Job Description Q9TXI2 Confidence 100.00% Date Sat Apr 13 13:08:07 BST 2013 Rank 137 Aligned Residues 268 % Identity 22% Template c2r7bA_ PDB info PDB header:signaling protein, transferase Chain: A: PDB Molecule:phosphoinositide-dependent protein kinase 1; PDBTitle: crystal structure of the phosphoinositide-dependent kinase-2 1 (pdk-1)catalytic domain bound to a dibenzonaphthyridine3 inhibitor Resolution 2.70 Å

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		117	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.		160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.
Predicted Secondary structure																																													.
Query SS confidence																																													.
Query Sequence		H	S	Q	V	E	L	T	K	K	L	G	E	G	A	F	G	E	V	W	K	G	K	L	T	L	K	N	G	N	V	E	N	C	A	I	K	T	A	K	L	E	S	L	.	N	K	E	Q	I	K	E	I	M	R	E	A	R	L	M	R	N	L	D	H	P	N	V	V	K	F	Y	G	V	G	A	S	Q	E	P	L
Query Conservation																																													.
Alig confidence																										.	.	.																	.
Template Conservation																										.	.	.
Template Sequence		P	E	D	F	K	F	G	K	I	L	G	E	G	S	F	S	T	V	V	L	A	R	E	L	.	.	.	A	T	S	R	E	Y	A	I	K	I	L	E	K	R	H	I	I	K	E	N	K	V	P	Y	V	T	R	E	R	D	V	M	S	R	L	D	H	P	F	F	V	K	L	Y	F	T	F	Q	D	D	E	K	L
Template Known Secondary structure		G	G	G											S	S									T	.	.	.	T	T																	T	T														T				T	T	B										S	S
Template Predicted Secondary structure																										.	.	.
Template SS confidence
		79	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.				.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.
		196	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.		.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.
Predicted Secondary structure																																																										.
Query SS confidence																																																										.
Query Sequence		Y	V	I	M	E	L	A	D	C	G	A	L	D	S	Y	L	Q	K	N	P	N	L	V	P	D	K	K	M	E	M	I	Y	Q	A	A	C	G	I	S	Y	M	H	E	K	K	L	L	H	R	D	I	A	A	R	N	C	.	L	Y	G	G	G	Q	V	K	I	A	D	F	G	L	S	R	E	G	I	S	Y	V	M
Query Conservation																																																										.
Alig confidence																																																										.																			.	.	.	.	.
Template Conservation																																																																													.	.	.	.	.
Template Sequence		Y	F	G	L	S	Y	A	K	N	G	E	L	L	K	Y	I	R	K	I	G	S	F	D	E	T	C	T	R	F	Y	T	A	E	I	V	S	A	L	E	Y	L	H	G	K	G	I	I	H	R	D	L	K	P	E	N	I	L	L	N	E	D	M	H	I	Q	I	T	D	F	G	T	A	K	V	L	.	.	.	.	.
Template Known Secondary structure									T	T		B								S	S	S																							T	T								T	T	T					T	T	S								T	T					.	.	.	.	.
Template Predicted Secondary structure																																																																													.	.	.	.	.
Template SS confidence
		156	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230
		275	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	L	T	K	K	V	P	I	R	W	L	A	P	E	T	L	K	A	G	I	Y	S	P	K	T	D	V	F	A	F	G	I	M	A	W	E	I	T	E	N	G	K	E	P	Y	P	D	M	R	V	A	D	V	V	G	K	V	R	N	G	Y	R	M	R	F	D	P	V	F	V	D	F	R	F	G	D	Y	V	T	K
Query Conservation
Alig confidence		.	.	.																																					.																						.											.	.
Template Conservation		.	.	.																																					.																						.											.	.
Template Sequence		.	.	.	F	V	G	T	A	Q	Y	V	S	P	E	L	L	T	E	K	S	A	C	K	S	S	D	L	W	A	L	G	C	I	I	Y	Q	L	V	A	.	G	L	P	P	F	R	A	G	N	E	Y	L	I	F	Q	K	I	I	K	L	E	.	Y	D	F	P	E	K	F	F	P	K	.	.	A	R	D	L	V	E
Template Known Secondary structure		.	.	.					G	G	G								S	S																					.	S	S		S				S	S											T		.					S	S	S				.	.
Template Predicted Secondary structure		.	.	.																																					.																						.											.	.
Template SS confidence
					242	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.		.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.		.	300	.	.	.	.	.	.	.	.			.	310	.	.	.	.
		355	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		H	C	W	A	E	N	P	A	D	R	V	S	M	A	D	V	L	R	Y	L	Q	T	T	F	G	M	K	P	V	V	L	S	I	L	S	S	N	R	S	T	E	E	E	M	K	T	M	K	P	P	M	F	S
Query Conservation
Alig confidence																					.	.	.	.	.	.	.	.
Template Conservation																					.	.	.	.	.	.	.	.
Template Sequence		K	L	L	V	L	D	A	T	K	R	L	G	C	E	E	M	E	G	Y	.	.	.	.	.	.	.	.	G	P	L	K	A	H	P	F	F	E	S	V	T	W	E	N	L	H	Q	Q	T	P	P	K	L	T
Template Known Secondary structure		T	T	S		S	S	T	T	S	S	T	T	S	G	G	G	T	T		.	.	.	.	.	.	.	.						S	G	G	G	T	T			G	G	G	G	G	G	S
Template Predicted Secondary structure																					.	.	.	.	.	.	.	.
Template SS confidence
		315	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.									.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D