Job Description Q9TXI2 Confidence 100.00% Date Sat Apr 13 13:08:07 BST 2013 Rank 4 Aligned Residues 370 % Identity 33% Template c2h8hA_ PDB info PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: src kinase in complex with a quinazoline inhibitor Resolution 2.20 Å Model Dimensions (Å) X:76.256 Y:63.959 Z:49.327

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		3	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.					.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.
Predicted Secondary structure																											.	.	.	.																																																			.
Query SS confidence																											.	.	.	.																																																			.
Query Sequence		D	K	D	I	H	S	E	H	W	Y	H	G	L	L	P	R	E	D	I	K	A	M	L	R	K	.	.	.	.	N	G	D	F	L	V	R	S	T	E	P	K	A	G	E	P	R	Q	Y	V	L	S	A	M	Q	S	E	E	L	E	D	A	G	V	K	H	Y	V	M	R	L	N	S	S	N	Q	I	F	L	E	.
Query Conservation																											.	.	.	.																																																			.
Alig confidence																											.	.	.	.																.	.	.																																	.
Template Conservation																																														.	.	.
Template Sequence		S	D	S	I	Q	A	E	E	W	Y	F	G	K	I	T	R	R	E	S	E	R	L	L	L	N	A	E	N	P	R	G	T	F	L	V	R	E	S	E	T	T	K	G	A	.	.	.	Y	C	L	S	V	S	D	F	D	N	A	K	G	L	N	V	K	H	Y	K	I	R	K	L	D	S	G	G	F	Y	I	T	S
Template Known Secondary structure		T	T	S	G	G	G	S	T	T	B			S											T		T	T			T	T								S	S	S	T	T		.	.	.										T	T	T										B		.			S						T
Template Predicted Secondary structure																																														.	.	.
Template SS confidence
		140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.				.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.
		78	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.									.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																																.	.	.	.	.	.	.	.
Query SS confidence																																.	.	.	.	.	.	.	.
Query Sequence		A	K	G	F	E	T	I	A	S	L	V	N	Y	Y	M	S	S	K	E	P	I	K	K	L	T	V	L	K	T	P	.	.	.	.	.	.	.	.	I	L	K	Q	P	W	E	I	E	H	S	Q	V	E	L	T	K	K	L	G	E	G	A	F	G	E	V	W	K	G	K	L	T	L	K	N	G	N	V	E	N	C
Query Conservation																																.	.	.	.	.	.	.	.
Alig confidence																																.	.	.	.	.	.	.	.																																		.	.	.	.
Template Conservation																																																																									.	.	.	.
Template Sequence		R	T	Q	F	N	S	L	Q	Q	L	V	A	Y	Y	S	K	H	A	D	G	L	C	H	R	L	T	T	V	C	P	T	S	K	P	Q	T	Q	G	L	A	K	D	A	W	E	I	P	R	E	S	L	R	L	E	V	K	L	G	Q	G	C	F	G	E	V	W	M	G	T	W	N	.	.	.	.	G	T	T	R	V
Template Known Secondary structure		T				S	S													T	T	S	S	S														S	S	S	S	T	T		S	B			G	G	G											S	S									T	.	.	.	.	T	T
Template Predicted Secondary structure																																																																									.	.	.	.
Template SS confidence
		217	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.					.	.	290	.	.
		150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210			.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.
Predicted Secondary structure																																																															.	.
Query SS confidence																																																															.	.
Query Sequence		A	I	K	T	A	K	L	E	S	L	N	K	E	Q	I	K	E	I	M	R	E	A	R	L	M	R	N	L	D	H	P	N	V	V	K	F	Y	G	V	G	A	S	Q	E	P	L	Y	V	I	M	E	L	A	D	C	G	A	L	D	S	Y	.	.	L	Q	K	N	P	N	L	V	P	D	K	K	M	E	M	I	Y
Query Conservation																																																															.	.
Alig confidence															.	.	.																										.																				.	.
Template Conservation															.	.	.																										.
Template Sequence		A	I	K	T	L	K	P	G	T	M	S	P	E	.	.	.	A	F	L	Q	E	A	Q	V	M	K	K	L	R	H	E	K	L	V	Q	L	Y	A	V	V	S	.	E	E	P	I	Y	I	V	T	E	Y	M	S	K	G	S	L	L	D	F	L	K	G	E	T	G	K	Y	L	R	L	P	Q	L	V	D	M	A	A
Template Known Secondary structure								T	T	S	S				.	.	.															T	T	B									.	S	S	S									T	T								S					T	T
Template Predicted Secondary structure															.	.	.																										.
Template SS confidence
		293	.	.	.	.	.	.	300	.	.	.	.	.				.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330		.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.
		228	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.		.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.			.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.
Predicted Secondary structure																										.																	.	.
Query SS confidence																										.																	.	.
Query Sequence		Q	A	A	C	G	I	S	Y	M	H	E	K	K	L	L	H	R	D	I	A	A	R	N	C	.	L	Y	G	G	G	Q	V	K	I	A	D	F	G	L	S	R	.	.	E	G	I	S	Y	V	M	D	L	T	K	K	V	P	I	R	W	L	A	P	E	T	L	K	A	G	I	Y	S	P	K	T	D	V	F	A	F
Query Conservation																										.																	.	.
Alig confidence																										.																	.	.
Template Conservation
Template Sequence		Q	I	A	S	G	M	A	Y	V	E	R	M	N	Y	V	H	R	D	L	R	A	A	N	I	L	V	G	E	N	L	V	C	K	V	A	D	F	G	L	A	R	L	I	E	D	N	E	Y	T	A	R	Q	G	A	K	F	P	I	K	W	T	A	P	E	A	A	L	Y	G	R	F	T	I	K	S	D	V	W	S	F
Template Known Secondary structure													T	T				S			S	G	G	G					G	G	G							T	T	S	T	T	T								T	T		S	T	T	S		G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		369	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.
		305	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	I	M	A	W	E	I	T	E	N	G	K	E	P	Y	P	D	M	R	V	A	D	V	V	G	K	V	R	N	G	Y	R	M	R	F	D	P	V	F	V	D	F	R	F	G	D	Y	V	T	K	H	C	W	A	E	N	P	A	D	R	V	S	M	A	D	V	L	R	Y	L	Q	T	T	F	G	M	K	P	V	V
Query Conservation
Alig confidence																																												.	.
Template Conservation																																												.	.
Template Sequence		G	I	L	L	T	E	L	T	T	K	G	R	V	P	Y	P	G	M	V	N	R	E	V	L	D	Q	V	E	R	G	Y	R	M	P	C	P	P	E	C	P	E	S	.	.	L	H	D	L	M	C	Q	C	W	R	K	E	P	E	E	R	P	T	F	E	Y	L	Q	A	F	L	E	D	Y	F	T	S	T	E	P	Q
Template Known Secondary structure									T	T	T	T			S	S	T	T												T	T							T	T					.	.									T		S	S	G	G	G	S												T	S	S				S
Template Predicted Secondary structure																																												.	.
Template SS confidence
		449	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490			.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.
		385
Predicted Secondary structure
Query SS confidence
Query Sequence		L
Query Conservation
Alig confidence
Template Conservation
Template Sequence		Q
Template Known Secondary structure
Template Predicted Secondary structure
Template SS confidence
		528

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D