|   |   |
6 | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | |
|
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|
. | . | . | . | . | . | . | . | 40 | . | . | |
|
. | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  | . | . | . | . |  |  |  |  |  |
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|
| . | . |
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
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|  |  |  |  |  |  |  |
|
|
| Query SS confidence |   |
|
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| . |
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| . |
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| Query Sequence |   |
Y | V | S | I | D | I | G | S | S | S | V | K | T | I | V | G | E | K | F | H | N | G | I | N | V | I | . |
. |
. |
. |
G | T | G | Q | T | Y | T | S | G | I | K | . |
. |
N | G | L | I | D | D | F | D | I | A | R | Q | A | I | K | D | T | I | K | K | A | S | I | A | S | G | V | D | I | K | E | V | F | L | K | L | P |
| Query Conservation |   |
  |
|
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|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|
| . | . | . | . |   |   |   |   |   |
|
|   |   |
|   | . | . |   |
|   |
|   |
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
| Alig confidence |   |
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| . | . |
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| . | . | . | . |
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| . | . |
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| . | . | . | . | . | . | . | . | . | . | . |
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| Template Conservation |   |
|
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|   |
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|   |   |   |
|
|   |   | . | . |   |   |   |   |   |   |
|
|   |
|   |   |   |   |
|   |   |
|
|   |
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|
| Template Sequence |   |
I | I | G | I | D | L | G | T | T | N | S | C | V | A | I | M | . |
. |
D | G | T | T | P | R | V | L | E | N | A | E | G | D | R | T | T | P | S | I | I | A | Y | T | Q | D | G | E | T | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | G | Q | P | A | K | R | Q | A | V | T | N | P | Q | N | T | L | F | A | I | K |
| Template Known Secondary structure |   |
|  |  |  |  |
|
| S | S |  |  |  |  |  |  |  | . | . |  | T | T |  |  |  |  |
|
|
| T | T | S |
| S | S |  |  |
|  |  |  |  |
| T | T | S |
|  |  | . | . | . | . | . | . | . | . | . | . | . |  | S |  |  |  |  | T | T | T | T | T |
| G | G | G |  |  |  |
| G | G |
| Template Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  | . | . |  |
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|  |  |  |  |  |
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|  |  |  |  |  |  |  |
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|  |  | . | . | . | . | . | . | . | . | . | . | . |  |
|  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
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|   |   |
4 | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | |
|
20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | |
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50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 |
|   |
|   |   |
80 | . | . | . | . | . | |
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. | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
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|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| Query SS confidence |   |
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
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| Query Sequence |   |
I | I | G | T | E | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
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. |
. |
. |
. |
Y | D | E | S | N | E | I | D | F | Y | E | D | T | E | I | N | G | S | H | I | E | K | V | L | E | G | I | R | E | K | N | D | V | Q | E | T | E | V | I | N | V | F | P | I | R | F | I | V | D | K |
| Query Conservation |   |
  |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |
|   |
| Alig confidence |   |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
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|
| . | . | . |
| Template Conservation |   |
  |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |   |   |   | . | . | . |
| Template Sequence |   |
R | L | I | G | R | R | F | Q | D | E | E | V | Q | R | D | V | S | I | M | P | F | K | I | I | A | A | D | N | G | D | A | W | V | E | V | K | G | Q | K | M | A | P | P | Q | I | S | A | E | V | L | K | K | M | K | K | T | A | E | D | Y | L | G | E | P | V | T | E | A | V | I | T | V | P | A | Y | F | N | . |
. |
. |
| Template Known Secondary structure |   |
G | T | T | T |
| B | S | S | S | T | T |  |  |  |  |  |  |  |
| S | S |
|  |  |  |
| T | T | S | B |  |  |  |  |  | T | T |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| S |
|
|
|  |  |  |  |  |  |
| T | T |
|
| . | . | . |
| Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
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|
|  |  |  |  |  |
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
| . | . | . |
| Template SS confidence |   |
|
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|   |   |
71 | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | |
|
|
|   |
|   |   |
136 | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | |
|
. | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . |
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |
| Query SS confidence |   |
|
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| . |
. |
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| Query Sequence |   |
E | N | E | V | S | D | P | K | E | L | I | A | R | H | S | L | K | V | E | A | G | V | I | A | I | Q | K | S | I | L | I | N | M | I | K | C | V | E | A | C | G | V | D | V | L | D | V | Y | S | D | A | Y | N | Y | G | S | I | L | T | A | T | . |
. |
E | K | E | L | G | A | C | V | I | D | I | G | E | D | V | T | Q |
| Query Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
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|   |
|   |   |
|   |   |
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|   |
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|   |   |   |   |   |   | . | . |   |   |   |   |   |
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| Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
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| . | . |
|
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| Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|   |   |
|   |   |
|
|   |   |
|
|   |   |   |   |   |
|
|   |
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
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|   |
|   |
|   |
|
|   |
|
| Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
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. |
. |
. |
. |
D | A | Q | R | Q | A | T | K | D | A | G | R | I | A | G | L | E | V | K | R | I | I | N | E | P | T | A | A | A | L | A | Y | G | L | D | K | G | T | G | N | R | T | I | A | V | Y | D | L | G | G | G | T | F | D |
| Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | T | S | S | S | S |  |  |  |  |  |  |  |  |  |
| S | S |
|  |  |
| Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
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|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
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|  |  |  |  |  |  |
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|  |  |  |
| Template SS confidence |   |
|
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|   |   |
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148 | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . |
|   |
|   |   |
214 | . | . | . | . | |
|
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. | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | |
|
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|
. | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| Query SS confidence |   |
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
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| . |
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. |
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| Query Sequence |   |
V | A | F | Y | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
R | G | E | L | V | D | A | D | S | I | E | M | A | G | R | D | I | T | D | D | I | A | Q | G | L | N | T | S | Y | . |
. |
. |
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. |
E | T | A | E | K | V | K | H | Q | Y | G | H | A | F | Y | D | S | A |
| Query Conservation |   |
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| Alig confidence |   |
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| Template Conservation |   |
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|   |   |   |   |   |   |   |
| Template Sequence |   |
I | S | I | I | E | I | D | E | V | D | G | E | K | T | F | E | V | L | A | T | N | G | D | T | H | L | G | G | E | D | F | D | S | R | L | I | N | Y | L | V | E | E | F | K | K | D | Q | G | I | D | L | R | N | D | P | L | A | M | Q | R | L | K | E | A | A | E | K | A | K | I | E | L | S | S | A | Q | Q | T | D | V |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |
| T | T | T | S |
|  |  |  |  |  |  |  |  |  |  | S | S |
| S | G | G | G | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
| S | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S | S | S |  |  |  |  |
| Template Predicted Secondary structure |   |
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| Template SS confidence |   |
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|   |   |
202 | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . |
|   |
|   |   |
266 | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | |
. | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . |
| Predicted Secondary structure |   |
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|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
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| Query SS confidence |   |
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| Query Sequence |   |
S | D | Q | D | I | F | T | V | E | Q | V | D | S | D | E | T | V | Q | Y | T | Q | K | D | L | S | D | F | I | E | A | R | V | E | E | I | F | F | E | V | F | D | V | L | Q | D | L | G | L | T | . |
K | V | N | G | G | F | I | V | T | G | G | S | A | N | L | L | G | V | K | E | L | L | S | D | M | V | S | E | K | V |
| Query Conservation |   |
  |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
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|   |   |   |   |   |   | . |   |   |   |   |   |
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|   |   |   |   |   |   |   |   |   |   |   |
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| Alig confidence |   |
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| Template Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |
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|   |   |
|   |   |   |   |   |   |
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|   |   |   |
|   |   |   |
|   |   |   |
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| Template Sequence |   |
N | L | P | Y | I | T | A | D | A | T | G | P | K | H | M | N | I | K | V | T | R | A | K | L | E | S | L | V | E | D | L | V | N | R | S | I | E | P | L | K | V | A | L | Q | D | A | G | L | S | V | S | D | I | D | D | V | I | L | V | G | G | Q | T | R | M | P | M | V | Q | K | K | V | A | E | F | F | G | K | E | P |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| S | T | T | G | G | G | T | S |  |  |  |  |  |  |  | T | T | T |
|
| T | T | T |
| S |  |  |  |  |  | S | G | G | G | G | S |  |  |  |  |  |  |  |  |  |  |  | S | S |
|
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| Template Predicted Secondary structure |   |
 |
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|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
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| Template SS confidence |   |
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|   |   |
282 | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . |
|   |
|   |   |
345 | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |
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| Query SS confidence |   |
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| Query Sequence |   |
R | I | H | T | P | S | Q | M | G | I | R | K | P | E | F | S | S | A | I | S | T | I | S | S | S | I | A | F | D | E | L | L | D | Y | V | T | I | N | Y | H | D | N | E | E | T | E | E | D | V | I | D | V | K | D | K | D | N | E | S | K | L | G | G | F | D | W | F | K | R | K | T | N | K | K | D | T | H | E | N | E |
| Query Conservation |   |
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
. | . | . | . | . | . | . |
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| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
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| Template Conservation |   |
. | . | . | . | . | . | . |   |   |   |   |   |   |
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|   |
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|   |   |
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|
| Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
R | K | D | V | N | P | D | E | A | V | A | I | G | A | A | V | Q | G | G | V | L | T | G | . |
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D | V | K | D | V | L | L | L | D | V | T | P | L | S | L | G | I | E | T | M | G | G | V | M | T | T | L | I | A | K | N | T | T | I | P |
| Template Known Secondary structure |   |
. | . | . | . | . | . | . | B |
| S | S |
| T | T | T |  |  |  |  |  |  |  |  |  |  | T | T | T | T | T | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | S |
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| S | B |
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|  |  |  |  |  | T | T | T |  |  |  |  |  |  |
| T | T | B |
| S | S |
| Template Predicted Secondary structure |   |
. | . | . | . | . | . | . |
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|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
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| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
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|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
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| Template SS confidence |   |
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|   |   |
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362 | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | |
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. | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . |
|   |
|   |   |
425 | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
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|  |  |  |  |  |  |  |  |
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|  |
| Query SS confidence |   |
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| Query Sequence |   |
V | E | S | T | D | E | E | I | Y | Q | S | E | D | N | H | Q | E | H | K | Q | N | H | E | H | V | Q | D | K | D | K | D | K | E | E |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
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| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
T | K | H | S | Q | V | F | S | T | A | E | D | N | Q | S | A | V | T | I | H | V | L | Q | G | E | R | K | R | A | A | D | N | K | S |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |
|
| S | S | T | T |
|
|  |  |  |  |  |  |  |  | S | S |
| S | B | G | G | G | S |  |  |
| Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |
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| Template SS confidence |   |
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|   |   |
420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . |
|   |