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Job DescriptionP47768
Confidence100.00%DateTue Jul 17 17:05:10 BST 2012
Rank5Aligned Residues998
% Identity26%Templatec3h0gN_
PDB info PDB header:transcriptionChain: N: PDB Molecule:dna-directed rna polymerase ii subunit rpb2; PDBTitle: rna polymerase ii from schizosaccharomyces pombe
Resolution3.65 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   15....20.........30.........40.........50.........60.........70.... .....80....
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Query Sequence  RNYARISEVLELPNLIEIQTKSYEWFLREGLIEMFRDISPIEDFTGNLSLEFVDYRLGEP. . . . . . . . . . KYDLEESKNR
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Template Sequence  DCWTVISSFFEETSLARQQLFSFDEFVQNTMQEIVDDDSTLT. . . . . . . INFGQIYLSRPTMTEADGSTTTMFPQEARLR
Template Known Secondary structure  T
TT
SSSSSSSSSTTTTSSTT



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B
TTS
B



TTTTTTT
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   16...20.........30.........40.........50....... ..60.........70.........80........
 
   85....90.........100.........110.........120.. .......130.........140
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Query Sequence  DATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMTDT. . . . . . . . . . . . . . . . . . . . . . . . GTFVINGAERVIVSQLVR
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Template Sequence  NLTYSSPLYVDMRKEDEEP. . . . . SKVFIGKIPIMLRSTFCILNGVSDSELYDLNECPYDQGGYFIINGSEKVIIAQERS
Template Known Secondary structure 






SS
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SSSTTSSSSS

TT

TT




B
GGGS
B


B



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   108.110.........120...... ...130.........140.........150.........160.........170.........180..
 
   141........150.........160.. .......170.... .....180........ .190.........200.......
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Query Sequence  SPSVYFNEKIDKNGRENYDATI. . IPNRGAWLEYET. . . . . . . . . . DAKDVVYVRIDRTR. KLPLTVLLRALGFSSDQEI
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Template Sequence  AANIVQVFKKAAPSPIAYVAEIRSALERGSRLISSMQIKLMARNTENSGQTIRATLPYIRSDIPIVIVFRALGVVPDRDI
Template Known Secondary structure 

S








SSS











SSS













TTS
S






TTS
S


STTTT

STT
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   204.....210.........220.........230.........240.........250.........260.........270.........280...
 
   208.210.........220.........230.........240.........250.........260 .........270.........280.....
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Query Sequence  VDLLGDNEYLRNTLEKDGTENTEQALLEIYERLRPGEPPTVENAKSLLYSRFF. . DPKRYDLASVGRYKTNKKLHLKHRL
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Template Sequence  LEHICYDPNDFQMLE. . . . . . . . . . . MMKPCIEEAFVIQDKDIALDYIGKRGSTTGVTREKRLRYAHDILQKELLPHITT
Template Known Secondary structure 

SS

...........TTTSS

SSTT


SSS



TTTSS
SS

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   284.....290........ .300.........310.........320.........330.........340.........350..
 
   286...290.........300.........310.........320.........330.........340.........350.........360.....
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Query Sequence  FNQKLAEPIVNTETGEIVVEEGTVLDRRKIDEIMDVLESNANSEVFELHGSVIDEPVEIQSIKVYVPNDDEGRTTTVIGN
Query Conservation                                      
                                           
Template Conservation  ................................................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  ................................................................................
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   366...370.........380.........390.........400.........410.........420.........430....... ..440...
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Query Sequence  AFPDSEVKCITPADIIASMSYFFNLLSGIGYTDDIDHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQ. . DTESIT
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Template Sequence  . . . MEGFETRKAFFLGYMIHRMLLCALERREPDDRDHFGKKRLDLAGPLLASLFRMLFRKMTRDVYKYMQKCVETNREFN
Template Known Secondary structure  ...SSS

SSTTSS



TT
SSS




TT

S

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   353......360.........370.........380.........390.........400.........410.........420.........
 
   444.....450.........460. ........470.........480.........490.........500.........510
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Query Sequence  PQQLINIRPVIASIKEFF. . . . . . . . . . . . . GSSQLSQFMDQANPLAELTHKRRLSALGPGGLTRERAQMEVRDVHYSHY
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Template Sequence  LTLAVKSNIITNGLRYSLATGNWGDQKRSMVNRVGVSQVLNRYTFASTLSHLRRTN. . . . TPIGRDGKLAKPRQLHNTHW
Template Known Secondary structure 
TTSS
STTTSSSS
SSTTSS

S



S

B


SSTTBB
....
S

SS

SSSSSS

GGGT
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   430.........440.........450.........460.........470.........480..... ....490.........500.....
 
   511........520.........530.........540.........550.........560.........570.........580. ......
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Query Sequence  GRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVDLDTHAITDQIDYLTADEEDSYVVAQANSKLD. . . ENGRFM
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Template Sequence  GMVCPAETPEGQACGLVKNLSLMSYVS. VGSPSAPIIEFLEEWGLETLED. YNPSASPNATKVFVNGVWLGVHRDPAHLT
Template Known Secondary structure  TT


S


SSSSTTTS
B

SS

B
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SSSSS



S
.

SSSSSSS



STT





S
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   506...510.........520.........530.. .......540.........550.... .....560.........570.........580...
 
   588.590.........600.........610.........620...... ...630.........640 .........650.........660
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Query Sequence  DDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATACIP. FLENDDSNRALMGA. NMQRQAVPLMNPEAPFVGTG. . . . .
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Template Sequence  ETLRSLRRRLDISAEVSIVRDIREKELRLFTDAGRICRPLFIVDNNPNSERRGELCIRKEHIQQLIEDKDRYDIDPEQRF
Template Known Secondary structure  TTTSS
TT





TTT






SS

B




SS
SSSS


SS
T


S
TT


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   584.....590.........600.........610.........620.........630.........640.........650.........660...
 
   661........670........ .680.........690.......
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Query Sequence  . . . . . . . . . . MEHVAARDSGAAITAKHR. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . GRVEHVESNEILVRRLVEE
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Template Conservation            

 
   
     

                                       
  

     
   
 
Template Sequence  GWTALVSSGLIEYLDAEEEETVMIAMSPEDLEASRQMQAGYEVKEELDPAQRVKPAPNPHVHAWTHCEIHPAMILGILAS
Template Known Secondary structure  SSTTTTTTTS

TTTGGG

S
TT





SS

SS




S

S

S
S
S
GGGSS
SSST
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   664.....670.........680.........690.........700.........710.........720.........730.........740...
 
   698.700 .........710......... 720.........730.........740......... 750.........760.........
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Query Sequence  NGV. . . EHEGELDRYPLAKFKRSNS. . GTCYNQRPIVAVGDVVEYNEILADGPSMEL. . . GEMALGRNVVVGFMTWDGYN
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Template Sequence  IIPFPDHNQSPRNTYQSAMGKQAMGVYLTNYQVRMDTMANILYYPQKPLATTRSMEYLKFRELPAGQNAIVAILCYSGYN
Template Known Secondary structure  TSSSSTTS
STT

S


TTTTTS

SSSS



SSB
TTSTTTT
TTS
S


B


SSSS
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   744.....750.........760.........770.........780.........790.........800.........810.........820...
 
   770.........780.........790.........800.... .....810.... .....820.........830.........840....
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Query Sequence  YEDAVIMSERLVKDDVYTSIHIEEYESEARDTKLG. PEEITRDIPN. . . . VSESALKNLDDRGIVYIGAEVKDGDILVGK
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Template Sequence  QEDSIIMNQASIDRGLFRSIFYRTYTDQEKKIGMTVMEEFERPVRSTTLRMKHGTYDKLEDDGLIAPGTRVSGEDIIIGK
Template Known Secondary structure 
SS
TTTTT





SSS








TTS




S

GGG

TTSS

TT



TT





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   824.....830.........840.........850.........860.........870.........880.........890.........900...
 
   845....850.........860.........870.........880.........890.........900.........910.........920....
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Query Sequence  VTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPHGAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIVQKRKIHVGDK
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Template Sequence  TAPIQLH. . . . . . . . . . . . . . . . . . AKRDVSTPLRSTESGIVDQVMVTTNQEG. . . . . . . . LKFVKVRMRSTRIPQIGDK
Template Known Secondary structure 






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TT






SSS........S


B


TT
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   904.....910 .........920.........930........ .940.........950.......
 
   925....930.........940.........950.........960.........970.........980.........990.........1000....
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Query Sequence  MCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPLGVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTI
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Template Sequence  FASRHGQKGTIGMTYRHEDMPFSAQGIVPDIIINPHAIPSRMTVAHLVECQLSKVSALSGFEGDATPFTDVTVEAVSKLL
Template Known Secondary structure 
TT



TTTS

BTTTB

S

GGGSTTS

SSSS



B

SS
S

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   969970.........980.........990.........1000.........1010.........1020.........1030.........1040........
 
   1005....1010.........1020.........1030.........1040.........1050.........1060.........1070.........1080....
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Query Sequence  EEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLKLAHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALE
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Template Sequence  RSHGFQSRGFEVMYHGHTGRKLVAQVFLGPTYYQRLKHLVDDKIHARARGPVQILTRQPVEGRSRDGGLRFGEMERDCQI
Template Known Secondary structure  TTTS
TTS
B

B
SSS

B
SS
B



S

STTT



SS

B
SSS
SB

SSTT






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   10491050.........1060.........1070.........1080.........1090.........1100.........1110.........1120........
 
   1085....1090.........1100. ....... .1110.........1120.........1130.........1140........
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Query Sequence  AYGAAYTLQEILTYKSD. . . . DTVGRVK. . . . . . . . . . . . TYEAIVKGENISRPSVPESFRVLMKELQSLGLDVKVMDEQ
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Template Sequence  SHGCSSVLRERLFDCSDAYRVIVCDICGLIAIASYKKDSYECRSCQNRTRFSQVYLPYAAKLLFQELMSMNIAPRLFTKN
Template Known Secondary structure  T
TTTT

SSS






SSS




TTT

SS


TTT






ST
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   11291130.........1140.........1150.........1160.........1170.........1180.........1190.........1200........
 
   11491150
Predicted Secondary structure 

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Query Sequence  DN
Query Conservation    
Alig confidence 

Template Conservation    
Template Sequence  HK
Template Known Secondary structure  T
Template Predicted Secondary structure 

Template SS confidence 

   12091210
 
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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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