Job Description O06446 Confidence 99.88% Date Tue Jul 17 17:05:02 BST 2012 Rank 25 Aligned Residues 458 % Identity 14% Template c3tmiA_ PDB info PDB header:hydrolase/rna Chain: A: PDB Molecule:atp-dependent rna helicase ddx58; PDBTitle: structural basis for rna recognition and activation of rig-i Resolution 2.90 Å

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		84	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.			.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.						.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.
Predicted Secondary structure																					.	.																									.	.	.	.	.
Query SS confidence																					.	.																									.	.	.	.	.
Query Sequence		N	M	T	P	Y	K	V	Q	I	M	G	G	I	A	I	H	K	G	D	.	.	I	A	E	M	R	T	G	E	G	K	T	L	T	A	T	M	P	T	Y	L	N	A	L	A	.	.	.	.	.	G	R	G	V	H	V	I	T	V	N	E	Y	L	S	S	V	Q	S	E	E	M	A	E	L	Y	N	F	L	G	L
Query Conservation																					.	.																									.	.	.	.	.
Alig confidence																					.	.																									.	.	.	.	.
Template Conservation
Template Sequence		P	F	K	P	R	N	Y	Q	L	E	L	A	L	P	A	M	K	G	K	N	T	I	I	C	A	P	T	G	C	G	K	T	F	V	S	L	L	I	C	E	H	H	L	K	K	F	P	Q	G	Q	K	G	K	V	V	F	F	A	N	Q	I	P	V	Y	E	Q	Q	K	S	V	F	S	K	Y	F	E	R	H	G	Y
Template Known Secondary structure												T	T					T	T									T	T	S																T	S		T	T										S	S																T	T	T	T
Template Predicted Secondary structure
Template SS confidence
		240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.
		157	.	.	160	.	.	.	.	.	.			.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.
Predicted Secondary structure												.	.
Query SS confidence												.	.
Query Sequence		T	V	G	L	N	L	N	S	K	T	.	.	T	E	E	K	R	E	A	Y	A	Q	D	I	T	Y	S	T	N	N	E	L	G	F	D	Y	L	R	D	N	M	V	N	Y	S	E	D	R	V	M	R	P	L	H	F	A	I	I	D	E	V	D	S	I	L	I	D	E	A	R	T	P	L	I	I	S	G	E	A	E
Query Conservation												.	.
Alig confidence												.	.																					.	.	.	.	.	.																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																		.	.	.	.	.	.																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		R	V	T	G	I	S	G	A	T	A	E	N	V	P	V	E	Q	I	V	E	N	N	D	I	I	I	L	T	P	Q	I	L	.	.	.	.	.	.	V	N	N	L	K	K	G	T	I	P	S	L	S	I	F	T	L	M	I	F	D	E	C	H	N	T	S	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure								T	T	T		S	S	S								T		S										.	.	.	.	.	.						T	T	S	S			G	G	G		S						T	G	G	G	S	S	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																																		.	.	.	.	.	.																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.							.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.
		235	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		K	S	T	S	L	Y	T	Q	A	N	V	F	A	K	M	L	K	Q	D	E	D	Y	K	Y	D	E	K	T	K	A	V	H	L	T	E	Q	G	A	D	K	A	E	R	M	F	K	V	E	N	L	Y	D	V	Q	N	V	D	V	I	S	H	I	N	T	A	L	R	A	H	V	T	L	Q	R	D	V	D	Y	M	V
Query Conservation
Alig confidence		.																	.	.																		.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation		.																	.	.																		.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	K	Q	H	P	Y	N	M	I	M	F	N	Y	L	D	Q	K	.	.	L	G	G	S	S	G	P	L	P	Q	V	I	G	L	T	A	S	.	.	.	.	.	.	.	.	.	.	.	.	.	V	G	V	G	D	A	K	N	T	D	E	A	L	D	Y	I	C	K	L	C	A	S	L	D	A	S	V	I	A	T	V
Template Known Secondary structure		.	S	S	S													T	.	.	T	S	S			S										S		.	.	.	.	.	.	.	.	.	.	.	.	.				T	T		S	S															T	T		S
Template Predicted Secondary structure		.																	.	.																		.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
			379	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.			.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.														.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.
		315	.	.												.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.
Predicted Secondary structure					.	.	.	.	.	.	.	.	.	.	.
Query SS confidence					.	.	.	.	.	.	.	.	.	.	.
Query Sequence		V	D	G	.	.	.	.	.	.	.	.	.	.	.	E	V	L	I	V	D	Q	F	T	G	R	T	M	P	G	R	R	F	S	E	G	L	H	Q	A	I	E	A	K	E	G	V	Q	I	Q	N	E	S	K	T	M	A	S	I	T	F	Q	N	Y	F	R	M	Y	N	K	L	A	G	M	T	G	T	A	K	T	E
Query Conservation					.	.	.	.	.	.	.	.	.	.	.
Alig confidence					.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		K	H	N	L	E	E	L	E	Q	V	V	Y	K	P	Q	K	F	F	R	K	V	E	S	R	I	S	D	K	F	K	Y	I	I	A	Q	L	M	R	D	T	E	S	L	A	K	R	I	C	K	D	L	E	N	F	G	T	Q	K	Y	E	Q	W	I	V	T	V	Q	K	A	C	M	V	D	K	D	E	E	S	R	I
Template Known Secondary structure			S							T	T	S														S			T																					S							S													G	G	G				S	S		T
Template Predicted Secondary structure
Template SS confidence
		443	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.
		384	.	.	.	.	.	390	.	.	.																																								.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.
Predicted Secondary structure												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		E	E	E	F	R	N	I	Y	N	M	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	T	V	T	Q	I	P	T	N	K	P	V	Q	R	N	D	K	S	D	L	I	Y	I	S	Q	K	G	K	F	D	A	V
Query Conservation												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		C	K	A	L	F	L	Y	T	S	H	L	R	K	Y	N	D	A	L	I	I	S	E	H	A	R	M	K	D	A	L	D	Y	L	K	D	F	F	S	N	V	R	A	A	G	F	D	E	I	E	Q	D	L	T	Q	R	F	E	E	K	L	Q	E	L	E	S	V	S	R	D	P	S	N	E	N	P	K	L	E	D	L
Template Known Secondary structure																									S																	T	T	T											T	T	S	S	S							S	S	S	S		S	S				T	T
Template Predicted Secondary structure
Template SS confidence
		535	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.
		425	.	.	.	.	430	.	.	.	.	.	.			.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.													.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.		.	.	.	.	.
Predicted Secondary structure														.	.																							.	.	.	.	.	.	.	.	.	.	.	.																											.
Query SS confidence														.	.																							.	.	.	.	.	.	.	.	.	.	.	.																											.
Query Sequence		V	E	D	V	V	E	K	H	K	A	G	Q	.	.	P	V	L	L	G	T	V	A	V	E	T	S	E	Y	I	S	N	L	L	K	K	R	.	.	.	.	.	.	.	.	.	.	.	.	G	I	R	H	D	V	L	N	A	K	N	H	E	R	E	A	E	I	V	A	G	A	G	Q	K	G	.	A	V	T	I	A
Query Conservation														.	.																							.	.	.	.	.	.	.	.	.	.	.	.																											.
Alig confidence														.	.																							.	.	.	.	.	.	.	.	.	.	.	.																											.
Template Conservation
Template Sequence		C	F	I	L	Q	E	E	Y	H	L	N	P	E	T	I	T	I	L	F	V	K	T	R	A	L	V	D	A	L	K	N	W	I	E	G	N	P	K	L	S	F	L	K	P	G	I	L	T	G	R	G	K	T	N	Q	N	T	G	M	T	L	P	A	Q	K	C	I	L	D	A	F	K	A	D	H	N	I	L	I	A
Template Known Secondary structure													T	T								S														S	S	T	T			S									S				S	S	S														T	S					S
Template Predicted Secondary structure
Template SS confidence
		615	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.
		490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.		.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.
Predicted Secondary structure																								.
Query SS confidence																								.
Query Sequence		T	N	M	A	G	R	G	T	D	I	K	L	G	E	G	V	E	E	L	G	G	L	.	A	V	I	G	T	E	R	H	E	S	R	R	I	D	D	Q	L	R	G	R	S	G	R	Q	G	D	K	G	D	S	R	F	Y	L	S	L	Q	D	E	L	M	I	R	F	G	S	E	R	L	Q	K	M	M	S	R	L	G
Query Conservation																								.
Alig confidence													.	.	.	.	.	.	.	.	.			.																								.	.	.
Template Conservation													.	.	.	.	.	.	.	.	.																											.	.	.
Template Sequence		T	S	V	A	D	E	G	I	D	I	A	.	.	.	.	.	.	.	.	.	Q	C	N	L	V	I	L	Y	E	Y	V	G	N	V	I	K	M	I	Q	T	R	G	R	G	R	A	.	.	.	R	G	S	K	C	F	L	L	T	S	N	A	G	V	I	E	K	E	Q	I	N	M	Y	K	E	K	M	M	N	D	S
Template Known Secondary structure							S						.	.	.	.	.	.	.	.	.			S						S												T	T	S	S		S	.	.	.	S									S	S	S
Template Predicted Secondary structure													.	.	.	.	.	.	.	.	.																											.	.	.
Template SS confidence
		697	.	.	700	.	.	.	.	.	.	.										.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.				.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.
		569	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590
Predicted Secondary structure
Query SS confidence
Query Sequence		L	D	D	S	T	P	I	E	S	K	M	V	S	R	A	V	E	S	A	Q	K	R
Query Conservation
Alig confidence
Template Conservation
Template Sequence		I	L	R	L	Q	T	W	D	E	A	V	F	R	E	K	I	L	H	I	Q	T	H
Template Known Secondary structure							T	S		T	T	T
Template Predicted Secondary structure
Template SS confidence
		765	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.