|   |   |
75 | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | |
|
. | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | |
|
|
. | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
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|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
| . | . |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . |
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
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| . |
. |
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| . |
. |
. |
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| Query Sequence |   |
V | R | E | G | S | K | R | V | F | N | M | T | P | Y | K | V | Q | I | M | G | G | I | A | I | H | K | G | D | . |
. |
I | A | E | M | R | T | G | E | G | K | T | L | T | A | T | M | P | T | Y | L | N | A | L | A | . |
. |
. |
G | R | G | V | H | V | I | T | V | N | E | Y | L | S | S | V | Q | S | E | E | M | A | E |
| Query Conservation |   |
|
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|   |   |
|   |
|
|   |   |
|   |   |
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|
|   |   |   |
|   |   |
|   | . | . |
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|   |
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|   |   |
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|   |
|   |
|
|   | . | . | . |
|   |   |
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|   |
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|   |
|
|   |
|   |   |   |   |
| Alig confidence |   |
|
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| . | . |
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| . | . | . |
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| Template Conservation |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|
|   |   |   |   |
|
|
|   |
|
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|
|
|   |   |   |
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |
| Template Sequence |   |
L | L | R | A | I | V | D | C | G | F | E | H | P | S | E | V | Q | H | E | C | I | P | Q | A | I | L | G | M | D | V | L | C | Q | A | K | S | G | M | G | K | T | A | V | F | V | L | A | T | L | Q | Q | L | E | P | V | T | G | Q | V | S | V | L | V | M | C | H | T | R | E | L | A | F | Q | I | S | K | E | Y | E | R |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  | T | T |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |
|
| S | S | T | T |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| T | T |
|
|
|  |  |  |  |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
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|
|  |  |  |  |  |  |  |  |  |  |  |
|
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|  |  |  |  |
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|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
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|   |   |
56 | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . |
|   |
|   |   |
150 | . | . | . | . | |
. | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | |
|
|
. | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  | . |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  | . | . | . |
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
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|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
| . |
|
|
|
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|
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|
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|
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|
|
|
|
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|
| . |
. |
. |
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|
| Query Sequence |   |
L | Y | N | F | L | . |
G | L | T | V | G | L | N | L | N | S | K | T | T | E | E | K | R | E | A | . |
. |
. |
Y | A | Q | D | I | T | Y | S | T | N | N | E | L | G | F | D | Y | L | R | D | N | M | V | N | Y | S | E | D | R | V | M | R | P | L | H | F | A | I | I | D | E | V | D | S | I | L | I | D | E | A | R | T |
| Query Conservation |   |
|
|   |   |
| . |
|
|
|
|   |   |
|   |   |   |   |   |   |   |
|
|   |   |   | . | . | . |
|   |   |
|
|   |
|
|
|   |   |
|
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|
|   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |
|
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|
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|
|
| Alig confidence |   |
|
|
|
|
| . |
|
|
|
|
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|
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|
|
|
|
|
|
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|
| . | . | . |
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|
|
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|
|
| . |
|
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|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |
| Template Sequence |   |
F | S | K | Y | M | P | N | V | K | V | A | V | F | F | G | G | L | S | I | K | K | D | E | E | V | L | K | K | N | C | P | H | I | V | V | G | T | P | G | R | I | . |
L | A | L | A | R | N | K | S | L | N | . |
. |
. |
. |
. |
. |
L | K | H | I | K | H | F | I | L | D | E | A | D | K | M | L | . |
. |
. |
. |
. |
. |
| Template Known Secondary structure |   |
 | T | T | T |
| T | T |
|
|  |  |  |  |
| T | T | S |
|  |  |  |  |  |  |  |  |  |  | S |
|
| S |  |  |  |  |
|  |  |  |  | . |  |  |  |  |  | T | T | S | S |
| . | . | . | . | . | . |
| T | T |
|
|  |  |  |  |  | S |  |  |  |  |  | . | . | . | . | . | . |
| Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |
|
|  |  |  |  | . |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . |
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  | . | . | . | . | . | . |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
|   |   |
136 | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | |
. | . | . | 180 | . | . | . | . | . | . | |
|
|
|
|
|
. | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | |
|
|
|
|
|
|   |
|   |   |
226 | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . |
| Predicted Secondary structure |   |
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
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|
|  |  |  |
|
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|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |
|
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|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
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|
| Query Sequence |   |
P | L | I | I | S | G | E | A | E | K | S | T | S | L | Y | T | Q | A | N | V | F | A | K | M | L | K | Q | D | E | D | Y | K | Y | D | E | K | T | K | A | V | H | L | T | E | Q | G | A | D | K | A | E | R | M | F | K | V | E | N | L | Y | D | V | Q | N | V | D | V | I | S | H | I | N | T | A | L | R | A | H | V | T |
| Query Conservation |   |
|
|
|
|
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|   |   |
|   |   |   |   |
|
|   |   |
|   |   |   |   |   |
|   |
|
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |
|   |   |
|
| Alig confidence |   |
. | . | . | . | . | . | . | . | . | . |
|
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| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Template Conservation |   |
. | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | Q | L | D | M | R | R | D | V | Q | E | I | F | R | M | T | P | H | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
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. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
| Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | S | S |  |  |  |  |  |  |  |  |  |  |  |  | T | S |
| S | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . |
|
|
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|
|
|  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| Template SS confidence |   |
|
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|   |   |
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|
203 | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | |
|
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|   |
|   |   |
306 | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |
|
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|
|  |  |  |  |
|
|
|  |  |  |  |
|
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|  |  |  |  |  |  |  |  |  |  |  |  |  |
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|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
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|
|  |  |  |  |  |  |
| Query SS confidence |   |
|
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| Query Sequence |   |
L | Q | R | D | V | D | Y | M | V | V | D | G | E | V | L | I | V | D | Q | F | T | G | R | T | M | P | G | R | R | F | S | E | G | L | H | Q | A | I | E | A | K | E | G | V | Q | I | Q | N | E | S | K | T | M | A | S | I | T | F | Q | N | Y | F | R | M | Y | N | K | L | A | G | M | T | G | T | A | K | T | E | E | E |
| Query Conservation |   |
  |   |   |
|   |
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|   |   |   |   |
|   |
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| Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
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| Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
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E | K | Q | V | M | M | F | S | A | T | L | S | K | E | I | R | P |
| Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | S | S |  |  |  |  |  |  | S | S |
|
| T | T |  |  |  |
| Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
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| Template SS confidence |   |
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221 | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . |
|   |
|   |   |
386 | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . |
| Predicted Secondary structure |   |
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| Query SS confidence |   |
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| Query Sequence |   |
E | F | R | N | I | Y | N | M | T | V | T | Q | I | P | T | N | K | P | V | Q | R | N | D | K | S | D | L | I | Y | I | S | Q | K | G | K | F | D | A | V | V | E | D | V | V | E | K | H | K | A | G | Q | P | V | L | L | G | T | V | A | V | E | T | S | E | Y | I | S | N | L | L | K | K | R | G | I | R | H | D | V | L |
| Query Conservation |   |
|   |   |   |
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| Alig confidence |   |
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| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
V | C | R | K | F | M | Q | D | P | M | E | I | F | V | D | D | E | T | K | L | T | L | H | G | L | Q | Q | Y | Y | V | K | L | K | D | N | E | K | N | R | K | L | F | D | L | L | D | V | L | E | F | N | Q | V | V | I | F | V | K | S | V | Q | R | C | I | A | L | A | Q | L | L | V | E | Q | N | F | P | A | I | A | I |
| Template Known Secondary structure |   |
 |  |  |  |  |
| S | S |
|  |  |  |  |
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| T | T |
|  |  |  |  |  |  |
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|  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
| S |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
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|  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |
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| Template SS confidence |   |
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|   |   |
238 | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . |
|   |
|   |   |
466 | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | |
|
. | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | |
. | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . |
| Predicted Secondary structure |   |
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| . | . |
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| Query SS confidence |   |
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| Query Sequence |   |
N | A | K | N | H | E | R | E | A | E | I | V | A | G | A | G | Q | K | G | . |
. |
A | V | T | I | A | T | N | M | A | G | R | G | T | D | I | K | L | G | E | G | V | E | E | L | G | G | L | . |
A | V | I | G | T | E | R | H | E | S | R | R | I | D | D | Q | L | R | G | R | S | G | R | Q | G | D | K | G | D | S | R |
| Query Conservation |   |
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| Alig confidence |   |
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| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
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|   |   |   |   |   |
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| . | . | . | . | . | . | . | . | . |   |
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| Template Sequence |   |
H | R | G | M | P | Q | E | E | R | L | S | R | Y | Q | Q | F | K | D | F | Q | R | R | I | L | V | A | T | N | L | F | G | R | G | M | D | I | E | . |
. |
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R | V | N | I | A | F | N | Y | D | M | P | E | D | S | D | T | Y | L | H | R | V | A | R | A | G | R | F | G | T | K | G | L | A | I |
| Template Known Secondary structure |   |
| S | S | S |
|  |  |  |  |  |  |  |  |  |  | T | T |
|
| S | S |
|  |  |  |  | S |
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| T | T |
| B |
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| T | . | . | . | . | . | . | . | . | . | T |  |  |  |  |  |  | S | S |
|
| S | S | T | T |  |  |  |  |  | S |
| B |
| S | S | S |
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| Template Predicted Secondary structure |   |
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|  |  |  |  |  |  |  |  |  |  |
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| Template SS confidence |   |
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|   |   |
318 | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | |
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. | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . |
|   |
|   |   |
543 | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |
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|  |  |  |  |  |  |
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|  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
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| Query Sequence |   |
F | Y | L | S | L | Q | D | E | L | M | I | R | F | G | S | E | R | L | Q | K | M | M | S | R | L | G | L | D | D | S | T | P | I | E | S | K | M | V | S | R | A | V | E | S |
| Query Conservation |   |
|   |
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|   |
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|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |
| Alig confidence |   |
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| . | . | . | . | . | . |
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| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |
|   |
| Template Sequence |   |
T | F | V | S | D | E | N | D | A | K | I | . |
. |
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L | N | D | V | Q | D | R | F | E | V | N | I | S | E | L | P | D | E | I | D | I | S | S | Y | I | E | Q |
| Template Known Secondary structure |   |
 |  |  |
| S | T | T |  |  |  |  | . | . | . | . | . | . |  |  |  |  |  |  |  | T | T |
|
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|  |  |
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| S |
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|  |  |  |  | S | T | T |
| Template Predicted Secondary structure |   |
 |  |  |
|  |  |  |  |  |  |  | . | . | . | . | . | . |  |  |  |  |  |  |  |  |
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|  |  |  |  |  |  |  |  |  |
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| Template SS confidence |   |
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|   |   |
389 | 390 | . | . | . | . | . | . | . | . | . | |
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400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . |
|   |