Job Description Q9TXI2 Confidence 100.00% Date Sat Apr 13 13:08:07 BST 2013 Rank 225 Aligned Residues 244 % Identity 21% Template c3kvwA_ PDB info PDB header:transferase Chain: A: PDB Molecule:dual specificity tyrosine-phosphorylation-regulated kinase PDBTitle: crystal structure of dual-specificity tyrosine phosphorylation2 regulated kinase 2 (dyrk2) in complex with an indirubin ligand Resolution 2.28 Å

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		119	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.							180	.	.	.	.	.	.	.	.	.	190	.	.
Predicted Secondary structure																																																															.	.	.	.	.	.
Query SS confidence																																																															.	.	.	.	.	.
Query Sequence		Q	V	E	L	T	K	K	L	G	E	G	A	F	G	E	V	W	K	G	K	L	T	L	K	N	G	N	V	E	N	C	A	I	K	T	A	K	L	E	S	L	N	K	E	Q	I	K	E	I	M	R	E	A	R	L	M	R	N	L	D	H	.	.	.	.	.	.	P	N	V	V	K	F	Y	G	V	G	A	S	Q
Query Conservation																																																															.	.	.	.	.	.
Alig confidence																								.	.	.													.	.	.																						.	.	.	.	.	.
Template Conservation																								.	.	.													.	.	.
Template Sequence		R	Y	E	V	L	K	V	I	G	K	G	S	F	G	Q	V	V	K	A	Y	D	H	.	.	.	K	V	H	Q	H	V	A	L	K	M	V	R	.	.	.	N	E	K	R	F	H	R	Q	A	A	E	E	I	R	I	L	E	H	L	R	K	Q	D	K	D	N	T	M	N	V	I	H	M	L	E	N	F	T	F	R
Template Known Secondary structure		T										S	S	S									T	.	.	.	T	T	T										.	.	.	S																				T	T		T	T	S		S		B										T
Template Predicted Secondary structure																								.	.	.													.	.	.
Template SS confidence
		148	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.				170	.	.	.	.	.	.	.	.	.	180	.				.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.
		193	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.			.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.				.	.	260	.	.	.	.	.	.	.
Predicted Secondary structure																										.	.																																										.	.	.
Query SS confidence																										.	.																																										.	.	.
Query Sequence		E	P	L	Y	V	I	M	E	L	A	D	C	G	A	L	D	S	Y	L	Q	K	N	P	N	.	.	L	V	P	D	K	K	M	E	M	I	Y	Q	A	A	C	G	I	S	Y	M	H	E	K	K	L	L	H	R	D	I	A	A	R	N	C	L	Y	G	G	G	Q	.	.	.	V	K	I	A	D	F	G	L	S	R
Query Conservation																										.	.																																										.	.	.
Alig confidence												.														.	.																																										.	.	.
Template Conservation												.
Template Sequence		N	H	I	C	M	T	F	E	L	L	.	S	M	N	L	Y	E	L	I	K	K	N	K	F	Q	G	F	S	L	P	L	V	R	K	F	A	H	S	I	L	Q	C	L	D	A	L	H	K	N	R	I	I	H	C	D	L	K	P	E	N	I	L	L	K	Q	Q	G	R	S	G	I	K	V	I	D	F	G	S	S	C
Template Known Secondary structure		T										.			B								T	T	T																										T				S			S	G	G	G				S	S	T	T	S									T	T
Template Predicted Secondary structure												.
Template SS confidence
		222	.	.	.	.	.	.	.	230	.		.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
		268	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																																																																										.	.	.	.	.	.	.	.
Query SS confidence																																																																										.	.	.	.	.	.	.	.
Query Sequence		E	G	I	S	Y	V	M	D	L	T	K	K	V	P	I	R	W	L	A	P	E	T	L	K	A	G	I	Y	S	P	K	T	D	V	F	A	F	G	I	M	A	W	E	I	T	E	N	G	K	E	P	Y	P	D	M	R	V	A	D	V	V	G	K	V	R	N	G	Y	R	M	R	F	.	.	.	.	.	.	.	.
Query Conservation																																																																										.	.	.	.	.	.	.	.
Alig confidence													.	.	.																																	.																										.	.	.	.	.	.	.	.
Template Conservation													.	.	.																																	.
Template Sequence		Y	E	H	Q	R	V	Y	T	I	Q	S	.	.	.	R	F	Y	R	A	P	E	V	I	L	G	A	R	Y	G	M	P	I	D	M	W	S	L	G	C	I	L	A	E	L	L	T	.	G	Y	P	L	L	P	G	E	D	E	G	D	Q	L	A	C	M	I	E	L	L	G	M	P	S	Q	K	L	L	D	A	S	K
Template Known Secondary structure			T	T									.	.	.	G	G	G								T	B				T																	.	S	S		S	S			S	S																						T	B	T
Template Predicted Secondary structure													.	.	.																																	.
Template SS confidence
		301	.	.	.	.	.	.	.	.	310	.				.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.		.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.
																																															340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	D	P	V	F	V	D	F	R	F	G	D	Y	V	T	K	H	C	W	A	E	N	P	A	D	R	V	S	M	A	D	V	L	R	Y
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		R	A	K	N	F	V	S	K	G	Y	P	R	Y	C	T	V	T	T	L	S	D	V	V	L	N	G	G	R	S	R	R	G	K	L	R	G	P	P	E	S	R	E	W	G	N	A	L	K	G	C	D	D	P	L	F	L	D	F	L	K	Q	C	L	E	W	D	P	A	V	R	M	T	P	G	Q	A	L	R	H
Template Known Secondary structure		T					B					B	T	T	S																T	T						S	T	T		S						T	T	T														T		S	S	T	T	T	S								T	S
Template Predicted Secondary structure
Template SS confidence
		378	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D