Job Description Q9TXI2 Confidence 100.00% Date Sat Apr 13 13:08:07 BST 2013 Rank 280 Aligned Residues 245 % Identity 22% Template c2pvmA_ PDB info PDB header:transferase Chain: A: PDB Molecule:casein kinase ii subunit alpha; PDBTitle: structure-based design of pyrazolo[1,5-a][1,3,5]triazine2 derivatives as potent inhibitors of protein kinase ck2 Resolution 2.00 Å

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		116	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.
Predicted Secondary structure																																																																																	.
Query SS confidence																																																																																	.
Query Sequence		E	H	S	Q	V	E	L	T	K	K	L	G	E	G	A	F	G	E	V	W	K	G	K	L	T	L	K	N	G	N	V	E	N	C	A	I	K	T	A	K	L	E	S	L	N	K	E	Q	I	K	E	I	M	R	E	A	R	L	M	R	N	L	D	H	P	N	V	V	K	F	Y	G	V	G	A	S	Q	E	P	.
Query Conservation																																																																																	.
Alig confidence																											.	.	.																.	.	.	.	.																																.
Template Conservation																											.	.	.																.	.	.	.	.
Template Sequence		E	Q	D	D	Y	E	V	V	R	K	V	G	R	G	K	Y	S	E	V	F	E	G	I	N	V	.	.	.	N	N	N	E	K	C	I	I	K	I	L	K	P	V	K	.	.	.	.	.	K	K	K	I	K	R	E	I	K	I	L	Q	N	L	G	G	P	N	I	V	K	L	L	D	I	V	R	D	Q	H	S	K
Template Known Secondary structure			G	G	G											S	S									T	.	.	.	T	T											S			.	.	.	.	.																	T	T	B										T	T	T
Template Predicted Secondary structure																											.	.	.																.	.	.	.	.
Template SS confidence
		35	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.				60	.	.	.	.	.	.	.	.	.	70	.	.	.	.						.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.
			195	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.			.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.
Predicted Secondary structure		.																																																										.	.
Query SS confidence		.																																																										.	.
Query Sequence		.	L	Y	V	I	M	E	L	A	D	C	G	A	L	D	S	Y	L	Q	K	N	P	N	L	V	P	D	K	K	M	E	M	I	Y	Q	A	A	C	G	I	S	Y	M	H	E	K	K	L	L	H	R	D	I	A	A	R	N	C	.	.	L	Y	G	G	G	Q	V	K	I	A	D	F	G	L	S	R	E	G	I	S
Query Conservation		.																																																										.	.
Alig confidence		.																				.	.	.																																				.	.
Template Conservation																						.	.	.
Template Sequence		T	P	S	L	I	F	E	Y	V	N	N	T	D	F	K	V	L	Y	P	T	.	.	.	L	T	D	Y	D	I	R	Y	Y	I	Y	E	L	L	K	A	L	D	Y	C	H	S	Q	G	I	M	H	R	D	V	K	P	H	N	V	M	I	D	H	E	L	R	K	L	R	L	I	D	W	G	L	A	E	F	Y	H	P
Template Known Secondary structure																			G	G	G	.	.	.																							T	T							S	G	G	G					T	T	T	T								T	T						T
Template Predicted Secondary structure																						.	.	.
Template SS confidence
		108	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.				.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.
		272	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.		.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330
Predicted Secondary structure																							.																																							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																							.																																							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		Y	V	M	D	L	T	K	K	V	P	I	R	W	L	A	P	E	T	L	K	A	.	G	I	Y	S	P	K	T	D	V	F	A	F	G	I	M	A	W	E	I	T	E	N	G	K	E	P	Y	P	D	M	R	V	A	D	V	V	G	K	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Conservation																							.																																							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																							.																																							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		G	K	E	Y	N	V	R	V	A	S	R	Y	F	K	G	P	E	L	L	V	D	L	Q	D	Y	D	Y	S	L	D	M	W	S	L	G	C	M	F	A	G	M	I	F	R	K	E	P	F	F	Y	G	H	D	N	H	D	Q	L	V	K	I	A	K	V	L	G	T	D	G	L	N	A	Y	L	N	K	Y	R	I	E
Template Known Secondary structure		T					S			S		G	G	G							T	T			S			T																	T		S	S	S	S			S	S																								T	T
Template Predicted Secondary structure
Template SS confidence
		185	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.
																		331	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	V	R	N	G	Y	R	M	R	F	D	P	V	F	V	D	F	R	F	G	D	Y	V	T	K	H	C	W	A	E	N	P	A	D	R	V	S	M	A	D	V	L	R	Y
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																	.	.
Template Conservation																																		.	.
Template Sequence		L	D	P	Q	L	E	A	L	V	G	R	H	S	R	K	P	W	L	K	F	M	N	A	D	N	Q	H	L	V	S	P	E	.	.	A	I	D	F	L	D	K	L	L	R	Y	D	H	Q	E	R	L	T	A	L	E	A	M	T	H
Template Known Secondary structure																		G	G	G	G			T	T	T	G	G	G					.	.							T	T			S	S	T	T	T	S									S
Template Predicted Secondary structure																																		.	.
Template SS confidence
		265	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.			.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D