secondary structure																								.	.	.	.	.	.	.																							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		537	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.								.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580																			.	.	.	.	.	.	.	.	.	590	.
		93	.	.			.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170
Predicted Secondary structure					.	.
Query SS confidence					.	.
Query Sequence		I	I	K	.	.	Q	S	R	L	I	Q	R	H	P	F	S	F	F	S	F	G	A	Q	G	Q	K	G	T	D	T	E	L	M	F	G	Y	I	A	K	N	K	D	G	T	D	R	R	C	H	V	V	F	I	E	D	V	H	K	L	I	D	V	L	T	T	A	I	N	V	N	T	F	D	A	Q	A	N	A	S	T
Query Conservation					.	.
Alig confidence					.	.																							.	.	.	.												.														.	.	.										.
Template Conservation																													.	.	.	.												.														.	.	.										.
Template Sequence		I	L	H	Q	Q	T	E	A	V	L	G	E	C	R	V	R	F	L	S	F	L	A	V	G	R	D	V	.	.	.	.	H	T	F	A	F	I	M	A	A	G	P	.	A	S	F	C	C	H	M	F	W	C	E	P	N	.	.	.	A	A	S	L	S	E	A	V	Q	.	A	A	C	M	L	R	Y	Q	K	C	L
Template Known Secondary structure					T	T	T									G	G	G								S	S	T	.	.	.	.	T										T	.	T										S	S		.	.	.	S									.
Template Predicted Secondary structure																													.	.	.	.												.														.	.	.										.
Template SS confidence
		592	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.					.	620	.	.	.	.	.	.	.	.	.		630	.	.	.	.	.	.	.	.	.	640	.	.				.	.	.	.	.	.	.	650	.		.	.	.	.	.	.	.	.	660	.	.
		171	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		S	N	D	G
Query Conservation
Alig confidence
Template Conservation
Template Sequence		D	A	R	S
Template Known Secondary structure
Template Predicted Secondary structure
Template SS confidence
		663	.	.	.

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D