Job Description Q9TXI2 Confidence 100.00% Date Sat Apr 13 13:08:07 BST 2013 Rank 84 Aligned Residues 258 % Identity 29% Template c3v5qB_ PDB info PDB header:transferase/transferase inhibitor Chain: B: PDB Molecule:nt-3 growth factor receptor; PDBTitle: discovery of a selective trk inhibitor with efficacy in rodent cancer2 tumor models Resolution 2.20 Å

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		113	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.		.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.
Predicted Secondary structure																					.
Query SS confidence																					.
Query Sequence		W	E	I	E	H	S	Q	V	E	L	T	K	K	L	G	E	G	A	F	.	G	E	V	W	K	G	K	L	T	L	K	N	G	N	V	E	N	C	A	I	K	T	A	K	L	E	S	L	N	K	E	Q	I	K	E	I	M	R	E	A	R	L	M	R	N	L	D	H	P	N	V	V	K	F	Y	G	V	G	A	S
Query Conservation																					.
Alig confidence																					.										.	.	.															.	.
Template Conservation																															.	.	.															.	.
Template Sequence		Q	H	I	K	R	R	D	I	V	L	K	R	E	L	G	F	K	V	F	L	A	E	C	Y	N	L	S	P	T	.	.	.	K	D	K	M	L	V	A	V	K	A	L	K	D	P	.	.	T	L	A	A	R	K	D	F	Q	R	E	A	E	L	L	T	N	L	Q	H	E	H	I	V	K	F	Y	G	V	C	G	D
Template Known Secondary structure						G	G	G																		S			S	S	.	.	.	S	S											S		.	.																					T	T	B
Template Predicted Secondary structure																															.	.	.															.	.
Template SS confidence
		531	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.				560	.	.	.	.	.	.	.	.	.	570	.	.	.			.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.
		192	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.		.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.		.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																									.																																						.
Query SS confidence																									.																																						.
Query Sequence		Q	E	P	L	Y	V	I	M	E	L	A	D	C	G	A	L	D	S	Y	L	Q	K	N	.	P	N	L	V	P	D	K	K	M	E	M	I	Y	Q	A	A	C	G	I	S	Y	M	H	E	K	K	L	L	H	R	D	I	A	A	R	N	C	.	L	Y	G	G	G	Q	V	K	I	A	D	F	G	L	S	R	E	G
Query Conservation																									.																																						.
Alig confidence			.	.																					.																																						.
Template Conservation			.	.
Template Sequence		P	.	.	L	I	M	V	F	E	Y	M	K	H	G	D	L	N	K	F	L	R	A	H	G	P	E	L	G	L	S	Q	M	L	H	I	A	S	Q	I	A	S	G	M	V	Y	L	A	S	Q	H	F	V	H	R	D	L	A	T	R	N	C	L	V	G	A	N	L	L	V	K	I	G	D	F	G	M	D	V	Y	S
Template Known Secondary structure			.	.									T	T									T	T																										T	T				S			S	G	G	G					G	G	G												S	G
Template Predicted Secondary structure			.	.
Template SS confidence
		612			.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.
		270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	S	Y	V	M	D	L	T	K	K	V	P	I	R	W	L	A	P	E	T	L	K	A	G	I	Y	S	P	K	T	D	V	F	A	F	G	I	M	A	W	E	I	T	E	N	G	K	E	P	Y	P	D	M	R	V	A	D	V	V	G	K	V	R	N	G	Y	R	M	R	F	D	P	V	F	V	D	F	R	F	G
Query Conservation
Alig confidence											.	.	.																																																																		.	.
Template Conservation											.	.	.																																																																		.	.
Template Sequence		T	D	Y	Y	R	T	M	L	P	.	.	.	I	R	W	M	P	P	E	S	I	M	Y	R	K	F	T	T	E	S	D	V	W	S	F	G	V	I	L	W	E	I	F	T	Y	G	K	Q	P	W	F	Q	L	S	N	T	E	V	I	E	C	I	T	Q	G	R	V	L	E	R	P	R	V	C	P	K	E	.	.	V
Template Known Secondary structure		G	G		B				B		.	.	.	G	G	G																												T	T	T	S			T	T	T	T	S												T							T	T					.	.
Template Predicted Secondary structure											.	.	.																																																																		.	.
Template SS confidence
		707	.	.	710	.	.	.	.	.				.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780			.
		350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	Y	V	T	K	H	C	W	A	E	N	P	A	D	R	V	S	M	A	D	V	L	R	Y	L	Q	T	T	F	G	M	K	P
Query Conservation
Alig confidence
Template Conservation
Template Sequence		Y	D	V	M	L	G	C	W	Q	R	E	P	Q	Q	R	L	N	I	K	E	I	Y	K	I	L	H	A	L	G	K	A	T	P
Template Known Secondary structure											S	S	G	G	G	S																T
Template Predicted Secondary structure
Template SS confidence
		800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D