Job Description Q9TXI2 Confidence 100.00% Date Sat Apr 13 13:08:07 BST 2013 Rank 117 Aligned Residues 248 % Identity 27% Template c1xkkA_ PDB info PDB header:transferase Chain: A: PDB Molecule:epidermal growth factor receptor; PDBTitle: egfr kinase domain complexed with a quinazoline inhibitor-2 gw572016 Resolution 2.40 Å

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		115	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	E	H	S	Q	V	E	L	T	K	K	L	G	E	G	A	F	G	E	V	W	K	G	K	L	T	L	K	N	G	N	V	E	N	C	A	I	K	T	A	K	L	E	S	L	N	K	E	Q	I	K	E	I	M	R	E	A	R	L	M	R	N	L	D	H	P	N	V	V	K	F	Y	G	V	G	A	S	Q	E	P
Query Conservation
Alig confidence																												.	.	.																.	.	.	.	.
Template Conservation																												.	.	.																.	.	.	.	.
Template Sequence		L	K	E	T	E	F	K	K	I	K	V	L	G	S	G	A	F	G	T	V	Y	K	G	L	W	I	.	.	.	P	V	K	I	P	V	A	I	K	E	L	R	E	K	A	.	.	.	.	.	N	K	E	I	L	D	E	A	Y	V	M	A	S	V	D	N	P	H	V	C	R	L	L	G	I	C	L	T	S	T	V
Template Known Secondary structure				T	T	T											S	S										.	.	.															T	.	.	.	.	.																	T	T	B									S	S	S
Template Predicted Secondary structure																												.	.	.																.	.	.	.	.
Template SS confidence
		707	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.				.	.	.	.	.	.	.	740	.	.	.	.	.	.	.						.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.
		195	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.		.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.
Predicted Secondary structure																																																											.
Query SS confidence																																																											.
Query Sequence		L	Y	V	I	M	E	L	A	D	C	G	A	L	D	S	Y	L	Q	K	N	P	N	L	V	P	D	K	K	M	E	M	I	Y	Q	A	A	C	G	I	S	Y	M	H	E	K	K	L	L	H	R	D	I	A	A	R	N	C	.	L	Y	G	G	G	Q	V	K	I	A	D	F	G	L	S	R	E	G	I	S	Y	V
Query Conservation																																																											.
Alig confidence																																																											.
Template Conservation
Template Sequence		Q	L	I	T	Q	L	M	P	F	G	C	L	L	D	Y	V	R	E	H	K	D	N	I	G	S	Q	Y	L	L	N	W	C	V	Q	I	A	K	G	M	N	Y	L	E	D	R	R	L	V	H	R	D	L	A	A	R	N	V	L	V	K	T	P	Q	H	V	K	I	T	D	F	G	L	A	K	L	L	G	A	E	E
Template Known Secondary structure									T	T		B								T	S	S	S																							T	T				S				G	G	G						T	T								S					T	T	T	T
Template Predicted Secondary structure
Template SS confidence
		787	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.
		274	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		M	D	L	T	K	K	V	P	I	R	W	L	A	P	E	T	L	K	A	G	I	Y	S	P	K	T	D	V	F	A	F	G	I	M	A	W	E	I	T	E	N	G	K	E	P	Y	P	D	M	R	V	A	D	V	V	G	K	V	R	N	G	Y	R	M	R	F	D	P	V	F	V	D	F	R	F	G	D	Y	V	T
Query Conservation
Alig confidence					.	.	.	.	.																																																																		.	.
Template Conservation					.	.	.	.	.																																																																		.	.
Template Sequence		K	V	P	.	.	.	.	.	I	K	W	M	A	L	E	S	I	L	H	R	I	Y	T	H	Q	S	D	V	W	S	Y	G	V	T	V	W	E	L	M	T	F	G	S	K	P	Y	D	G	I	P	A	S	E	I	S	S	I	L	E	K	G	E	R	L	P	Q	P	P	I	C	T	I	D	.	.	V	Y	M	I	M
Template Known Secondary structure					.	.	.	.	.	T	T	T	S																												T	T	S			T	T	T	T	S		G	G	G								T							T	T	B				.	.
Template Predicted Secondary structure					.	.	.	.	.																																																																		.	.
Template SS confidence
		867	.	.						870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.			.	.	.	.	.
		354	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		K	H	C	W	A	E	N	P	A	D	R	V	S	M	A	D	V	L	R	Y	L	Q	T	T
Query Conservation
Alig confidence
Template Conservation
Template Sequence		V	K	C	W	M	I	D	A	D	S	R	P	K	F	R	E	L	I	I	E	F	S	K	M
Template Known Secondary structure					T		S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		948	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D